Drug-induced photosensitivity

Detalhes bibliográficos
Autor(a) principal: Pereira,Ana Sofia
Data de Publicação: 2022
Outros Autores: Xará,Joana, Gonçalo,Margarida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104
Resumo: Abstract Drug photosensitivity is a relatively frequent adverse event, although not always recognized due to its clinical polymorphism and difficulties in performing tests to prove drug causality. The aim of this report is to review the mechanisms of photosensitivity related with topical and systemic drugs (phototoxicity, photoallergy, autoimmunity, and enhanced photocarcinogenesis), the main acute and delayed clinical manifestations (acute sunburn or eczema, pseudoporphyria, photo-onycholysis, dyschromia, telangiectasia, subacute lupus erythematosus, pre-cancerous lesions, and cutaneous neoplasia), the main culprits [non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobials, like fluoroquinolones and tetracyclines, psychotropic, anticancer, and cardiovascular drugs] and the most adequate diagnostic procedures (photopatch and drug photoprovocation tests).
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spelling Drug-induced photosensitivityAdverse drug eventPhotosensitivityPhotoallergyPhototoxicityPhotocarcinogenesisAbstract Drug photosensitivity is a relatively frequent adverse event, although not always recognized due to its clinical polymorphism and difficulties in performing tests to prove drug causality. The aim of this report is to review the mechanisms of photosensitivity related with topical and systemic drugs (phototoxicity, photoallergy, autoimmunity, and enhanced photocarcinogenesis), the main acute and delayed clinical manifestations (acute sunburn or eczema, pseudoporphyria, photo-onycholysis, dyschromia, telangiectasia, subacute lupus erythematosus, pre-cancerous lesions, and cutaneous neoplasia), the main culprits [non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobials, like fluoroquinolones and tetracyclines, psychotropic, anticancer, and cardiovascular drugs] and the most adequate diagnostic procedures (photopatch and drug photoprovocation tests).Permanyer Publications2022-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104Portuguese Journal of Dermatology and Venereology v.80 n.2 2022reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104Pereira,Ana SofiaXará,JoanaGonçalo,Margaridainfo:eu-repo/semantics/openAccess2024-02-08T23:00:30Zoai:scielo:S2795-50012022000200104Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:36:53.998488Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Drug-induced photosensitivity
title Drug-induced photosensitivity
spellingShingle Drug-induced photosensitivity
Pereira,Ana Sofia
Adverse drug event
Photosensitivity
Photoallergy
Phototoxicity
Photocarcinogenesis
title_short Drug-induced photosensitivity
title_full Drug-induced photosensitivity
title_fullStr Drug-induced photosensitivity
title_full_unstemmed Drug-induced photosensitivity
title_sort Drug-induced photosensitivity
author Pereira,Ana Sofia
author_facet Pereira,Ana Sofia
Xará,Joana
Gonçalo,Margarida
author_role author
author2 Xará,Joana
Gonçalo,Margarida
author2_role author
author
dc.contributor.author.fl_str_mv Pereira,Ana Sofia
Xará,Joana
Gonçalo,Margarida
dc.subject.por.fl_str_mv Adverse drug event
Photosensitivity
Photoallergy
Phototoxicity
Photocarcinogenesis
topic Adverse drug event
Photosensitivity
Photoallergy
Phototoxicity
Photocarcinogenesis
description Abstract Drug photosensitivity is a relatively frequent adverse event, although not always recognized due to its clinical polymorphism and difficulties in performing tests to prove drug causality. The aim of this report is to review the mechanisms of photosensitivity related with topical and systemic drugs (phototoxicity, photoallergy, autoimmunity, and enhanced photocarcinogenesis), the main acute and delayed clinical manifestations (acute sunburn or eczema, pseudoporphyria, photo-onycholysis, dyschromia, telangiectasia, subacute lupus erythematosus, pre-cancerous lesions, and cutaneous neoplasia), the main culprits [non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobials, like fluoroquinolones and tetracyclines, psychotropic, anticancer, and cardiovascular drugs] and the most adequate diagnostic procedures (photopatch and drug photoprovocation tests).
publishDate 2022
dc.date.none.fl_str_mv 2022-06-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200104
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Permanyer Publications
publisher.none.fl_str_mv Permanyer Publications
dc.source.none.fl_str_mv Portuguese Journal of Dermatology and Venereology v.80 n.2 2022
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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