Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/24023 |
Resumo: | Honey is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl- 1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications. |
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Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extractsHoneyPhenolic compoundsAntioxidant activityEuphorbia resiniferaEuphorbia officinarumPhenolic profileHoney is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl- 1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications.This research was funded by the Fundação para a Ciência e a Tecnologia I.P. (FCT), Portugal: UIDB/05183/2020, UIDB/04326/2020, UIDB/00690/2020, UID/MAR/00350/2020, UIDB/04449/2020, UIDP/04449/2020, CEECIND/00791/2017.Biblioteca Digital do IPBBoutoub, OumaimaEl-Guendouz, SoukaïnaManhita, AnaDias, Cristina BarrocasEstevinho, Leticia M.Paula, Vanessa B.Carlier, Jorge D.Costa, Maria ClaraRodrigues, BrígidaRaposo, SaraAazza, SmailEl Ghadraoui, LahsenMiguel, Maria da Graça2021-10-14T15:58:41Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/24023engBoutoub, Oumaima; El-Guendouz, Soukaina; Manhita, Ana; Dias, Cristina Barrocas; Estevinho, Letícia M.; Paula, Vanessa B.; Carlier, Jorge; Costa, Maria Clara; Rodrigues, Brígida; Raposo, Sara; Aazza, Smail; El Ghadraoui, Lahsen; Miguel, Maria Graça (2021). Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts. Foods. ISSN 2304-8158. 10:8, p. 1-212304-815810.3390/foods10081909info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:53:41Zoai:bibliotecadigital.ipb.pt:10198/24023Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:14:54.622928Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
title |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
spellingShingle |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts Boutoub, Oumaima Honey Phenolic compounds Antioxidant activity Euphorbia resinifera Euphorbia officinarum Phenolic profile |
title_short |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
title_full |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
title_fullStr |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
title_full_unstemmed |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
title_sort |
Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts |
author |
Boutoub, Oumaima |
author_facet |
Boutoub, Oumaima El-Guendouz, Soukaïna Manhita, Ana Dias, Cristina Barrocas Estevinho, Leticia M. Paula, Vanessa B. Carlier, Jorge D. Costa, Maria Clara Rodrigues, Brígida Raposo, Sara Aazza, Smail El Ghadraoui, Lahsen Miguel, Maria da Graça |
author_role |
author |
author2 |
El-Guendouz, Soukaïna Manhita, Ana Dias, Cristina Barrocas Estevinho, Leticia M. Paula, Vanessa B. Carlier, Jorge D. Costa, Maria Clara Rodrigues, Brígida Raposo, Sara Aazza, Smail El Ghadraoui, Lahsen Miguel, Maria da Graça |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Boutoub, Oumaima El-Guendouz, Soukaïna Manhita, Ana Dias, Cristina Barrocas Estevinho, Leticia M. Paula, Vanessa B. Carlier, Jorge D. Costa, Maria Clara Rodrigues, Brígida Raposo, Sara Aazza, Smail El Ghadraoui, Lahsen Miguel, Maria da Graça |
dc.subject.por.fl_str_mv |
Honey Phenolic compounds Antioxidant activity Euphorbia resinifera Euphorbia officinarum Phenolic profile |
topic |
Honey Phenolic compounds Antioxidant activity Euphorbia resinifera Euphorbia officinarum Phenolic profile |
description |
Honey is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl- 1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-14T15:58:41Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/24023 |
url |
http://hdl.handle.net/10198/24023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Boutoub, Oumaima; El-Guendouz, Soukaina; Manhita, Ana; Dias, Cristina Barrocas; Estevinho, Letícia M.; Paula, Vanessa B.; Carlier, Jorge; Costa, Maria Clara; Rodrigues, Brígida; Raposo, Sara; Aazza, Smail; El Ghadraoui, Lahsen; Miguel, Maria Graça (2021). Comparative study of the antioxidant and enzyme inhibitory activities of two types of moroccan euphorbia entire honey and their phenolic extracts. Foods. ISSN 2304-8158. 10:8, p. 1-21 2304-8158 10.3390/foods10081909 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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