Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms

Detalhes bibliográficos
Autor(a) principal: Policarpo, Sara
Data de Publicação: 2019
Outros Autores: Rodrigues, Teresa, Moreira, Ana Catarina, Valadas, Emília
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/44931
Resumo: © 2019 Published by Elsevier España, S.L.U. on behalf of Sociedade Portuguesa de Cardiologia. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)
id RCAP_f5b0077046196bccc1132068615eb58e
oai_identifier_str oai:repositorio.ul.pt:10451/44931
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithmsRisco cardiovascular em infetados por VIH : comparação de três ferramentas de avaliaçãoCardiovascular riskHIV/Acquired immunodeficiency syndromeMetabolic syndromePortugal© 2019 Published by Elsevier España, S.L.U. on behalf of Sociedade Portuguesa de Cardiologia. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)Introduction: Cardiovascular (CV) risk is known to be increased in HIV-infected individuals. Our aim was to assess CV risk in HIV-infected adults. Methods: CV risk was estimated for each patient using three different risk algorithms: SCORE, the Framingham risk score (FRS), and DAD. Patients were classified as at low, moderate or high CV risk. Clinical and anthropometric data were collected. Results: We included 571 HIV-infected individuals, mostly male (67.1%; n=383). Patients were divided into two groups according to antiretroviral therapy (ART): naïve (7.5%; n=43) or under ART (92.5%; n=528). The mean time since HIV diagnosis was 6.7±6.5 years in the naive group and 13.3±6.1 years in the ART group. Metabolic syndrome (MS) was identified in 33.9% (n=179) and 16.3% (n=7) of participants in the ART and naïve groups, respectively. MS was associated with ART (OR=2.7; p=0.018). Triglycerides ≥150 mg/dl (OR=13.643, p<0.001) was one of the major factors contributing to MS. Overall, high CV risk was found in 4.4% (n=23) of patients when the SCORE tool was used, in 20.5% (n=117) using the FRS, and in 10.3% (n=59) using the DAD score. The observed agreement between the FRS and SCORE was 55.4% (k=0.183, p<0.001), between the FRS and DAD 70.5% (k=0.465, p<0.001), and between SCORE and DAD 72.3% (k=0.347, p<0.001). Conclusion: On the basis of the three algorithms, we detected a high rate of high CV risk, particularly in patients under ART. The FRS was the algorithm that classified most patients in the high CV risk category (20.5%). In addition, a high prevalence of MS was identified in this patient group.ElsevierRepositório da Universidade de LisboaPolicarpo, SaraRodrigues, TeresaMoreira, Ana CatarinaValadas, Emília2020-11-19T11:26:21Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/44931engRev Port Cardiol. 2019 Jul;38(7):463-4700870-255110.1016/j.repc.2019.08.0022174-2030info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:46:18Zoai:repositorio.ul.pt:10451/44931Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:57:25.469196Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
Risco cardiovascular em infetados por VIH : comparação de três ferramentas de avaliação
title Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
spellingShingle Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
Policarpo, Sara
Cardiovascular risk
HIV/Acquired immunodeficiency syndrome
Metabolic syndrome
Portugal
title_short Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
title_full Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
title_fullStr Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
title_full_unstemmed Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
title_sort Cardiovascular risk in HIV-infected individuals : a comparison of three risk prediction algorithms
author Policarpo, Sara
author_facet Policarpo, Sara
Rodrigues, Teresa
Moreira, Ana Catarina
Valadas, Emília
author_role author
author2 Rodrigues, Teresa
Moreira, Ana Catarina
Valadas, Emília
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Policarpo, Sara
Rodrigues, Teresa
Moreira, Ana Catarina
Valadas, Emília
dc.subject.por.fl_str_mv Cardiovascular risk
HIV/Acquired immunodeficiency syndrome
Metabolic syndrome
Portugal
topic Cardiovascular risk
HIV/Acquired immunodeficiency syndrome
Metabolic syndrome
Portugal
description © 2019 Published by Elsevier España, S.L.U. on behalf of Sociedade Portuguesa de Cardiologia. This is an open access article under CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2020-11-19T11:26:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/44931
url http://hdl.handle.net/10451/44931
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Port Cardiol. 2019 Jul;38(7):463-470
0870-2551
10.1016/j.repc.2019.08.002
2174-2030
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799134517221392384

Registros relacionados