Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal

Detalhes bibliográficos
Autor(a) principal: Morgado, Manuel
Data de Publicação: 2010
Outros Autores: Rolo, Sandra, Pereira, Luísa, Sousa, Miguel Castelo-Branco Craveiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/657
Resumo: http://www.ncbi.nlm.nih.gov/pubmed/21192829
id RCAP_ea1ad94b3f4342a35e8c4c6503f0025f
oai_identifier_str oai:ubibliorum.ubi.pt:10400.6/657
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of PortugalHypertensionBlood pressureAntihypertensivesTreatmentControlPortugalhttp://www.ncbi.nlm.nih.gov/pubmed/21192829BACKGROUND: Interventions to improve blood pressure control in hypertension have had limited success in clinical practice despite evidence of cardiovascular disease prevention in randomised controlled trials. The objectives of this study were to evaluate blood pressure control and antihypertensive pharmacotherapy patterns in a population of Eastern Central Region of Portugal, attending a hospital outpatient clinic (ambulatory setting) for routine follow-up. METHODS: Medical data of all patients that attended at least two medical appointments of hypertension / dyslipidemia in a university hospital over a one and a half year period (from January 2008 to June 2009) were retrospectively analysed. Demographic variables, clinical data and blood pressure values of hypertensive patients included in the study, as well as prescribing metrics were examined on a descriptive basis and expressed as the mean +/- SD, frequency and percentages. Student's test and Mann-Whitney rank sum test were used to compare continuous variables and chi-square test and Fisher exact probability test were used to test for differences between categorical variables. RESULTS: In all, 37% of hypertensive patients (n=76) had their blood pressure controlled according to international guidelines. About 45.5% of patients with a target blood pressure <140/90 mmHg (n=156) were controlled, whereas in patients with diabetes or chronic kidney disease (n=49) the corresponding figure was only 10.2% (P<0.001). Among patients initiating hypertension / dyslipidemia consultation within the study period 32.1% had stage 2 hypertension in the first appointment, but this figure decreased to 3.6% in the last consultation (P=0.012). Thiazide-type diuretics were the most prescribed antihypertensive drugs (67%) followed by angiotensin receptor blockers (60%) and beta-blockers (43%). About 95.9% patients with comorbid diabetes were treated with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. CONCLUSIONS: Clinically important blood pressure decreases can be achieved soon after hypertension medical appointment initiation. However, many hypertensive patients prescribed with antihypertensive therapy fail to achieve blood pressure control in clinical practice, this control being worse among patients with diabetes or chronic kidney disease. As pharmacotherapy patterns seem to coincide with international guidelines, further research is needed to identify the causes of poor blood pressure control.This work was supported by Fundação para a Ciência e a Tecnologia (SFRH/BD/36756/2007) through a fellowship grant attributed to Manuel Morgado.Jigisha Patel MRCP, PhDuBibliorumMorgado, ManuelRolo, SandraPereira, LuísaSousa, Miguel Castelo-Branco Craveiro2011-01-08T01:23:32Z2010-122010-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/657eng1472-6963DOI: 10.1186/1472-6963-10-349info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:35:58Zoai:ubibliorum.ubi.pt:10400.6/657Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:42.350104Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
title Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
spellingShingle Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
Morgado, Manuel
Hypertension
Blood pressure
Antihypertensives
Treatment
Control
Portugal
title_short Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
title_full Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
title_fullStr Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
title_full_unstemmed Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
title_sort Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
author Morgado, Manuel
author_facet Morgado, Manuel
Rolo, Sandra
Pereira, Luísa
Sousa, Miguel Castelo-Branco Craveiro
author_role author
author2 Rolo, Sandra
Pereira, Luísa
Sousa, Miguel Castelo-Branco Craveiro
author2_role author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Morgado, Manuel
Rolo, Sandra
Pereira, Luísa
Sousa, Miguel Castelo-Branco Craveiro
dc.subject.por.fl_str_mv Hypertension
Blood pressure
Antihypertensives
Treatment
Control
Portugal
topic Hypertension
Blood pressure
Antihypertensives
Treatment
Control
Portugal
description http://www.ncbi.nlm.nih.gov/pubmed/21192829
publishDate 2010
dc.date.none.fl_str_mv 2010-12
2010-12-01T00:00:00Z
2011-01-08T01:23:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/657
url http://hdl.handle.net/10400.6/657
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1472-6963
DOI: 10.1186/1472-6963-10-349
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Jigisha Patel MRCP, PhD
publisher.none.fl_str_mv Jigisha Patel MRCP, PhD
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136327419035648

Registros relacionados