Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency.

• Autor(a) principal: Fernández-Elías, V.E
• Data de Publicação: 2022
• Outros Autores: Tornero-Aguilera, J.F., Parraca, J.A., Clemente-Suárez, V.J.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10174/34239; https://doi.org/Fernández-Elías, V.E.; Tornero-Aguilera, J.F.; Parraca, J.A.; Clemente-Suárez, V.J. (2022). Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency. Int. J. Environ. Res. Public Health 2022, 19, 11516. https://doi.org/10.3390/ijerph191811516; https://doi.org/10.3390/ijerph191811516
• topic: psychological stress; hyperammonemia; case report; Ornithine Transcarbamylase deficiency (OTCD); metabolic stress response

An 18-year-old male motorcycle racer, who was a participant in the FIM Road RacingWorld Championship and had a history of Ornithine Transcarbamylase deficiency, developed nausea and dizziness while driving his motorcycle and became unconscious right after he stopped at the box. He was rapidly attended to by the medical personnel of the circuit, and once he recovered consciousness, he was taken to the local hospital where the blood analysis showed hyperammonemia (307 _g/dL) and excess alkalosis. The patient was properly following the prescribed treatment, and there were no environmental stressors. Hence, psychological stress and its somatization due to the risky task that the patient was performing could have triggered the episode. Stress must be considered as a potential cause, triggering strenuous metabolic stress that leads to hyperammonemia.