Neurosensory detachment in acute myeloid leukemia

Detalhes bibliográficos
Autor(a) principal: Lopes, Patrícia José Figueiredo
Data de Publicação: 2020
Outros Autores: Leal, Inês, Marques-Neves, Carlos Marques-Neves, Pinto Ferreira, Nuno
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48560/rspo.19598
Resumo: Neurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary.
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spelling Neurosensory detachment in acute myeloid leukemiaComunicações Curtas e Imagens em OftalmologiaNeurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary.O descolamento da retina neurosensorial é um achado raro em doentes com diagnóstico de leucemia mielóide aguda. Descrevemos um caso clínico de uma doente com 25 anos de idade, antecedentes pessoais de leucemia mielóide aguda sob quimioterapia, referenciada ao Departamento de Oftalmologia por visão turva e metamorfopsias no olho esquerdo com duas semanas de evolução. Ao exame oftalmológico, o olho direito não apresentou alterações e no olho esquerdo observou-se uma lesão paracentral, elevada, oval, superior à macula com uma pequena hemorragia adjacente. Foram realizados exames complementares de diagnóstico, dos quais se destacam: tomografia de coerência óptica macular com evidência de um descolamento neurosensorial e edema macular, angiografia fluoresceínica que mostrou uma hiperfluorescência com difusão multifocal e angiografia com verde indocianina que demonstrou uma área hipofluorescente sugerindo isquémia coroideia. Foi realizado o diagnóstico de descolamento neurosensorial por infiltração coroideia subjacente. A doente manteve a quimioterapia, após um mês, o descolamento neurosensorial desapareceu e a acuidade visual foi de 20/20. Este caso evidencia uma apresentação ocular rara de uma doença sistémica e demonstra a importância de uma abordagem multidisciplinar.Ajnet2020-10-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporthttps://doi.org/10.48560/rspo.19598eng1646-69501646-6950Lopes, Patrícia José FigueiredoLeal, InêsMarques-Neves, Carlos Marques-NevesPinto Ferreira, Nunoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-22T17:06:11Zoai:ojs.revistas.rcaap.pt:article/19598Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:01:44.001357Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Neurosensory detachment in acute myeloid leukemia
title Neurosensory detachment in acute myeloid leukemia
spellingShingle Neurosensory detachment in acute myeloid leukemia
Lopes, Patrícia José Figueiredo
Comunicações Curtas e Imagens em Oftalmologia
title_short Neurosensory detachment in acute myeloid leukemia
title_full Neurosensory detachment in acute myeloid leukemia
title_fullStr Neurosensory detachment in acute myeloid leukemia
title_full_unstemmed Neurosensory detachment in acute myeloid leukemia
title_sort Neurosensory detachment in acute myeloid leukemia
author Lopes, Patrícia José Figueiredo
author_facet Lopes, Patrícia José Figueiredo
Leal, Inês
Marques-Neves, Carlos Marques-Neves
Pinto Ferreira, Nuno
author_role author
author2 Leal, Inês
Marques-Neves, Carlos Marques-Neves
Pinto Ferreira, Nuno
author2_role author
author
author
dc.contributor.author.fl_str_mv Lopes, Patrícia José Figueiredo
Leal, Inês
Marques-Neves, Carlos Marques-Neves
Pinto Ferreira, Nuno
dc.subject.por.fl_str_mv Comunicações Curtas e Imagens em Oftalmologia
topic Comunicações Curtas e Imagens em Oftalmologia
description Neurosensory retinal detachment is a rare ocular finding in acute myeloid leukemia. We describe a case of a 25 year-old female with history of acute myeloid leukemia under chemotherapy that was referred to the Ophthalmology Department due to blurred vision and metamorphopsia in the left eye for the last two weeks. On examination, there was an oval, high, paracentral lesion, superior to the macula with adjacent small hemorrhage. She performed macular spectral domain optic coherence tomography that showed macular edema with neurosensory detachment, fluorescein angiography that revealed a multifocal diffusion with hyperfluorescence and indocyanine green hypofluorescent spots suggesting choroidal ischemia. A diagnosis of neurosensorial retinal detachment that revealed a choroidal infiltration was made. The chemotherapy was continued and, one month after, progressive visual improvement was identified. A systemic disease with atypical retinal findings should alert to diagnose extramedullary disease and a multidisciplinary approach is necessary.
publishDate 2020
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