Estimated cancer risks attributable to radiation dose in ureteral stenting procedures

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Tiago
Data de Publicação: 2008
Outros Autores: Martins, Cláudia, Rocha, Marta
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25758/set.44
Resumo: Introduction: Double-J ureteral stenting is a frequent interventional urological procedure that implicates the use of x-ray fluoroscopy, with considerable exposure times, incident in an anatomic region with several organs. This fact raises doubts about the patient risks attributed to radiation dose. The purpose of this study was to clarify these doubts in estimating the cancer risk inherent to the patient's effective dose. Method: We studied specific data of 146 patients submitted to ureteral stenting procedures in the Urologic Department of Hospital Santa Maria. Effective doses were determined with a computational Monte Carlo-based program. Cancer risks were estimated with probability coefficients considering the linear non-threshold dose-effect relation (LNT) of the low doses of radiation. Results: A patient submitted to a ureteral stent insertion followed by a removal procedure, develops an increased cancer risk of 0,012%. This means that 1 in 8330 patients develops radiation-induced cancer. Also, a patient submitted to a ureteral stent insertion followed by 1 substitution, and a removal procedure is submitted to a mean effective dose of 4,47 mSv. This value is similar to the effective dose of an abdominal TC. Conclusion: When we compare the radiation risks with the clinical benefit, of “saving” renal function, we can conclude that benefits are greatly more important than risks. Furthermore, we verify that, although low, there is always some risk attributed to radiation dose. Thus, dose optimization and clinical justification should always be considered in these procedures.
id RCAP_eeaeec7fb4558f91aae963c5b5f37e7e
oai_identifier_str oai:journals.ipl.pt:article/766
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Estimated cancer risks attributable to radiation dose in ureteral stenting proceduresEstimativa do risco de carcinogénese associado à radiação X no cateterismo ureteral “duplo J”Cateterismo ureteralRadiação XDoseRiscoCarcinogéneseUreteral stentingX-rayDoseRiskCancerIntroduction: Double-J ureteral stenting is a frequent interventional urological procedure that implicates the use of x-ray fluoroscopy, with considerable exposure times, incident in an anatomic region with several organs. This fact raises doubts about the patient risks attributed to radiation dose. The purpose of this study was to clarify these doubts in estimating the cancer risk inherent to the patient's effective dose. Method: We studied specific data of 146 patients submitted to ureteral stenting procedures in the Urologic Department of Hospital Santa Maria. Effective doses were determined with a computational Monte Carlo-based program. Cancer risks were estimated with probability coefficients considering the linear non-threshold dose-effect relation (LNT) of the low doses of radiation. Results: A patient submitted to a ureteral stent insertion followed by a removal procedure, develops an increased cancer risk of 0,012%. This means that 1 in 8330 patients develops radiation-induced cancer. Also, a patient submitted to a ureteral stent insertion followed by 1 substitution, and a removal procedure is submitted to a mean effective dose of 4,47 mSv. This value is similar to the effective dose of an abdominal TC. Conclusion: When we compare the radiation risks with the clinical benefit, of “saving” renal function, we can conclude that benefits are greatly more important than risks. Furthermore, we verify that, although low, there is always some risk attributed to radiation dose. Thus, dose optimization and clinical justification should always be considered in these procedures.Introdução: Porque o cateterismo ureteral “duplo J” implica a exposição do doente a radiação X, com tempos de exposição consideráveis, incidentes numa região anatómica constituída por diversos órgãos, existem dúvidas em relação aos riscos associados à dose de radiação acumulada pelos doentes. O objectivo deste trabalho centrou-se em clarificar estas dúvidas através da estimação quantitativa do risco de carcinogénese associado à dose de radiação. Método: Foram estudados dados relativos a 146 doentes submetidos a procedimentos de cateterismo ureteral “duplo J” no Serviço de Urologia do Hospital de Santa Maria (HSM). As doses eficazes foram determinadas através de métodos Monte Carlo. O risco de carcinogénese foi estimado com base na relação linear dose/efeito, sem limiar de dose, por coeficientes de probabilidade. Resultados: Como resultados mais relevantes, estimou-se que 1 colocação seguida de 1 extracção do cateter “duplo J” proporciona ao doente um risco acrescido de carcinogénese de 0,012%, ou seja, cerca de 1 doente em 8330 desenvolve cancro radio-‑induzido. Estima-se também, por exemplo, que um doente submetido a 1 colocação, 1 substituição e 1 extracção é, em média, submetido a uma dose eficaz de 4,47mSv, valor de dose semelhante ao proporcionado por uma TC abdominal. Conclusão: Quando comparamos os riscos associados à radiação com o benefício clínico de “poupar” a função renal, concluímos que os benefícios são inestimavelmente mais importantes que os riscos. De qualquer forma, verificamos que existe sempre, ainda que relativamente baixo, algum risco associado aos níveis de dose. Assim, os princípios da Justificação e da Optimização deverão ser sempre equacionados neste tipo de procedimentos.Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)2008-04-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25758/set.44https://doi.org/10.25758/set.44Saúde e Tecnologia; No. 01 (2008): Maio 2008; 30-35Saúde & Tecnologia; N.º 01 (2008): Maio 2008; 30-351646-9704reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://journals.ipl.pt/stecnologia/article/view/766https://journals.ipl.pt/stecnologia/article/view/766/656Direitos de Autor (c) 2023 Saúde & Tecnologiainfo:eu-repo/semantics/openAccessRibeiro, TiagoMartins, CláudiaRocha, Marta2023-05-26T08:30:13Zoai:journals.ipl.pt:article/766Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:56:04.260404Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
Estimativa do risco de carcinogénese associado à radiação X no cateterismo ureteral “duplo J”
title Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
spellingShingle Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
Ribeiro, Tiago
Cateterismo ureteral
Radiação X
Dose
Risco
Carcinogénese
Ureteral stenting
X-ray
Dose
Risk
Cancer
title_short Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
title_full Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
title_fullStr Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
title_full_unstemmed Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
title_sort Estimated cancer risks attributable to radiation dose in ureteral stenting procedures
author Ribeiro, Tiago
author_facet Ribeiro, Tiago
Martins, Cláudia
Rocha, Marta
author_role author
author2 Martins, Cláudia
Rocha, Marta
author2_role author
author
dc.contributor.author.fl_str_mv Ribeiro, Tiago
Martins, Cláudia
Rocha, Marta
dc.subject.por.fl_str_mv Cateterismo ureteral
Radiação X
Dose
Risco
Carcinogénese
Ureteral stenting
X-ray
Dose
Risk
Cancer
topic Cateterismo ureteral
Radiação X
Dose
Risco
Carcinogénese
Ureteral stenting
X-ray
Dose
Risk
Cancer
description Introduction: Double-J ureteral stenting is a frequent interventional urological procedure that implicates the use of x-ray fluoroscopy, with considerable exposure times, incident in an anatomic region with several organs. This fact raises doubts about the patient risks attributed to radiation dose. The purpose of this study was to clarify these doubts in estimating the cancer risk inherent to the patient's effective dose. Method: We studied specific data of 146 patients submitted to ureteral stenting procedures in the Urologic Department of Hospital Santa Maria. Effective doses were determined with a computational Monte Carlo-based program. Cancer risks were estimated with probability coefficients considering the linear non-threshold dose-effect relation (LNT) of the low doses of radiation. Results: A patient submitted to a ureteral stent insertion followed by a removal procedure, develops an increased cancer risk of 0,012%. This means that 1 in 8330 patients develops radiation-induced cancer. Also, a patient submitted to a ureteral stent insertion followed by 1 substitution, and a removal procedure is submitted to a mean effective dose of 4,47 mSv. This value is similar to the effective dose of an abdominal TC. Conclusion: When we compare the radiation risks with the clinical benefit, of “saving” renal function, we can conclude that benefits are greatly more important than risks. Furthermore, we verify that, although low, there is always some risk attributed to radiation dose. Thus, dose optimization and clinical justification should always be considered in these procedures.
publishDate 2008
dc.date.none.fl_str_mv 2008-04-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25758/set.44
https://doi.org/10.25758/set.44
url https://doi.org/10.25758/set.44
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://journals.ipl.pt/stecnologia/article/view/766
https://journals.ipl.pt/stecnologia/article/view/766/656
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2023 Saúde & Tecnologia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2023 Saúde & Tecnologia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)
publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)
dc.source.none.fl_str_mv Saúde e Tecnologia; No. 01 (2008): Maio 2008; 30-35
Saúde & Tecnologia; N.º 01 (2008): Maio 2008; 30-35
1646-9704
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799131636182286336