An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004 |
Resumo: | Background Residual Renal Function (RRF) preservation is related to survival in Peritoneal Dialysis (PD) patients. The effect of different PD modalities on RRF is unclear. Objectives: To analyse the evolution of RRF function in patients in PD, maintained with automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD), and study other possible factors related to RRF decline. Methods: A single-centre retrospective study with 104 incident PD patients (48 CAPD and 56 APD). Patients with no RRF function at PD beginning were excluded. The mean age was 52.1±16 years, 70% were male and 16% diabetics. Thirteen patients used low glucose degradation product (GDP) solutions and 57 patients were using icodextrin. The use of diuretics, angiotensinconverting enzyme inhibitors and angiotensin II receptor blockers was also analysed. RRF and diuresis were analysed every 3 months and peritoneal transport every 6 months, forl a total of 48 months. The mean follow-up was 29.3±19 months. Results: CAPD patients were older, had higher prevalence of diabetes, used less icodextrin and more low GDP solutions and were followed for a longer time. No significant differences in RRF were observed in either modality in basal or during the follow-up: RRF at 24 months with 3.67±3.5ml/min in CAPD patients and 3.82±2.5ml/min in APD patients; or in diuresis: 883±807ml/day and 1333±905ml/day respectively. Neither group showed significant differences in peritoneal transport parameters over time. The use of icodextrin was related to a higher diuresis preservation at 24 months: 1519±1035ml/day in patients using icodextrin and 767±633ml/day in patients without icodextrin (p=0.01). No differences were found in RRF evolution in either group. Conclusions: We conclude that DP modality does not influence either the RRF function or diuresis outcomes or peritoneal transport parameters. The initial use of icodextrin was related to better diuresis preservation without changes in RRF |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal FunctionBackground Residual Renal Function (RRF) preservation is related to survival in Peritoneal Dialysis (PD) patients. The effect of different PD modalities on RRF is unclear. Objectives: To analyse the evolution of RRF function in patients in PD, maintained with automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD), and study other possible factors related to RRF decline. Methods: A single-centre retrospective study with 104 incident PD patients (48 CAPD and 56 APD). Patients with no RRF function at PD beginning were excluded. The mean age was 52.1±16 years, 70% were male and 16% diabetics. Thirteen patients used low glucose degradation product (GDP) solutions and 57 patients were using icodextrin. The use of diuretics, angiotensinconverting enzyme inhibitors and angiotensin II receptor blockers was also analysed. RRF and diuresis were analysed every 3 months and peritoneal transport every 6 months, forl a total of 48 months. The mean follow-up was 29.3±19 months. Results: CAPD patients were older, had higher prevalence of diabetes, used less icodextrin and more low GDP solutions and were followed for a longer time. No significant differences in RRF were observed in either modality in basal or during the follow-up: RRF at 24 months with 3.67±3.5ml/min in CAPD patients and 3.82±2.5ml/min in APD patients; or in diuresis: 883±807ml/day and 1333±905ml/day respectively. Neither group showed significant differences in peritoneal transport parameters over time. The use of icodextrin was related to a higher diuresis preservation at 24 months: 1519±1035ml/day in patients using icodextrin and 767±633ml/day in patients without icodextrin (p=0.01). No differences were found in RRF evolution in either group. Conclusions: We conclude that DP modality does not influence either the RRF function or diuresis outcomes or peritoneal transport parameters. The initial use of icodextrin was related to better diuresis preservation without changes in RRFSociedade Portuguesa de Nefrologia2016-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004Portuguese Journal of Nephrology & Hypertension v.30 n.4 2016reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004Candido,Cristinadel Peso,GloriaCarreño,GildaSantacruz,JuanSánchez-Villanueva,RafaelAguilar,AnaRodriguez-Gayo,LucíaSelgas,RafaelBajo,Mª Auxiliadorainfo:eu-repo/semantics/openAccess2024-02-06T17:04:53Zoai:scielo:S0872-01692016000400004Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:18:57.461577Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
title |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
spellingShingle |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function Candido,Cristina |
title_short |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
title_full |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
title_fullStr |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
title_full_unstemmed |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
title_sort |
An Automated Peritoneal Dialysis regimen is not detrimental to Residual Renal Function |
author |
Candido,Cristina |
author_facet |
Candido,Cristina del Peso,Gloria Carreño,Gilda Santacruz,Juan Sánchez-Villanueva,Rafael Aguilar,Ana Rodriguez-Gayo,Lucía Selgas,Rafael Bajo,Mª Auxiliadora |
author_role |
author |
author2 |
del Peso,Gloria Carreño,Gilda Santacruz,Juan Sánchez-Villanueva,Rafael Aguilar,Ana Rodriguez-Gayo,Lucía Selgas,Rafael Bajo,Mª Auxiliadora |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Candido,Cristina del Peso,Gloria Carreño,Gilda Santacruz,Juan Sánchez-Villanueva,Rafael Aguilar,Ana Rodriguez-Gayo,Lucía Selgas,Rafael Bajo,Mª Auxiliadora |
description |
Background Residual Renal Function (RRF) preservation is related to survival in Peritoneal Dialysis (PD) patients. The effect of different PD modalities on RRF is unclear. Objectives: To analyse the evolution of RRF function in patients in PD, maintained with automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD), and study other possible factors related to RRF decline. Methods: A single-centre retrospective study with 104 incident PD patients (48 CAPD and 56 APD). Patients with no RRF function at PD beginning were excluded. The mean age was 52.1±16 years, 70% were male and 16% diabetics. Thirteen patients used low glucose degradation product (GDP) solutions and 57 patients were using icodextrin. The use of diuretics, angiotensinconverting enzyme inhibitors and angiotensin II receptor blockers was also analysed. RRF and diuresis were analysed every 3 months and peritoneal transport every 6 months, forl a total of 48 months. The mean follow-up was 29.3±19 months. Results: CAPD patients were older, had higher prevalence of diabetes, used less icodextrin and more low GDP solutions and were followed for a longer time. No significant differences in RRF were observed in either modality in basal or during the follow-up: RRF at 24 months with 3.67±3.5ml/min in CAPD patients and 3.82±2.5ml/min in APD patients; or in diuresis: 883±807ml/day and 1333±905ml/day respectively. Neither group showed significant differences in peritoneal transport parameters over time. The use of icodextrin was related to a higher diuresis preservation at 24 months: 1519±1035ml/day in patients using icodextrin and 767±633ml/day in patients without icodextrin (p=0.01). No differences were found in RRF evolution in either group. Conclusions: We conclude that DP modality does not influence either the RRF function or diuresis outcomes or peritoneal transport parameters. The initial use of icodextrin was related to better diuresis preservation without changes in RRF |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-12-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692016000400004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
dc.source.none.fl_str_mv |
Portuguese Journal of Nephrology & Hypertension v.30 n.4 2016 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137279636144128 |