Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/31690 |
Resumo: | Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones. |
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Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human CartilageCartilage, ArticularHydrogelsCartilagem ArticularHidrogéisDesigning materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.Repositório ComumOliveira, ASSeidi, ORibeiro, NAColaço, RSerro, AP2020-03-11T21:37:25Z2019-10-182019-10-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/31690engMaterials (Basel). 2019 Oct 18;12(20). pii: E3413.10.3390/ma12203413info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-25T04:45:56Zoai:comum.rcaap.pt:10400.26/31690Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:09:30.486418Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
spellingShingle |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage Oliveira, AS Cartilage, Articular Hydrogels Cartilagem Articular Hidrogéis |
title_short |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_full |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_fullStr |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_full_unstemmed |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_sort |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
author |
Oliveira, AS |
author_facet |
Oliveira, AS Seidi, O Ribeiro, NA Colaço, R Serro, AP |
author_role |
author |
author2 |
Seidi, O Ribeiro, NA Colaço, R Serro, AP |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Oliveira, AS Seidi, O Ribeiro, NA Colaço, R Serro, AP |
dc.subject.por.fl_str_mv |
Cartilage, Articular Hydrogels Cartilagem Articular Hidrogéis |
topic |
Cartilage, Articular Hydrogels Cartilagem Articular Hidrogéis |
description |
Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-18 2019-10-18T00:00:00Z 2020-03-11T21:37:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/31690 |
url |
http://hdl.handle.net/10400.26/31690 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials (Basel). 2019 Oct 18;12(20). pii: E3413. 10.3390/ma12203413 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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