Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders
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Data de Publicação: | 2014 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316 |
Resumo: | Introduction: The author reviews the present indications of deep brain stimulation, its progress and outcomes, its targets and techniques, the main neurosurgeons and medical centers involved.Material and Methods: This review is based on the experience of the Functional Neurosurgery group of the Hospital Santa Maria (Centro Hospitalar de Lisboa Norte) since 1995 and on the bibliography published since 1980 indexed on PubMed.Results and Discussion: The deep brain stimulation applications in the different functional neurosciences fields are presented and discussed: Movement disorders, including Parkinson’s disease, dystonia and tremor, Gilles de la Tourette, chronic pain, epilepsy and psychosurgery with its different aims: Obsessive-compulsive disorder, severe resistant depression, resistant aggressiveness with disruptive behavior, eating behavior disorders (anorexia nervosa, morbid obesity) and drug addiction (alcohol, opioids, cocaine).Conclusions: In most of these clinical situations, deep brain stimulation is a safe and useful therapeutic resource that must be considered whenever the usual therapies are useless or not enough; in the other cases a greater experience is needed to make it a regular indication.Keywords: Deep Brain Stimulation; Parkinson Disease; Dystonia; Tremor; Epilepsy; Psychosurgery; Central Nervous System Diseases. |
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Deep Brain Stimulation: New Frontier in the Treatment of CNS DisordersEstimulação Cerebral Profunda: Nova Fronteira no Tratamento das Doenças do Sistema Nervoso CentralIntroduction: The author reviews the present indications of deep brain stimulation, its progress and outcomes, its targets and techniques, the main neurosurgeons and medical centers involved.Material and Methods: This review is based on the experience of the Functional Neurosurgery group of the Hospital Santa Maria (Centro Hospitalar de Lisboa Norte) since 1995 and on the bibliography published since 1980 indexed on PubMed.Results and Discussion: The deep brain stimulation applications in the different functional neurosciences fields are presented and discussed: Movement disorders, including Parkinson’s disease, dystonia and tremor, Gilles de la Tourette, chronic pain, epilepsy and psychosurgery with its different aims: Obsessive-compulsive disorder, severe resistant depression, resistant aggressiveness with disruptive behavior, eating behavior disorders (anorexia nervosa, morbid obesity) and drug addiction (alcohol, opioids, cocaine).Conclusions: In most of these clinical situations, deep brain stimulation is a safe and useful therapeutic resource that must be considered whenever the usual therapies are useless or not enough; in the other cases a greater experience is needed to make it a regular indication.Keywords: Deep Brain Stimulation; Parkinson Disease; Dystonia; Tremor; Epilepsy; Psychosurgery; Central Nervous System Diseases.Introdução: O autor faz uma revisão das indicações atuais da estimulação cerebral profunda, dos seus desenvolvimentos e resultados, dos alvos e técnicas utilizados, dos principais neurocirurgiões e centros médicos envolvidos.Material e Métodos: Esta revisão é baseada na experiência do grupo de Neurocirurgia Funcional do Hospital de Santa Maria (Centro Hospitalar Lisboa Norte) desde 1995 e na revisão bibliográfica dos artigos publicados sobre esta matéria desde 1980 indexados na PubMed.Resultados e Discussão: São apresentadas e discutidas as aplicações da estimulação cerebral profunda nos diferentes domínios das neurociências funcionais: Doenças do Movimento, incluindo doença de Parkinson, distonias e tremores, síndrome de Gilles de la Tourette, dor crónica, epilepsia e psicocirurgia nas múltiplas áreas que esta compreende: perturbação obsessiva-compulsiva, depressão grave refratária, comportamento disruptivo com agressividade intratável, deterioração da memória e demência, perturbações do comportamento alimentar (anorexia nervosa, obesidade mórbida) e toxicodependências refratárias (álcool, opioides, cocaína).Conclusões: Na maioria das situações clínicas referidas a estimulação cerebral profunda constitui um recurso terapêutico seguro e eficaz a ter em consideração quando as terapias habituais se mostram insuficientes; nos restantes casos há que reunir maior experiência até adotar o seu uso regular.Palavras-chave: Estimulação Cerebral Profunda; Doença de Parkinson; Distonia; Tremor; Epilepsia; Psicocirurgia; Doenças do Sistema Nervoso Central.Ordem dos Médicos2014-09-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdftext/htmlimage/jpegimage/jpegimage/jpegimage/jpegimage/jpeghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316oai:ojs.www.actamedicaportuguesa.com:article/5316Acta Médica Portuguesa; Vol. 27 No. 5 (2014): September-October; 641-648Acta Médica Portuguesa; Vol. 27 N.º 5 (2014): Setembro-Outubro; 641-6481646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/4083https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/4099https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7316https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7317https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7318https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7319https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7421Gonçalves Ferreira, Antonioinfo:eu-repo/semantics/openAccess2022-12-20T11:04:18Zoai:ojs.www.actamedicaportuguesa.com:article/5316Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:04.203894Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders Estimulação Cerebral Profunda: Nova Fronteira no Tratamento das Doenças do Sistema Nervoso Central |
title |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
spellingShingle |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders Gonçalves Ferreira, Antonio |
title_short |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
title_full |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
title_fullStr |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
title_full_unstemmed |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
title_sort |
Deep Brain Stimulation: New Frontier in the Treatment of CNS Disorders |
author |
Gonçalves Ferreira, Antonio |
author_facet |
Gonçalves Ferreira, Antonio |
author_role |
author |
dc.contributor.author.fl_str_mv |
Gonçalves Ferreira, Antonio |
description |
Introduction: The author reviews the present indications of deep brain stimulation, its progress and outcomes, its targets and techniques, the main neurosurgeons and medical centers involved.Material and Methods: This review is based on the experience of the Functional Neurosurgery group of the Hospital Santa Maria (Centro Hospitalar de Lisboa Norte) since 1995 and on the bibliography published since 1980 indexed on PubMed.Results and Discussion: The deep brain stimulation applications in the different functional neurosciences fields are presented and discussed: Movement disorders, including Parkinson’s disease, dystonia and tremor, Gilles de la Tourette, chronic pain, epilepsy and psychosurgery with its different aims: Obsessive-compulsive disorder, severe resistant depression, resistant aggressiveness with disruptive behavior, eating behavior disorders (anorexia nervosa, morbid obesity) and drug addiction (alcohol, opioids, cocaine).Conclusions: In most of these clinical situations, deep brain stimulation is a safe and useful therapeutic resource that must be considered whenever the usual therapies are useless or not enough; in the other cases a greater experience is needed to make it a regular indication.Keywords: Deep Brain Stimulation; Parkinson Disease; Dystonia; Tremor; Epilepsy; Psychosurgery; Central Nervous System Diseases. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-09-25 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316 oai:ojs.www.actamedicaportuguesa.com:article/5316 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316 |
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oai:ojs.www.actamedicaportuguesa.com:article/5316 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/4083 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/4099 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7316 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7317 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7318 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7319 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5316/7421 |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 27 No. 5 (2014): September-October; 641-648 Acta Médica Portuguesa; Vol. 27 N.º 5 (2014): Setembro-Outubro; 641-648 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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