Genetic and environmental factors involved in the development of periodontal disease
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10284/7688 |
Resumo: | The goal of this work was to make a search on the genetic and environmental factors involved in the development of periodontal disease, in order to have a better understanding and therefore be able to give a better treatment to our patients. One of the most common immune/inflammatory disease of infectious origin is the periodontitis. This disease can have a negative impact in health and life quality, since patients can lose their teeth. Chronic and aggressive periodontal diseases are complex diseases with multifactorial etiology, that result in the destruction of the supporting structures of teeth. The immune system of the host plays an important role in this process. As environmental risk factors are smoking habits, nutrients and food diet, obesity and involved metabolic syndromes, stress and depression. Concerning genetic risk factors, several studies show the existence of familial aggregation and polymorphisms of diverse genes as well as epigenetic changes have been associated with increased susceptibility to periodontitis. |
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Genetic and environmental factors involved in the development of periodontal diseaseDomínio/Área Científica::Ciências Médicas::Medicina ClínicaThe goal of this work was to make a search on the genetic and environmental factors involved in the development of periodontal disease, in order to have a better understanding and therefore be able to give a better treatment to our patients. One of the most common immune/inflammatory disease of infectious origin is the periodontitis. This disease can have a negative impact in health and life quality, since patients can lose their teeth. Chronic and aggressive periodontal diseases are complex diseases with multifactorial etiology, that result in the destruction of the supporting structures of teeth. The immune system of the host plays an important role in this process. As environmental risk factors are smoking habits, nutrients and food diet, obesity and involved metabolic syndromes, stress and depression. Concerning genetic risk factors, several studies show the existence of familial aggregation and polymorphisms of diverse genes as well as epigenetic changes have been associated with increased susceptibility to periodontitis.O objetivo deste trabalho foi fazer uma pesquisa bibliográfica sobre os fatores genéticos e ambientais envolvidos no desenvolvimento da doença periodontal, de modo a uma melhor compreensão e, portanto, poder dar um melhor tratamento aos pacientes. A periodontite é uma das doenças imuno/inflamatórias mais comuns com origem infeciosa. Esta doença pode ter um impacto negativo na saúde e qualidade de vida, uma vez que os pacientes podem perder os dentes. Doenças periodontais crónica e agressiva são doenças complexas com etiologia multifatorial, que leva à destruição das estruturas de suporte dos dentes. O sistema imune do hospedeiro desempenha um papel importante neste processo. Como fatores ambientais estão os hábitos tabágicos, nutrientes e dieta alimentar, obesidade e síndromes metabólicos relacionados, stress e depressão. No que diz respeito a fatores de risco genéticos, vários estudos demonstram a existência de agregação familiar e polimorfismos de vários genes assim como alterações epigenéticas têm disso associados com aumento da suscetibilidade para periodontite.Cardoso, Inês LopesRepositório Institucional da Universidade Fernando PessoaNieto Medina, Daniela2019-06-27T15:28:25Z2019-04-232019-04-23T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10284/7688TID:202719294enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-13T02:01:33Zoai:bdigital.ufp.pt:10284/7688Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:44:35.838617Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Genetic and environmental factors involved in the development of periodontal disease |
title |
Genetic and environmental factors involved in the development of periodontal disease |
spellingShingle |
Genetic and environmental factors involved in the development of periodontal disease Nieto Medina, Daniela Domínio/Área Científica::Ciências Médicas::Medicina Clínica |
title_short |
Genetic and environmental factors involved in the development of periodontal disease |
title_full |
Genetic and environmental factors involved in the development of periodontal disease |
title_fullStr |
Genetic and environmental factors involved in the development of periodontal disease |
title_full_unstemmed |
Genetic and environmental factors involved in the development of periodontal disease |
title_sort |
Genetic and environmental factors involved in the development of periodontal disease |
author |
Nieto Medina, Daniela |
author_facet |
Nieto Medina, Daniela |
author_role |
author |
dc.contributor.none.fl_str_mv |
Cardoso, Inês Lopes Repositório Institucional da Universidade Fernando Pessoa |
dc.contributor.author.fl_str_mv |
Nieto Medina, Daniela |
dc.subject.por.fl_str_mv |
Domínio/Área Científica::Ciências Médicas::Medicina Clínica |
topic |
Domínio/Área Científica::Ciências Médicas::Medicina Clínica |
description |
The goal of this work was to make a search on the genetic and environmental factors involved in the development of periodontal disease, in order to have a better understanding and therefore be able to give a better treatment to our patients. One of the most common immune/inflammatory disease of infectious origin is the periodontitis. This disease can have a negative impact in health and life quality, since patients can lose their teeth. Chronic and aggressive periodontal diseases are complex diseases with multifactorial etiology, that result in the destruction of the supporting structures of teeth. The immune system of the host plays an important role in this process. As environmental risk factors are smoking habits, nutrients and food diet, obesity and involved metabolic syndromes, stress and depression. Concerning genetic risk factors, several studies show the existence of familial aggregation and polymorphisms of diverse genes as well as epigenetic changes have been associated with increased susceptibility to periodontitis. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-06-27T15:28:25Z 2019-04-23 2019-04-23T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10284/7688 TID:202719294 |
url |
http://hdl.handle.net/10284/7688 |
identifier_str_mv |
TID:202719294 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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