Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study

Detalhes bibliográficos
Autor(a) principal: Cardoso-Martins, Inês
Data de Publicação: 2022
Outros Autores: Pessanha, Sofia, Coelho, Ana, Arantes-Oliveira, Sofia, Marques, Paula F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/150494
Resumo: Funding Information: This research was funded by Fundação para a Ciência e Tecnologia (FCT) (Portugal) by the research center grant UID/FIS/04559/2021 to LIBPhys from the FCT/MCTES/PIDDAC, Portugal. Publisher Copyright: © 2022 by the authors.
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spelling Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Studydental enamelelectron scanning microscopyenamelmolar–incisor hypomineralizationpediatric dentistryRaman spectroscopytooth remineralizationMedicine (miscellaneous)Biochemistry, Genetics and Molecular Biology(all)Funding Information: This research was funded by Fundação para a Ciência e Tecnologia (FCT) (Portugal) by the research center grant UID/FIS/04559/2021 to LIBPhys from the FCT/MCTES/PIDDAC, Portugal. Publisher Copyright: © 2022 by the authors.Remineralization of tooth enamel can be achieved by applying a complex of casein phosphopeptides and amorphous calcium phosphate (CPP-ACP). However, the efficacy and optimization of this agent in molar–incisor hypomineralization (MIH) lacks evidence. The purpose of this study is to evaluate the efficacy of CPP-ACP tooth mousse in remineralizing MIH-affected enamel in an optimized 28-day protocol using polarized Raman microscopy and scanning electron microscopy. The protocol was applied to two types of MIH opacities, white and yellow, and compared against sound enamel specimens before and after treatment. Data was analyzed using a one-way ANOVA and LSD post hoc multiple comparisons test (p < 0.05) for the Raman analysis. Hypomineralized enamel showed an improvement of its structure after CPP-ACP supplementation. In addition, Raman spectroscopy results showed a decrease in the depolarization ratio of the symmetric stretching band of phosphate (p < 0.05 for both groups). In conclusion, there was an improvement in mineral density and organization of the hypomineralized enamel after treatment with CPP-ACP tooth mousse.DF – Departamento de FísicaRUNCardoso-Martins, InêsPessanha, SofiaCoelho, AnaArantes-Oliveira, SofiaMarques, Paula F.2023-03-13T22:27:48Z2022-12-012022-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11application/pdfhttp://hdl.handle.net/10362/150494eng2227-9059PURE: 55561731https://doi.org/10.3390/biomedicines10123086info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:32:29Zoai:run.unl.pt:10362/150494Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:09.087115Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
title Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
spellingShingle Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
Cardoso-Martins, Inês
dental enamel
electron scanning microscopy
enamel
molar–incisor hypomineralization
pediatric dentistry
Raman spectroscopy
tooth remineralization
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
title_short Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
title_full Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
title_fullStr Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
title_full_unstemmed Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
title_sort Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in Molar-Incisor Hypomineralized Teeth Using Polarized Raman and Scanning Electron Microscopy—An In Vitro Study
author Cardoso-Martins, Inês
author_facet Cardoso-Martins, Inês
Pessanha, Sofia
Coelho, Ana
Arantes-Oliveira, Sofia
Marques, Paula F.
author_role author
author2 Pessanha, Sofia
Coelho, Ana
Arantes-Oliveira, Sofia
Marques, Paula F.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv DF – Departamento de Física
RUN
dc.contributor.author.fl_str_mv Cardoso-Martins, Inês
Pessanha, Sofia
Coelho, Ana
Arantes-Oliveira, Sofia
Marques, Paula F.
dc.subject.por.fl_str_mv dental enamel
electron scanning microscopy
enamel
molar–incisor hypomineralization
pediatric dentistry
Raman spectroscopy
tooth remineralization
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
topic dental enamel
electron scanning microscopy
enamel
molar–incisor hypomineralization
pediatric dentistry
Raman spectroscopy
tooth remineralization
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
description Funding Information: This research was funded by Fundação para a Ciência e Tecnologia (FCT) (Portugal) by the research center grant UID/FIS/04559/2021 to LIBPhys from the FCT/MCTES/PIDDAC, Portugal. Publisher Copyright: © 2022 by the authors.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-01
2022-12-01T00:00:00Z
2023-03-13T22:27:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/150494
url http://hdl.handle.net/10362/150494
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2227-9059
PURE: 55561731
https://doi.org/10.3390/biomedicines10123086
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 11
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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