Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/109693 https://doi.org/10.3390/toxics2020188 |
Resumo: | Antibiotics represent a pharmacotherapeutic group widely used in both human and veterinary medicine for which ecosurveillance has been continually recommended. It is urgent to rank the antibiotics and highlight those that may pose potential risk to the environment, a key step for the risk management. The absence of this type of contributions applied to the Portuguese reality supported the idea of compiling the data presented herein. With such purpose the most recent and representative data is used to draw a comparative contribution of each antimicrobial classes according to their intended use, i.e., in human versus veterinary medicine. The aim was to assess: (1) the amount and patterns of antimicrobials usage between human and animals; (2) the qualitative comparison between the antimicrobial classes used in each practice (human and veterinary) or specific use; (3) the potential to enter the environment, metabolism, mode of action and environmental occurrences. This manuscript will, thus, identify priorities for the environmental risk assessment, considering the ranking of the antimicrobials by their usage and potential environmental exposure. Ultimately, this study will serve as a basis for future monitoring programs, guiding the policy of regulatory agencies. |
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Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillanceantibioticsconsumptionecosurveillanceenvironmental occurrencehuman medicinerisk rankingpharmacokinetic featuresPortugalveterinary medicineAntibiotics represent a pharmacotherapeutic group widely used in both human and veterinary medicine for which ecosurveillance has been continually recommended. It is urgent to rank the antibiotics and highlight those that may pose potential risk to the environment, a key step for the risk management. The absence of this type of contributions applied to the Portuguese reality supported the idea of compiling the data presented herein. With such purpose the most recent and representative data is used to draw a comparative contribution of each antimicrobial classes according to their intended use, i.e., in human versus veterinary medicine. The aim was to assess: (1) the amount and patterns of antimicrobials usage between human and animals; (2) the qualitative comparison between the antimicrobial classes used in each practice (human and veterinary) or specific use; (3) the potential to enter the environment, metabolism, mode of action and environmental occurrences. This manuscript will, thus, identify priorities for the environmental risk assessment, considering the ranking of the antimicrobials by their usage and potential environmental exposure. Ultimately, this study will serve as a basis for future monitoring programs, guiding the policy of regulatory agencies.MDPI2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/109693http://hdl.handle.net/10316/109693https://doi.org/10.3390/toxics2020188eng2305-6304Almeida, AnabelaDuarte, SofiaNunes, RicardoRocha, HumbertoPena, AngelinaMeisel, Leonorinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-23T08:12:59Zoai:estudogeral.uc.pt:10316/109693Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:25:50.884739Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
title |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
spellingShingle |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance Almeida, Anabela antibiotics consumption ecosurveillance environmental occurrence human medicine risk ranking pharmacokinetic features Portugal veterinary medicine |
title_short |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
title_full |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
title_fullStr |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
title_full_unstemmed |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
title_sort |
Human and Veterinary Antibiotics Used in Portugal—A Ranking for Ecosurveillance |
author |
Almeida, Anabela |
author_facet |
Almeida, Anabela Duarte, Sofia Nunes, Ricardo Rocha, Humberto Pena, Angelina Meisel, Leonor |
author_role |
author |
author2 |
Duarte, Sofia Nunes, Ricardo Rocha, Humberto Pena, Angelina Meisel, Leonor |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Almeida, Anabela Duarte, Sofia Nunes, Ricardo Rocha, Humberto Pena, Angelina Meisel, Leonor |
dc.subject.por.fl_str_mv |
antibiotics consumption ecosurveillance environmental occurrence human medicine risk ranking pharmacokinetic features Portugal veterinary medicine |
topic |
antibiotics consumption ecosurveillance environmental occurrence human medicine risk ranking pharmacokinetic features Portugal veterinary medicine |
description |
Antibiotics represent a pharmacotherapeutic group widely used in both human and veterinary medicine for which ecosurveillance has been continually recommended. It is urgent to rank the antibiotics and highlight those that may pose potential risk to the environment, a key step for the risk management. The absence of this type of contributions applied to the Portuguese reality supported the idea of compiling the data presented herein. With such purpose the most recent and representative data is used to draw a comparative contribution of each antimicrobial classes according to their intended use, i.e., in human versus veterinary medicine. The aim was to assess: (1) the amount and patterns of antimicrobials usage between human and animals; (2) the qualitative comparison between the antimicrobial classes used in each practice (human and veterinary) or specific use; (3) the potential to enter the environment, metabolism, mode of action and environmental occurrences. This manuscript will, thus, identify priorities for the environmental risk assessment, considering the ranking of the antimicrobials by their usage and potential environmental exposure. Ultimately, this study will serve as a basis for future monitoring programs, guiding the policy of regulatory agencies. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/109693 http://hdl.handle.net/10316/109693 https://doi.org/10.3390/toxics2020188 |
url |
http://hdl.handle.net/10316/109693 https://doi.org/10.3390/toxics2020188 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2305-6304 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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