Ochratoxin A in nephropathic patients from two cities of central zone in Portugal
Autor(a) principal: | |
---|---|
Data de Publicação: | 2007 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/5857 https://doi.org/10.1016/j.jpba.2006.12.001 |
Resumo: | Ochratoxin A (OTA) produced by Aspergillus and Penicilliumgenera contaminates several foods. OTA is nephrotoxic to all animal species studied so far, and most likely to humans, who show the longest half-life for elimination of this toxin among all examined species. OTA has other toxic effects such as teratogenicity, immunotoxiity, genotoxicity, and is also mutagenic and carcinogenic, all of which lead to life-threatening pathologies through several molecular pathways. |
id |
RCAP_ed9aaa1aaf1a9e14f30a76af6baba334 |
---|---|
oai_identifier_str |
oai:estudogeral.uc.pt:10316/5857 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Ochratoxin A in nephropathic patients from two cities of central zone in PortugalOchratoxin AHPLC-spectrofluorimeterHuman serumCoimbraOchratoxin A (OTA) produced by Aspergillus and Penicilliumgenera contaminates several foods. OTA is nephrotoxic to all animal species studied so far, and most likely to humans, who show the longest half-life for elimination of this toxin among all examined species. OTA has other toxic effects such as teratogenicity, immunotoxiity, genotoxicity, and is also mutagenic and carcinogenic, all of which lead to life-threatening pathologies through several molecular pathways.http://www.sciencedirect.com/science/article/B6TGX-4MS9JXF-2/1/6c0f4b2a3b77c84ec1f89cdefb65913c2007info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/5857http://hdl.handle.net/10316/5857https://doi.org/10.1016/j.jpba.2006.12.001engJournal of Pharmaceutical and Biomedical Analysis. 44:2 (2007) 553-557Dinis, A. M. P.Lino, C. M.Pena, A. S.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:49:11Zoai:estudogeral.uc.pt:10316/5857Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:47:22.861509Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
title |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
spellingShingle |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal Dinis, A. M. P. Ochratoxin A HPLC-spectrofluorimeter Human serum Coimbra |
title_short |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
title_full |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
title_fullStr |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
title_full_unstemmed |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
title_sort |
Ochratoxin A in nephropathic patients from two cities of central zone in Portugal |
author |
Dinis, A. M. P. |
author_facet |
Dinis, A. M. P. Lino, C. M. Pena, A. S. |
author_role |
author |
author2 |
Lino, C. M. Pena, A. S. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Dinis, A. M. P. Lino, C. M. Pena, A. S. |
dc.subject.por.fl_str_mv |
Ochratoxin A HPLC-spectrofluorimeter Human serum Coimbra |
topic |
Ochratoxin A HPLC-spectrofluorimeter Human serum Coimbra |
description |
Ochratoxin A (OTA) produced by Aspergillus and Penicilliumgenera contaminates several foods. OTA is nephrotoxic to all animal species studied so far, and most likely to humans, who show the longest half-life for elimination of this toxin among all examined species. OTA has other toxic effects such as teratogenicity, immunotoxiity, genotoxicity, and is also mutagenic and carcinogenic, all of which lead to life-threatening pathologies through several molecular pathways. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/5857 http://hdl.handle.net/10316/5857 https://doi.org/10.1016/j.jpba.2006.12.001 |
url |
http://hdl.handle.net/10316/5857 https://doi.org/10.1016/j.jpba.2006.12.001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Pharmaceutical and Biomedical Analysis. 44:2 (2007) 553-557 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
aplication/PDF |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133751119183872 |