Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools

Detalhes bibliográficos
Autor(a) principal: Elamine, Youssef
Data de Publicação: 2021
Outros Autores: Imtara, Hamada, Miguel, Maria Graça, Anjos, Ofélia, Estevinho, Letícia M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/21475
Resumo: The emergence of multidrug-resistant bacteria has prompted the development of alternative therapies, including the use of natural products with antibacterial properties. The antibacterial properties of Zantaz honey produced in the Moroccan Atlas Mountains against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was evaluated and analyzed using chemometric tools. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) against S. aureus were the lowest (112.5 54.5 mg/mL), revealing that this species was most sensitive to Zantaz honey. P. aeruginosa showed an intermediate sensitivity (MIC= 118.75 51.9 mg/mL), while E. coli was the most resistant to treatment (MIC = 175 61.2 mg/mL). Content of monosaccharides, certain minerals, and phenolic compounds correlated with antibacterial activity (p < 0.05). Principal component analysis of physicochemical characteristics and antibacterial activity indicated that the parameters most associated with antibacterial activity were color, acidity, and content of melanoidins, fructose, epicatechin, methyl syringate, 4-coumaric acid, and 3-coumaric acid
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spelling Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric toolsBupleurum spinosummethyl syringateEscherichia coliPseudomonas aeruginosaStaphylococcus aureusThe emergence of multidrug-resistant bacteria has prompted the development of alternative therapies, including the use of natural products with antibacterial properties. The antibacterial properties of Zantaz honey produced in the Moroccan Atlas Mountains against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was evaluated and analyzed using chemometric tools. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) against S. aureus were the lowest (112.5 54.5 mg/mL), revealing that this species was most sensitive to Zantaz honey. P. aeruginosa showed an intermediate sensitivity (MIC= 118.75 51.9 mg/mL), while E. coli was the most resistant to treatment (MIC = 175 61.2 mg/mL). Content of monosaccharides, certain minerals, and phenolic compounds correlated with antibacterial activity (p < 0.05). Principal component analysis of physicochemical characteristics and antibacterial activity indicated that the parameters most associated with antibacterial activity were color, acidity, and content of melanoidins, fructose, epicatechin, methyl syringate, 4-coumaric acid, and 3-coumaric acidMDPIRepositório da Universidade de LisboaElamine, YoussefImtara, HamadaMiguel, Maria GraçaAnjos, OféliaEstevinho, Letícia M.2021-06-17T13:11:34Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/21475engElamine, Y.; Imtara, H.; Miguel, M.G.; Anjos, O.; Estevinho, L.M.; Alaiz, M.; Girón-Calle, J.; Vioque, J.; Martín, J.; Lyoussi, B. Antibacterial Activity of Moroccan Zantaz Honey and the Influence of Its Physicochemical Parameters Using Chemometric Tools. Appl. Sci. 2021, 11, 4675https://doi.org/10.3390/ app11104675info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:50:55Zoai:www.repository.utl.pt:10400.5/21475Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:06:03.388370Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
title Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
spellingShingle Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
Elamine, Youssef
Bupleurum spinosum
methyl syringate
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
title_short Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
title_full Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
title_fullStr Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
title_full_unstemmed Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
title_sort Antibacterial activity of Maroccan Zantaz honey and the influence of its physicochemical parameters using chemometric tools
author Elamine, Youssef
author_facet Elamine, Youssef
Imtara, Hamada
Miguel, Maria Graça
Anjos, Ofélia
Estevinho, Letícia M.
author_role author
author2 Imtara, Hamada
Miguel, Maria Graça
Anjos, Ofélia
Estevinho, Letícia M.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Elamine, Youssef
Imtara, Hamada
Miguel, Maria Graça
Anjos, Ofélia
Estevinho, Letícia M.
dc.subject.por.fl_str_mv Bupleurum spinosum
methyl syringate
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
topic Bupleurum spinosum
methyl syringate
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
description The emergence of multidrug-resistant bacteria has prompted the development of alternative therapies, including the use of natural products with antibacterial properties. The antibacterial properties of Zantaz honey produced in the Moroccan Atlas Mountains against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was evaluated and analyzed using chemometric tools. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) against S. aureus were the lowest (112.5 54.5 mg/mL), revealing that this species was most sensitive to Zantaz honey. P. aeruginosa showed an intermediate sensitivity (MIC= 118.75 51.9 mg/mL), while E. coli was the most resistant to treatment (MIC = 175 61.2 mg/mL). Content of monosaccharides, certain minerals, and phenolic compounds correlated with antibacterial activity (p < 0.05). Principal component analysis of physicochemical characteristics and antibacterial activity indicated that the parameters most associated with antibacterial activity were color, acidity, and content of melanoidins, fructose, epicatechin, methyl syringate, 4-coumaric acid, and 3-coumaric acid
publishDate 2021
dc.date.none.fl_str_mv 2021-06-17T13:11:34Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/21475
url http://hdl.handle.net/10400.5/21475
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Elamine, Y.; Imtara, H.; Miguel, M.G.; Anjos, O.; Estevinho, L.M.; Alaiz, M.; Girón-Calle, J.; Vioque, J.; Martín, J.; Lyoussi, B. Antibacterial Activity of Moroccan Zantaz Honey and the Influence of Its Physicochemical Parameters Using Chemometric Tools. Appl. Sci. 2021, 11, 4675
https://doi.org/10.3390/ app11104675
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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