The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding

Detalhes bibliográficos
Autor(a) principal: Nunes, Gonçalo Pedro da Silva
Data de Publicação: 2018
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/130062
Resumo: Dissertation presented to obtain the Master degree in Biochemistry for Health
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spelling The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA bindingKaposi’s sarcoma herpesvirusLatency associated nuclear antigenUbiquitin Specific Protease 7LANA-USP7 complexLana Binding Site DNADissertation presented to obtain the Master degree in Biochemistry for HealthThe implications of USP7 (Ubiquitin Specific Protease 7, deubiquitinating enzyme involved in several crucial molecular pathways) interactions with LANA (Latency Associated Nuclear Antigen protein, that facilitates the tethering of viral γ-Herpesvirus episomes into the host’s DNA and promotes its replication) has multiple health consequences, since USP7 is a protein that has an essential role it the regulation of many cellular functions, like the p53-mdm2 pathway, that regulates cellular apoptosis and prevents cancer.Universidade Nova de Lisboa. Instituto de Tecnologia Quimica e Biológica António XavierRUNNunes, Gonçalo Pedro da Silva2022-01-01T21:19:48Z2018-092018-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/130062enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:08:52Zoai:run.unl.pt:10362/130062Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:46:41.219919Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
title The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
spellingShingle The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
Nunes, Gonçalo Pedro da Silva
Kaposi’s sarcoma herpesvirus
Latency associated nuclear antigen
Ubiquitin Specific Protease 7
LANA-USP7 complex
Lana Binding Site DNA
title_short The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
title_full The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
title_fullStr The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
title_full_unstemmed The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
title_sort The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA binding
author Nunes, Gonçalo Pedro da Silva
author_facet Nunes, Gonçalo Pedro da Silva
author_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Nunes, Gonçalo Pedro da Silva
dc.subject.por.fl_str_mv Kaposi’s sarcoma herpesvirus
Latency associated nuclear antigen
Ubiquitin Specific Protease 7
LANA-USP7 complex
Lana Binding Site DNA
topic Kaposi’s sarcoma herpesvirus
Latency associated nuclear antigen
Ubiquitin Specific Protease 7
LANA-USP7 complex
Lana Binding Site DNA
description Dissertation presented to obtain the Master degree in Biochemistry for Health
publishDate 2018
dc.date.none.fl_str_mv 2018-09
2018-09-01T00:00:00Z
2022-01-01T21:19:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/130062
url http://hdl.handle.net/10362/130062
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Quimica e Biológica António Xavier
publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Quimica e Biológica António Xavier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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