Neurosensory detachment in acute myeloid leukemia
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.48560/rspo.19598 |
Resumo: | Neurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary. |
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Neurosensory detachment in acute myeloid leukemiaComunicações Curtas e Imagens em OftalmologiaNeurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary.O descolamento da retina neurosensorial é um achado raro em doentes com diagnóstico de leucemia mielóide aguda. Descrevemos um caso clínico de uma doente com 25 anos de idade, antecedentes pessoais de leucemia mielóide aguda sob quimioterapia, referenciada ao Departamento de Oftalmologia por visão turva e metamorfopsias no olho esquerdo com duas semanas de evolução. Ao exame oftalmológico, o olho direito não apresentou alterações e no olho esquerdo observou-se uma lesão paracentral, elevada, oval, superior à macula com uma pequena hemorragia adjacente. Foram realizados exames complementares de diagnóstico, dos quais se destacam: tomografia de coerência óptica macular com evidência de um descolamento neurosensorial e edema macular, angiografia fluoresceínica que mostrou uma hiperfluorescência com difusão multifocal e angiografia com verde indocianina que demonstrou uma área hipofluorescente sugerindo isquémia coroideia. Foi realizado o diagnóstico de descolamento neurosensorial por infiltração coroideia subjacente. A doente manteve a quimioterapia, após um mês, o descolamento neurosensorial desapareceu e a acuidade visual foi de 20/20. Este caso evidencia uma apresentação ocular rara de uma doença sistémica e demonstra a importância de uma abordagem multidisciplinar.Ajnet2020-10-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporthttps://doi.org/10.48560/rspo.19598eng1646-69501646-6950Lopes, Patrícia José FigueiredoLeal, InêsMarques-Neves, Carlos Marques-NevesPinto Ferreira, Nunoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-22T17:06:11Zoai:ojs.revistas.rcaap.pt:article/19598Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:01:44.001357Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Neurosensory detachment in acute myeloid leukemia |
title |
Neurosensory detachment in acute myeloid leukemia |
spellingShingle |
Neurosensory detachment in acute myeloid leukemia Lopes, Patrícia José Figueiredo Comunicações Curtas e Imagens em Oftalmologia |
title_short |
Neurosensory detachment in acute myeloid leukemia |
title_full |
Neurosensory detachment in acute myeloid leukemia |
title_fullStr |
Neurosensory detachment in acute myeloid leukemia |
title_full_unstemmed |
Neurosensory detachment in acute myeloid leukemia |
title_sort |
Neurosensory detachment in acute myeloid leukemia |
author |
Lopes, Patrícia José Figueiredo |
author_facet |
Lopes, Patrícia José Figueiredo Leal, Inês Marques-Neves, Carlos Marques-Neves Pinto Ferreira, Nuno |
author_role |
author |
author2 |
Leal, Inês Marques-Neves, Carlos Marques-Neves Pinto Ferreira, Nuno |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Lopes, Patrícia José Figueiredo Leal, Inês Marques-Neves, Carlos Marques-Neves Pinto Ferreira, Nuno |
dc.subject.por.fl_str_mv |
Comunicações Curtas e Imagens em Oftalmologia |
topic |
Comunicações Curtas e Imagens em Oftalmologia |
description |
Neurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-21T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.48560/rspo.19598 |
url |
https://doi.org/10.48560/rspo.19598 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1646-6950 1646-6950 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Ajnet |
publisher.none.fl_str_mv |
Ajnet |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130482639634432 |