Factors associated with willingness to donate embryos for research among couples undergoing IVF

• Autor(a) principal: Samorinha, Catarina
• Data de Publicação: 2016
• Outros Autores: Severo, Milton, Alves, Elisabete, Machado, Helena, Figueiredo, Bárbara, Silva, Susana
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10316/36314; https://doi.org/10.1016/j.rbmo.2015.11.018
• topic: Adult; Anxiety; Cross-Sectional Studies; Cryopreservation; Embryo Disposition; Embryo, Mammalian; Ethics, Medical; Female; Fertilization in Vitro; Humans; Infertility; Male; Patient-Centered Care; Portugal; Religion; Sex Factors; Surveys and Questionnaires; Tissue Donors; Decision Making; Embryo Research

Between 2011 and 2012, 213 heterosexual couples undergoing fertility treatments in a Portuguese public fertility centre were systematically recruited to assess factors associated with willingness to donate embryos for research. Data were collected by questionnaire. Most couples (87.3%; 95% CI 82.1 to 91.5) were willing to donate embryos for research, citing benefits for science, health and infertile patients. Almost all couples (94.3%; 95% CI 89.8 to 96.7) reached consensus about the decision. Willingness to donate was more frequent in women younger than 36 years (adjusted OR 3.06; 95% CI 1.23 to 7.61) and who considered embryo research to be very important (adjusted OR: 6.32; 95% CI 1.85 to 21.64), and in Catholic men (adjusted OR 4.16; 95% CI 1.53 to 11.30). Those unwilling to donate reported conceptualizing embryos as children or living beings and a lack of information or fears about embryo research. Men with higher levels of trait anxiety (adjusted OR 0.90; 95% CI 0.84 to 0.96) were less frequently willing to donate. Future research on embryo disposition decision-making should include the assessment of gender differences and psychosocial factors. Ethically robust policies and accurate information about the results of human embryo research are required.