Meta-analysis of Chemical exposure and increased risk of hematologic malignancies.
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.34624/jshd.v4i2.24961 |
Resumo: | Background: Exposure to environmental risk factors may be associated with the development of hematologic malignancies, as pointed by evidence in the literature. Despite this, most studies refer to a specific risk factor or disease. Objective: To assess this issue globally, in this study we performed a meta-analysis. Methods: A searched PubMed database was done in 2020 and a selection of 35 case-control and cohort studies published between 1990 and 2020 was done. Results: Was observed a significant adverse association between exposure to organic solvents such as benzene and incidence of myeloid malignancies. For agricultural chemicals (pesticides, herbicides, insecticides), an adverse association was found for both lymphoid and myeloid malignancies. Conclusions: The results suggest that activities in chemical industries or agriculture pose greater risk and should be closely monitored. Prospective occupational surveys are needed to identify exposure–response relationships and clarify disease mechanisms. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Meta-analysis of Chemical exposure and increased risk of hematologic malignancies.Background: Exposure to environmental risk factors may be associated with the development of hematologic malignancies, as pointed by evidence in the literature. Despite this, most studies refer to a specific risk factor or disease. Objective: To assess this issue globally, in this study we performed a meta-analysis. Methods: A searched PubMed database was done in 2020 and a selection of 35 case-control and cohort studies published between 1990 and 2020 was done. Results: Was observed a significant adverse association between exposure to organic solvents such as benzene and incidence of myeloid malignancies. For agricultural chemicals (pesticides, herbicides, insecticides), an adverse association was found for both lymphoid and myeloid malignancies. Conclusions: The results suggest that activities in chemical industries or agriculture pose greater risk and should be closely monitored. Prospective occupational surveys are needed to identify exposure–response relationships and clarify disease mechanisms.University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV)2022-12-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34624/jshd.v4i2.24961https://doi.org/10.34624/jshd.v4i2.24961Journal of Statistics on Health Decision; Vol 4 No 2 (2022); e24961Journal of Statistics on Health Decision; vol. 4 n.º 2 (2022); e249612184-5794reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://proa.ua.pt/index.php/jshd/article/view/24961https://proa.ua.pt/index.php/jshd/article/view/24961/21315Copyright (c) 2022 Gisela Ferreira, Vera Afreixo, Adela Iutis, Raquel Silvahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessFerreira, GiselaAfreixo, VeraIutis, AdelaSilva, Raquel2023-01-05T22:30:14Zoai:proa.ua.pt:article/24961Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:29:30.808891Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
title |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
spellingShingle |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. Ferreira, Gisela |
title_short |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
title_full |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
title_fullStr |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
title_full_unstemmed |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
title_sort |
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies. |
author |
Ferreira, Gisela |
author_facet |
Ferreira, Gisela Afreixo, Vera Iutis, Adela Silva, Raquel |
author_role |
author |
author2 |
Afreixo, Vera Iutis, Adela Silva, Raquel |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Ferreira, Gisela Afreixo, Vera Iutis, Adela Silva, Raquel |
description |
Background: Exposure to environmental risk factors may be associated with the development of hematologic malignancies, as pointed by evidence in the literature. Despite this, most studies refer to a specific risk factor or disease. Objective: To assess this issue globally, in this study we performed a meta-analysis. Methods: A searched PubMed database was done in 2020 and a selection of 35 case-control and cohort studies published between 1990 and 2020 was done. Results: Was observed a significant adverse association between exposure to organic solvents such as benzene and incidence of myeloid malignancies. For agricultural chemicals (pesticides, herbicides, insecticides), an adverse association was found for both lymphoid and myeloid malignancies. Conclusions: The results suggest that activities in chemical industries or agriculture pose greater risk and should be closely monitored. Prospective occupational surveys are needed to identify exposure–response relationships and clarify disease mechanisms. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.34624/jshd.v4i2.24961 https://doi.org/10.34624/jshd.v4i2.24961 |
url |
https://doi.org/10.34624/jshd.v4i2.24961 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://proa.ua.pt/index.php/jshd/article/view/24961 https://proa.ua.pt/index.php/jshd/article/view/24961/21315 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Gisela Ferreira, Vera Afreixo, Adela Iutis, Raquel Silva http://creativecommons.org/licenses/by-nc-nd/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Gisela Ferreira, Vera Afreixo, Adela Iutis, Raquel Silva http://creativecommons.org/licenses/by-nc-nd/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV) |
publisher.none.fl_str_mv |
University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV) |
dc.source.none.fl_str_mv |
Journal of Statistics on Health Decision; Vol 4 No 2 (2022); e24961 Journal of Statistics on Health Decision; vol. 4 n.º 2 (2022); e24961 2184-5794 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130752385810432 |