Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.6/657 |
Resumo: | http://www.ncbi.nlm.nih.gov/pubmed/21192829 |
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Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of PortugalHypertensionBlood pressureAntihypertensivesTreatmentControlPortugalhttp://www.ncbi.nlm.nih.gov/pubmed/21192829BACKGROUND: Interventions to improve blood pressure control in hypertension have had limited success in clinical practice despite evidence of cardiovascular disease prevention in randomised controlled trials. The objectives of this study were to evaluate blood pressure control and antihypertensive pharmacotherapy patterns in a population of Eastern Central Region of Portugal, attending a hospital outpatient clinic (ambulatory setting) for routine follow-up. METHODS: Medical data of all patients that attended at least two medical appointments of hypertension / dyslipidemia in a university hospital over a one and a half year period (from January 2008 to June 2009) were retrospectively analysed. Demographic variables, clinical data and blood pressure values of hypertensive patients included in the study, as well as prescribing metrics were examined on a descriptive basis and expressed as the mean +/- SD, frequency and percentages. Student's test and Mann-Whitney rank sum test were used to compare continuous variables and chi-square test and Fisher exact probability test were used to test for differences between categorical variables. RESULTS: In all, 37% of hypertensive patients (n=76) had their blood pressure controlled according to international guidelines. About 45.5% of patients with a target blood pressure <140/90 mmHg (n=156) were controlled, whereas in patients with diabetes or chronic kidney disease (n=49) the corresponding figure was only 10.2% (P<0.001). Among patients initiating hypertension / dyslipidemia consultation within the study period 32.1% had stage 2 hypertension in the first appointment, but this figure decreased to 3.6% in the last consultation (P=0.012). Thiazide-type diuretics were the most prescribed antihypertensive drugs (67%) followed by angiotensin receptor blockers (60%) and beta-blockers (43%). About 95.9% patients with comorbid diabetes were treated with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. CONCLUSIONS: Clinically important blood pressure decreases can be achieved soon after hypertension medical appointment initiation. However, many hypertensive patients prescribed with antihypertensive therapy fail to achieve blood pressure control in clinical practice, this control being worse among patients with diabetes or chronic kidney disease. As pharmacotherapy patterns seem to coincide with international guidelines, further research is needed to identify the causes of poor blood pressure control.This work was supported by Fundação para a Ciência e a Tecnologia (SFRH/BD/36756/2007) through a fellowship grant attributed to Manuel Morgado.Jigisha Patel MRCP, PhDuBibliorumMorgado, ManuelRolo, SandraPereira, LuísaSousa, Miguel Castelo-Branco Craveiro2011-01-08T01:23:32Z2010-122010-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/657eng1472-6963DOI: 10.1186/1472-6963-10-349info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:35:58Zoai:ubibliorum.ubi.pt:10400.6/657Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:42.350104Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
title |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
spellingShingle |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal Morgado, Manuel Hypertension Blood pressure Antihypertensives Treatment Control Portugal |
title_short |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
title_full |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
title_fullStr |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
title_full_unstemmed |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
title_sort |
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal |
author |
Morgado, Manuel |
author_facet |
Morgado, Manuel Rolo, Sandra Pereira, Luísa Sousa, Miguel Castelo-Branco Craveiro |
author_role |
author |
author2 |
Rolo, Sandra Pereira, Luísa Sousa, Miguel Castelo-Branco Craveiro |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
uBibliorum |
dc.contributor.author.fl_str_mv |
Morgado, Manuel Rolo, Sandra Pereira, Luísa Sousa, Miguel Castelo-Branco Craveiro |
dc.subject.por.fl_str_mv |
Hypertension Blood pressure Antihypertensives Treatment Control Portugal |
topic |
Hypertension Blood pressure Antihypertensives Treatment Control Portugal |
description |
http://www.ncbi.nlm.nih.gov/pubmed/21192829 |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12 2010-12-01T00:00:00Z 2011-01-08T01:23:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.6/657 |
url |
http://hdl.handle.net/10400.6/657 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1472-6963 DOI: 10.1186/1472-6963-10-349 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Jigisha Patel MRCP, PhD |
publisher.none.fl_str_mv |
Jigisha Patel MRCP, PhD |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799136327419035648 |