Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal

Detalhes bibliográficos
Autor(a) principal: Alpuim Costa, Diogo
Data de Publicação: 2022
Outros Autores: Nobre, José Guilherme Gonçalves, Fernandes, João Paulo, Batista, Marta Vaz, Simas, Ana, Sales, Carolina, Gouveia, Helena, Ribeiro, Leonor Abreu, Coelho, Andreia, Brito, Margarida, Inácio, Mariana, Cruz, André, Mariano, Mónica, Savva-Bordalo, Joana, Fernandes, Ricardo, Oliveira, André, Chaves, Andreia, Fontes-Sousa, Mário, Sampaio-Alves, Mafalda, Martins-Branco, Diogo, Afonso, Noémia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/136116
Resumo: Funding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s).
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spelling Impact of the COVID-19 Pandemic on Breast Cancer Management in PortugalA Cross-Sectional Survey-Based Study of Medical OncologistsBreast cancerClinical practiceCOVID-19Patient managementOncologySDG 3 - Good Health and Well-beingFunding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s).Introduction: Cancer care providers have faced many challenges in delivering safe care for patients during the COVID-19 pandemic. This cross-sectional survey-based study investigated the impact of the pandemic on clinical practices of Portuguese medical oncologists caring for patients with breast cancer. Methods: An anonymous online survey comprising 42 questions gathered information regarding COVID-19 testing, treatment in (neo)adjuvant and metastatic settings, and other aspects of breast cancer management. Practices before and during the pandemic were compared, and potential differences in outcomes according to respondents’ regions, case volumes, and practice type were explored. Results: Of 129 respondents, 108 worked in the public health system, giving a representative national picture of the impact of the COVID-19 pandemic on breast cancer management. Seventy-one percent of respondents reported a reduction in visits for new cases of breast cancer, and there was a shift towards increased use of telemedicine. Clinical decision-making was largely unaffected in the most aggressive indications (i.e., triple-negative, HER2-positive, visceral crisis). The use of neoadjuvant therapy increased when access to surgery was difficult, whereas dose-dense regimens decreased, and cyclin-dependent kinase 4/6 inhibitor treatment decreased for less aggressive disease and increased for more aggressive disease. The use of oral formulations and metronomic chemotherapy regimens increased, and clinical trial participation decreased. Some differences by respondents’ region and case volume were noted. Conclusion: Medical oncologists in Portugal implemented many changes during the COVID-19 pandemic, most of which were logical and reasonable responses to the current healthcare emergency; however, the true impact on patient outcomes remains unknown.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNAlpuim Costa, DiogoNobre, José Guilherme GonçalvesFernandes, João PauloBatista, Marta VazSimas, AnaSales, CarolinaGouveia, HelenaRibeiro, Leonor AbreuCoelho, AndreiaBrito, MargaridaInácio, MarianaCruz, AndréMariano, MónicaSavva-Bordalo, JoanaFernandes, RicardoOliveira, AndréChaves, AndreiaFontes-Sousa, MárioSampaio-Alves, MafaldaMartins-Branco, DiogoAfonso, Noémia2022-04-08T22:35:44Z2022-03-212022-03-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/136116eng2366-1070PURE: 42882377https://doi.org/10.1007/s40487-022-00191-7info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:22Zoai:run.unl.pt:10362/136116Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:37.957640Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
A Cross-Sectional Survey-Based Study of Medical Oncologists
title Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
spellingShingle Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
Alpuim Costa, Diogo
Breast cancer
Clinical practice
COVID-19
Patient management
Oncology
SDG 3 - Good Health and Well-being
title_short Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
title_full Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
title_fullStr Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
title_full_unstemmed Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
title_sort Impact of the COVID-19 Pandemic on Breast Cancer Management in Portugal
author Alpuim Costa, Diogo
author_facet Alpuim Costa, Diogo
Nobre, José Guilherme Gonçalves
Fernandes, João Paulo
Batista, Marta Vaz
Simas, Ana
Sales, Carolina
Gouveia, Helena
Ribeiro, Leonor Abreu
Coelho, Andreia
Brito, Margarida
Inácio, Mariana
Cruz, André
Mariano, Mónica
Savva-Bordalo, Joana
Fernandes, Ricardo
Oliveira, André
Chaves, Andreia
Fontes-Sousa, Mário
Sampaio-Alves, Mafalda
Martins-Branco, Diogo
Afonso, Noémia
author_role author
author2 Nobre, José Guilherme Gonçalves
Fernandes, João Paulo
Batista, Marta Vaz
Simas, Ana
Sales, Carolina
Gouveia, Helena
Ribeiro, Leonor Abreu
Coelho, Andreia
Brito, Margarida
Inácio, Mariana
Cruz, André
Mariano, Mónica
Savva-Bordalo, Joana
Fernandes, Ricardo
Oliveira, André
Chaves, Andreia
Fontes-Sousa, Mário
Sampaio-Alves, Mafalda
Martins-Branco, Diogo
Afonso, Noémia
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Alpuim Costa, Diogo
Nobre, José Guilherme Gonçalves
Fernandes, João Paulo
Batista, Marta Vaz
Simas, Ana
Sales, Carolina
Gouveia, Helena
Ribeiro, Leonor Abreu
Coelho, Andreia
Brito, Margarida
Inácio, Mariana
Cruz, André
Mariano, Mónica
Savva-Bordalo, Joana
Fernandes, Ricardo
Oliveira, André
Chaves, Andreia
Fontes-Sousa, Mário
Sampaio-Alves, Mafalda
Martins-Branco, Diogo
Afonso, Noémia
dc.subject.por.fl_str_mv Breast cancer
Clinical practice
COVID-19
Patient management
Oncology
SDG 3 - Good Health and Well-being
topic Breast cancer
Clinical practice
COVID-19
Patient management
Oncology
SDG 3 - Good Health and Well-being
description Funding Information: We would like to thank Andrea Bothwell who wrote the manuscript outline and first draft on behalf of Springer Healthcare Communications. We also thank Prof. Carina Silva (ESTEsL – Escola Superior de Tecnologias de Saúde de Lisboa) who performed the preliminary statistical analysis of this study. This medical writing assistance and statistical analysis was funded by CUF Oncologia. Funding Information: Diogo Alpuim Costa has received honoraria from the Portuguese Navy, CUF Oncologia, and NTT DATA, and has served as a speaker, advisory board member, or has received research or education funding from CUF Oncologia, AstraZeneca, Hoffmann-La Roche, Merck KGaA, Novartis, Pfizer, Uriage, Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Nanobiotix, Puma Biotechnology Inc., Sanofi, and Seagen Inc. Margarida Brito has participated as advisory board member for Roche, Novartis, Merck Sharp & Dohme, and Pfizer. Mário Fontes-Sousa has served as a speaker or advisory board member for Bristol Myers Squibb, Daiichi Sankyo, Gilead, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Servier. Diogo Martins-Branco received honoraria and advisory board fees from Janssen, Pfizer, Merck Sharp & Dohme, Angelini, AstraZeneca, and Novartis, meeting and travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, and Roche, and institutional grants from F. Hoffmann-La Roche Ltd. José Guilherme Gonçalves Nobre, João Paulo Fernandes, Marta Vaz Batista, Ana Simas, Carolina Sales, Helena Gouveia, Leonor Abreu Ribeiro, Andreia Coelho, Mariana Inácio, André Cruz, Mónica Mariano, Joana Savva-Bordalo, Ricardo Fernandes, André Oliveira, Andreia Chaves, Mafalda Sampaio-Alves, and Noémia Afonso have nothing to declare. Publisher Copyright: © 2022, The Author(s).
publishDate 2022
dc.date.none.fl_str_mv 2022-04-08T22:35:44Z
2022-03-21
2022-03-21T00:00:00Z
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dc.language.iso.fl_str_mv eng
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PURE: 42882377
https://doi.org/10.1007/s40487-022-00191-7
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