Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage

Detalhes bibliográficos
Autor(a) principal: Oliveira, AS
Data de Publicação: 2019
Outros Autores: Seidi, O, Ribeiro, NA, Colaço, R, Serro, AP
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/31690
Resumo: Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.
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spelling Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human CartilageCartilage, ArticularHydrogelsCartilagem ArticularHidrogéisDesigning materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.Repositório ComumOliveira, ASSeidi, ORibeiro, NAColaço, RSerro, AP2020-03-11T21:37:25Z2019-10-182019-10-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/31690engMaterials (Basel). 2019 Oct 18;12(20). pii: E3413.10.3390/ma12203413info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-25T04:45:56Zoai:comum.rcaap.pt:10400.26/31690Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:09:30.486418Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
title Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
spellingShingle Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
Oliveira, AS
Cartilage, Articular
Hydrogels
Cartilagem Articular
Hidrogéis
title_short Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
title_full Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
title_fullStr Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
title_full_unstemmed Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
title_sort Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
author Oliveira, AS
author_facet Oliveira, AS
Seidi, O
Ribeiro, NA
Colaço, R
Serro, AP
author_role author
author2 Seidi, O
Ribeiro, NA
Colaço, R
Serro, AP
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Oliveira, AS
Seidi, O
Ribeiro, NA
Colaço, R
Serro, AP
dc.subject.por.fl_str_mv Cartilage, Articular
Hydrogels
Cartilagem Articular
Hidrogéis
topic Cartilage, Articular
Hydrogels
Cartilagem Articular
Hidrogéis
description Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-18
2019-10-18T00:00:00Z
2020-03-11T21:37:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/31690
url http://hdl.handle.net/10400.26/31690
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials (Basel). 2019 Oct 18;12(20). pii: E3413.
10.3390/ma12203413
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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