Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/16929 |
Resumo: | There are global concerns about dietary exposure to metal(loid)s in foods. However, little is known about the relative contribution of rice versus fish to multiple metal(loid) exposure for the general population, especially in Asia where rice and fish are major food sources. We compared relative contributions of rice and fish consumption to multi-metal(loid) exposure on the city-scale (Nanjing) and province-scale in China. The effects of ingestion rate, metal(loid) level, and bioaccessibility were examined to calculate modeled risk from Cu, Zn, total As (TAs), inorganic As (iAs), Se, Cd, Pb, and methylmercury (MeHg). Metal(loid) levels in rice and fish samples collected from Nanjing City were generally low, except iAs. Metal(loid) bioaccessibilities in fish were higher than those in rice, except Se. Calculated carcinogenic risks induced by iAs intake (indicated by increased lifetime cancer risk, ILCR) were above the acceptable level (1 0 − 4) in Nanjing City (median: 3 × 10− 4 for female and 4 × 10− 4 for male) and nine provinces (1.4 × 10− 4 to 5.9 × 10− 4) in China. Rice consumption accounted for 85.0% to 99.8% of carcinogenic risk. The non-carcinogenic hazard quotients (HQ) for single metals and hazard index (HI) for multi-metal exposure were < 1 in all cases, indicating of their slight non-carcinogen health effects associated. In Guangdong and Jiangsu provinces, results showed that rice and fish intake contributed similarly to the HI (i.e., 42.6% vs 57.4% in Guangdong and 54.6% vs 45.4% in Jiangsu). Sensitivity analysis indicated that carcinogenic risk was most sensitive to rice ingestion rate and rice iAs levels, while non-carcinogenic hazard (i.e., HQ and HI) was most sensitive to ingestion rate of fish and rice, and Cu concentration in rice. Our results suggest that rice is more important than fish for human dietary metal(loid) exposure risk in China, and carcinogenic risk from iAs exposure in rice requires particular attention. |
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Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern ChinaMetalBioavailabilityFishRiceRisk AssessmentDietary ExposureThere are global concerns about dietary exposure to metal(loid)s in foods. However, little is known about the relative contribution of rice versus fish to multiple metal(loid) exposure for the general population, especially in Asia where rice and fish are major food sources. We compared relative contributions of rice and fish consumption to multi-metal(loid) exposure on the city-scale (Nanjing) and province-scale in China. The effects of ingestion rate, metal(loid) level, and bioaccessibility were examined to calculate modeled risk from Cu, Zn, total As (TAs), inorganic As (iAs), Se, Cd, Pb, and methylmercury (MeHg). Metal(loid) levels in rice and fish samples collected from Nanjing City were generally low, except iAs. Metal(loid) bioaccessibilities in fish were higher than those in rice, except Se. Calculated carcinogenic risks induced by iAs intake (indicated by increased lifetime cancer risk, ILCR) were above the acceptable level (1 0 − 4) in Nanjing City (median: 3 × 10− 4 for female and 4 × 10− 4 for male) and nine provinces (1.4 × 10− 4 to 5.9 × 10− 4) in China. Rice consumption accounted for 85.0% to 99.8% of carcinogenic risk. The non-carcinogenic hazard quotients (HQ) for single metals and hazard index (HI) for multi-metal exposure were < 1 in all cases, indicating of their slight non-carcinogen health effects associated. In Guangdong and Jiangsu provinces, results showed that rice and fish intake contributed similarly to the HI (i.e., 42.6% vs 57.4% in Guangdong and 54.6% vs 45.4% in Jiangsu). Sensitivity analysis indicated that carcinogenic risk was most sensitive to rice ingestion rate and rice iAs levels, while non-carcinogenic hazard (i.e., HQ and HI) was most sensitive to ingestion rate of fish and rice, and Cu concentration in rice. Our results suggest that rice is more important than fish for human dietary metal(loid) exposure risk in China, and carcinogenic risk from iAs exposure in rice requires particular attention.2020YFC1807502, 21637002, U2032201, 41822709, BK20200322, CSC201806190209ElsevierSapientiaWang, WenqinGong, YuGreenfield, Ben K.Nunes, LuísYang, QianqiLei, PeiBu, WenboWang, BinZhao, XiaomiaoHuang, LeiZhong, Huan2021-09-02T15:57:26Z2021-102021-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/16929eng10.1016/j.envint.2021.1066821873-6750info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:28:57Zoai:sapientia.ualg.pt:10400.1/16929Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:06:57.937458Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
title |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
spellingShingle |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China Wang, Wenqin Metal Bioavailability Fish Rice Risk Assessment Dietary Exposure |
title_short |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
title_full |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
title_fullStr |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
title_full_unstemmed |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
title_sort |
Relative contribution of rice and fish consumption to bioaccessibility-corrected health risks for urban residents in eastern China |
author |
Wang, Wenqin |
author_facet |
Wang, Wenqin Gong, Yu Greenfield, Ben K. Nunes, Luís Yang, Qianqi Lei, Pei Bu, Wenbo Wang, Bin Zhao, Xiaomiao Huang, Lei Zhong, Huan |
author_role |
author |
author2 |
Gong, Yu Greenfield, Ben K. Nunes, Luís Yang, Qianqi Lei, Pei Bu, Wenbo Wang, Bin Zhao, Xiaomiao Huang, Lei Zhong, Huan |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Wang, Wenqin Gong, Yu Greenfield, Ben K. Nunes, Luís Yang, Qianqi Lei, Pei Bu, Wenbo Wang, Bin Zhao, Xiaomiao Huang, Lei Zhong, Huan |
dc.subject.por.fl_str_mv |
Metal Bioavailability Fish Rice Risk Assessment Dietary Exposure |
topic |
Metal Bioavailability Fish Rice Risk Assessment Dietary Exposure |
description |
There are global concerns about dietary exposure to metal(loid)s in foods. However, little is known about the relative contribution of rice versus fish to multiple metal(loid) exposure for the general population, especially in Asia where rice and fish are major food sources. We compared relative contributions of rice and fish consumption to multi-metal(loid) exposure on the city-scale (Nanjing) and province-scale in China. The effects of ingestion rate, metal(loid) level, and bioaccessibility were examined to calculate modeled risk from Cu, Zn, total As (TAs), inorganic As (iAs), Se, Cd, Pb, and methylmercury (MeHg). Metal(loid) levels in rice and fish samples collected from Nanjing City were generally low, except iAs. Metal(loid) bioaccessibilities in fish were higher than those in rice, except Se. Calculated carcinogenic risks induced by iAs intake (indicated by increased lifetime cancer risk, ILCR) were above the acceptable level (1 0 − 4) in Nanjing City (median: 3 × 10− 4 for female and 4 × 10− 4 for male) and nine provinces (1.4 × 10− 4 to 5.9 × 10− 4) in China. Rice consumption accounted for 85.0% to 99.8% of carcinogenic risk. The non-carcinogenic hazard quotients (HQ) for single metals and hazard index (HI) for multi-metal exposure were < 1 in all cases, indicating of their slight non-carcinogen health effects associated. In Guangdong and Jiangsu provinces, results showed that rice and fish intake contributed similarly to the HI (i.e., 42.6% vs 57.4% in Guangdong and 54.6% vs 45.4% in Jiangsu). Sensitivity analysis indicated that carcinogenic risk was most sensitive to rice ingestion rate and rice iAs levels, while non-carcinogenic hazard (i.e., HQ and HI) was most sensitive to ingestion rate of fish and rice, and Cu concentration in rice. Our results suggest that rice is more important than fish for human dietary metal(loid) exposure risk in China, and carcinogenic risk from iAs exposure in rice requires particular attention. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-02T15:57:26Z 2021-10 2021-10-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/16929 |
url |
http://hdl.handle.net/10400.1/16929 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.envint.2021.106682 1873-6750 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
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