Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/136116 |
Resumo: | Funding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s). |
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Impact of the COVID-19 Pandemic on Breast Cancer Management in PortugalA Cross-Sectional Survey-Based Study of Medical OncologistsBreast cancerClinical practiceCOVID-19Patient managementOncologySDG 3 - Good Health and Well-beingFunding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s).Introduction: Cancer care providers have faced many challenges in delivering safe care for patients during the COVID-19 pandemic. This cross-sectional survey-based study investigated the impact of the pandemic on clinical practices of Portuguese medical oncologists caring for patients with breast cancer. Methods: An anonymous online survey comprising 42 questions gathered information regarding COVID-19 testing, treatment in (neo)adjuvant and metastatic settings, and other aspects of breast cancer management. Practices before and during the pandemic were compared, and potential differences in outcomes according to respondents’ regions, case volumes, and practice type were explored. Results: Of 129 respondents, 108 worked in the public health system, giving a representative national picture of the impact of the COVID-19 pandemic on breast cancer management. Seventy-one percent of respondents reported a reduction in visits for new cases of breast cancer, and there was a shift towards increased use of telemedicine. Clinical decision-making was largely unaffected in the most aggressive indications (i.e., triple-negative, HER2-positive, visceral crisis). The use of neoadjuvant therapy increased when access to surgery was difficult, whereas dose-dense regimens decreased, and cyclin-dependent kinase 4/6 inhibitor treatment decreased for less aggressive disease and increased for more aggressive disease. The use of oral formulations and metronomic chemotherapy regimens increased, and clinical trial participation decreased. Some differences by respondents’ region and case volume were noted. Conclusion: Medical oncologists in Portugal implemented many changes during the COVID-19 pandemic, most of which were logical and reasonable responses to the current healthcare emergency; however, the true impact on patient outcomes remains unknown.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNAlpuim Costa, DiogoNobre, José Guilherme GonçalvesFernandes, João PauloBatista, Marta VazSimas, AnaSales, CarolinaGouveia, HelenaRibeiro, Leonor AbreuCoelho, AndreiaBrito, MargaridaInácio, MarianaCruz, AndréMariano, MónicaSavva-Bordalo, JoanaFernandes, RicardoOliveira, AndréChaves, AndreiaFontes-Sousa, MárioSampaio-Alves, MafaldaMartins-Branco, DiogoAfonso, Noémia2022-04-08T22:35:44Z2022-03-212022-03-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/136116eng2366-1070PURE: 42882377https://doi.org/10.1007/s40487-022-00191-7info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:01:02Zoai:run.unl.pt:10362/136116Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:01:02Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal A Cross-Sectional Survey-Based Study of Medical Oncologists |
title |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
spellingShingle |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal Alpuim Costa, Diogo Breast cancer Clinical practice COVID-19 Patient management Oncology SDG 3 - Good Health and Well-being |
title_short |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
title_full |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
title_fullStr |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
title_full_unstemmed |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
title_sort |
Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal |
author |
Alpuim Costa, Diogo |
author_facet |
Alpuim Costa, Diogo Nobre, José Guilherme Gonçalves Fernandes, João Paulo Batista, Marta Vaz Simas, Ana Sales, Carolina Gouveia, Helena Ribeiro, Leonor Abreu Coelho, Andreia Brito, Margarida Inácio, Mariana Cruz, André Mariano, Mónica Savva-Bordalo, Joana Fernandes, Ricardo Oliveira, André Chaves, Andreia Fontes-Sousa, Mário Sampaio-Alves, Mafalda Martins-Branco, Diogo Afonso, Noémia |
author_role |
author |
author2 |
Nobre, José Guilherme Gonçalves Fernandes, João Paulo Batista, Marta Vaz Simas, Ana Sales, Carolina Gouveia, Helena Ribeiro, Leonor Abreu Coelho, Andreia Brito, Margarida Inácio, Mariana Cruz, André Mariano, Mónica Savva-Bordalo, Joana Fernandes, Ricardo Oliveira, André Chaves, Andreia Fontes-Sousa, Mário Sampaio-Alves, Mafalda Martins-Branco, Diogo Afonso, Noémia |
author2_role |
author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Alpuim Costa, Diogo Nobre, José Guilherme Gonçalves Fernandes, João Paulo Batista, Marta Vaz Simas, Ana Sales, Carolina Gouveia, Helena Ribeiro, Leonor Abreu Coelho, Andreia Brito, Margarida Inácio, Mariana Cruz, André Mariano, Mónica Savva-Bordalo, Joana Fernandes, Ricardo Oliveira, André Chaves, Andreia Fontes-Sousa, Mário Sampaio-Alves, Mafalda Martins-Branco, Diogo Afonso, Noémia |
dc.subject.por.fl_str_mv |
Breast cancer Clinical practice COVID-19 Patient management Oncology SDG 3 - Good Health and Well-being |
topic |
Breast cancer Clinical practice COVID-19 Patient management Oncology SDG 3 - Good Health and Well-being |
description |
Funding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s). |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-08T22:35:44Z 2022-03-21 2022-03-21T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
status_str |
publishedVersion |
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http://hdl.handle.net/10362/136116 |
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eng |
language |
eng |
dc.relation.none.fl_str_mv |
2366-1070 PURE: 42882377 https://doi.org/10.1007/s40487-022-00191-7 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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