Multimorbidity profile of COVID-19 deaths in Portugal during 2020

Detalhes bibliográficos
Autor(a) principal: Nogueira, Paulo Jorge
Data de Publicação: 2022
Outros Autores: Nobre, Miguel de Araújo, Elias, Cecília, Feteira-Santos, Rodrigo, Martinho, António C.-V., Camarinha, Catarina, Bacelar-Nicolau, Leonor, Costa, Andreia, Furtado, Cristina, Morais, Liliane, Rachadell, Juan, Pinto, Mário Pereira, Pinto, Fausto J., Carneiro, António Vaz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/52339
Resumo: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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spelling Multimorbidity profile of COVID-19 deaths in Portugal during 2020COVID-19Charlson comorbidity indexElixhauser comorbidity indexPortugalComorbidityMortality© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Background: COVID-19 is caused by SARS-CoV-2 infection and has reached pandemic proportions. Since then, several clinical characteristics have been associated with poor outcomes. This study aimed to describe the morbidity profile of COVID-19 deaths in Portugal. Methods: A study was performed including deaths certificated in Portugal with "COVID-19" (ICD-10: U07.1 or U07.2) coded as the underlying cause of death from the National e-Death Certificates Information System between 16 March and 31 December 2020. Comorbidities were derived from ICD-10 codes using the Charlson and Elixhauser indexes. The resident Portuguese population estimates for 2020 were used. Results: The study included 6701 deaths (death rate: 65.1 deaths/100,000 inhabitants), predominantly males (72.1). The male-to-female mortality ratio was 1.1. The male-to-female mortality rate ratio was 1.2; however, within age groups, it varied 5.0-11.4-fold. COVID-19 deaths in Portugal during 2020 occurred mainly in individuals aged 80 years or older, predominantly in public healthcare institutions. Uncomplicated hypertension, uncomplicated diabetes mellitus, congestive heart failure, renal failure, cardiac arrhythmias, dementia, and cerebrovascular disease were observed among COVID-19 deceased patients, with prevalences higher than 10%. A high prevalence of zero morbidities was registered using both the Elixhauser and Charlson comorbidities lists (above 40.2%). Nevertheless, high multimorbidity was also identified at the time of COVID-19 death (about 36.5%). Higher multimorbidity levels were observed in men, increasing with age up to 80 years old. Zero-morbidity prevalence and high multimorbidity prevalences varied throughout the year 2020, seemingly more elevated in the mortality waves' peaks, suggesting variation according to the degree of disease incidence at a given period. Conclusions: This study provides detailed sociodemographic and clinical information on all certificated deaths from COVID-19 in Portugal during 2020, showing complex and extreme levels of morbidity (zero-morbidity vs. high multimorbidity) dynamics during the first year of the pandemic in Portugal.This publication was supported by Fundação para a Ciência e Tecnologia (FCT) under the references UIDB/04295/2020 and UIDP/04295/2020.MDPIRepositório da Universidade de LisboaNogueira, Paulo JorgeNobre, Miguel de AraújoElias, CecíliaFeteira-Santos, RodrigoMartinho, António C.-V.Camarinha, CatarinaBacelar-Nicolau, LeonorCosta, AndreiaFurtado, CristinaMorais, LilianeRachadell, JuanPinto, Mário PereiraPinto, Fausto J.Carneiro, António Vaz2022-04-13T15:47:22Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/52339engJ Clin Med. 2022 Mar 29;11(7):189810.3390/jcm110718982077-0383info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:57:29Zoai:repositorio.ul.pt:10451/52339Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:03:27.643020Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multimorbidity profile of COVID-19 deaths in Portugal during 2020
title Multimorbidity profile of COVID-19 deaths in Portugal during 2020
spellingShingle Multimorbidity profile of COVID-19 deaths in Portugal during 2020
Nogueira, Paulo Jorge
COVID-19
Charlson comorbidity index
Elixhauser comorbidity index
Portugal
Comorbidity
Mortality
title_short Multimorbidity profile of COVID-19 deaths in Portugal during 2020
title_full Multimorbidity profile of COVID-19 deaths in Portugal during 2020
title_fullStr Multimorbidity profile of COVID-19 deaths in Portugal during 2020
title_full_unstemmed Multimorbidity profile of COVID-19 deaths in Portugal during 2020
title_sort Multimorbidity profile of COVID-19 deaths in Portugal during 2020
author Nogueira, Paulo Jorge
author_facet Nogueira, Paulo Jorge
Nobre, Miguel de Araújo
Elias, Cecília
Feteira-Santos, Rodrigo
Martinho, António C.-V.
Camarinha, Catarina
Bacelar-Nicolau, Leonor
Costa, Andreia
Furtado, Cristina
Morais, Liliane
Rachadell, Juan
Pinto, Mário Pereira
Pinto, Fausto J.
Carneiro, António Vaz
author_role author
author2 Nobre, Miguel de Araújo
Elias, Cecília
Feteira-Santos, Rodrigo
Martinho, António C.-V.
Camarinha, Catarina
Bacelar-Nicolau, Leonor
Costa, Andreia
Furtado, Cristina
Morais, Liliane
Rachadell, Juan
Pinto, Mário Pereira
Pinto, Fausto J.
Carneiro, António Vaz
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Nogueira, Paulo Jorge
Nobre, Miguel de Araújo
Elias, Cecília
Feteira-Santos, Rodrigo
Martinho, António C.-V.
Camarinha, Catarina
Bacelar-Nicolau, Leonor
Costa, Andreia
Furtado, Cristina
Morais, Liliane
Rachadell, Juan
Pinto, Mário Pereira
Pinto, Fausto J.
Carneiro, António Vaz
dc.subject.por.fl_str_mv COVID-19
Charlson comorbidity index
Elixhauser comorbidity index
Portugal
Comorbidity
Mortality
topic COVID-19
Charlson comorbidity index
Elixhauser comorbidity index
Portugal
Comorbidity
Mortality
description © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2022
dc.date.none.fl_str_mv 2022-04-13T15:47:22Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/52339
url http://hdl.handle.net/10451/52339
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Clin Med. 2022 Mar 29;11(7):1898
10.3390/jcm11071898
2077-0383
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eu_rights_str_mv openAccess
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