Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/23355 |
Resumo: | Historical specimens in museum collections provide opportunities to gain insights into the genomic past. For the Western honey bee, Apis mellifera L., this is particularly important because its populations are currently under threat worldwide and have experienced many changes in management and environment over the last century. Using Swiss Apis mellifera mellifera as a case study, our research provides important insights into the genetic diversity of native honey bees prior to the industrial-scale introductions and trade of non-native stocks during the 20th century-the onset of intensive commercial breeding and the decline of wild honey bees following the arrival of Varroa destructor. We sequenced whole-genomes of 22 honey bees from the Natural History Museum in Bern collected in Switzerland, including the oldest A. mellifera sample ever sequenced. We identify both, a historic and a recent migrant, natural or human-mediated, which corroborates with the population history of honey bees in Switzerland. Contrary to what we expected, we find no evidence for a significant genetic bottleneck in Swiss honey bees, and find that genetic diversity is not only maintained, but even slightly increased, most probably due to modern apicultural practices. Finally, we identify signals of selection between historic and modern honey bee populations associated with genes enriched in functions linked to xenobiotics, suggesting a possible selective pressure from the increasing use and diversity of chemicals used in agriculture and apiculture over the last century. |
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Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum SpecimensApis mellifera melliferaBiodiversityGenetic diversityHaplotype phasingMuseum GenomicsSelection signaturesHistorical specimens in museum collections provide opportunities to gain insights into the genomic past. For the Western honey bee, Apis mellifera L., this is particularly important because its populations are currently under threat worldwide and have experienced many changes in management and environment over the last century. Using Swiss Apis mellifera mellifera as a case study, our research provides important insights into the genetic diversity of native honey bees prior to the industrial-scale introductions and trade of non-native stocks during the 20th century-the onset of intensive commercial breeding and the decline of wild honey bees following the arrival of Varroa destructor. We sequenced whole-genomes of 22 honey bees from the Natural History Museum in Bern collected in Switzerland, including the oldest A. mellifera sample ever sequenced. We identify both, a historic and a recent migrant, natural or human-mediated, which corroborates with the population history of honey bees in Switzerland. Contrary to what we expected, we find no evidence for a significant genetic bottleneck in Swiss honey bees, and find that genetic diversity is not only maintained, but even slightly increased, most probably due to modern apicultural practices. Finally, we identify signals of selection between historic and modern honey bee populations associated with genes enriched in functions linked to xenobiotics, suggesting a possible selective pressure from the increasing use and diversity of chemicals used in agriculture and apiculture over the last century.Biblioteca Digital do IPBParejo, MelanieWragg, DavidHenriques, DoraCharrière, Jean DanielEstonba, Andone2018-01-19T10:00:00Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/23355engParejo, Melanie; Wragg, David; Henriques, Dora; Charrière, Jean Daniel; Estonba, Andone (2020). Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens. Genome Biology and Evolution. ISSN 1759-6653. 12:12, p. 2535-255110.1093/gbe/evaa188info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:52:31Zoai:bibliotecadigital.ipb.pt:10198/23355Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:14:30.125945Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
title |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
spellingShingle |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens Parejo, Melanie Apis mellifera mellifera Biodiversity Genetic diversity Haplotype phasing Museum Genomics Selection signatures |
title_short |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
title_full |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
title_fullStr |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
title_full_unstemmed |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
title_sort |
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens |
author |
Parejo, Melanie |
author_facet |
Parejo, Melanie Wragg, David Henriques, Dora Charrière, Jean Daniel Estonba, Andone |
author_role |
author |
author2 |
Wragg, David Henriques, Dora Charrière, Jean Daniel Estonba, Andone |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Parejo, Melanie Wragg, David Henriques, Dora Charrière, Jean Daniel Estonba, Andone |
dc.subject.por.fl_str_mv |
Apis mellifera mellifera Biodiversity Genetic diversity Haplotype phasing Museum Genomics Selection signatures |
topic |
Apis mellifera mellifera Biodiversity Genetic diversity Haplotype phasing Museum Genomics Selection signatures |
description |
Historical specimens in museum collections provide opportunities to gain insights into the genomic past. For the Western honey bee, Apis mellifera L., this is particularly important because its populations are currently under threat worldwide and have experienced many changes in management and environment over the last century. Using Swiss Apis mellifera mellifera as a case study, our research provides important insights into the genetic diversity of native honey bees prior to the industrial-scale introductions and trade of non-native stocks during the 20th century-the onset of intensive commercial breeding and the decline of wild honey bees following the arrival of Varroa destructor. We sequenced whole-genomes of 22 honey bees from the Natural History Museum in Bern collected in Switzerland, including the oldest A. mellifera sample ever sequenced. We identify both, a historic and a recent migrant, natural or human-mediated, which corroborates with the population history of honey bees in Switzerland. Contrary to what we expected, we find no evidence for a significant genetic bottleneck in Swiss honey bees, and find that genetic diversity is not only maintained, but even slightly increased, most probably due to modern apicultural practices. Finally, we identify signals of selection between historic and modern honey bee populations associated with genes enriched in functions linked to xenobiotics, suggesting a possible selective pressure from the increasing use and diversity of chemicals used in agriculture and apiculture over the last century. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/23355 |
url |
http://hdl.handle.net/10198/23355 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Parejo, Melanie; Wragg, David; Henriques, Dora; Charrière, Jean Daniel; Estonba, Andone (2020). Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens. Genome Biology and Evolution. ISSN 1759-6653. 12:12, p. 2535-2551 10.1093/gbe/evaa188 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799135424401113088 |