The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838 |
Resumo: | Introduction: Infections are a major problem and the presence of drug-resistant microorganisms has significant clinical and economic impact. The present study aims to evaluate the epidemiological profile of “problem” microorganisms isolated in a hospital in the north of Portugal.Material and Methods: All isolated microorganisms were analyzed, between January 2014 and June 2015. Data obtained was then processed using statistical software.Results: We analyzed 8146 microbiological isolations and found a prevalence of 23% of ‘problem’ microorganisms (in descending order of frequency: Enterococcus, Pseudomonas, Staphylococcus aureus e Streptococcus pneumonia), 57.55% of which isolated in male patients. The most frequent mechanism of drug resistance for the overall sample was the production of extended-spectrum beta-lactamase, and resistance to oxacillin for ‘problem’ microorganisms.Discussion: In this sample, we observed a much higher prevalence of ‘problem’ microorganisms than that reported in other countries, which shows the need of improvement of surveillance mechanisms and treatment of these cases. Microorganisms that showed higher resistance were Staphylococcus aureus (resistant to oxacillin) and Enterococcus (resistant to vancomycin). Those were isolated in patients with a higher mean age compared to non-resistant microorganisms. Most of these microorganisms were isolated in hospitalized patients or intermediate and intensive care units, what relates them with healthcare associated infections.Conclusion: The prevalence of infection by ‘problem’ microorganisms during the studied period was 23%. The detection and control of the spread of these microorganisms are paramount due to its impact on health costs, morbidity and survival of patients. |
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The Epidemiological Profile of the Isolation of ‘Problem’ MicroorganismsPerfil Epidemiológico dos Isolamentos dos Microrganismos ‘Problema’Drug ResistanceMicrobialInfection/epidemiologyPortugalInfecção/epidemiologiaPortugalResistência Microbiana a MedicamentosIntroduction: Infections are a major problem and the presence of drug-resistant microorganisms has significant clinical and economic impact. The present study aims to evaluate the epidemiological profile of “problem” microorganisms isolated in a hospital in the north of Portugal.Material and Methods: All isolated microorganisms were analyzed, between January 2014 and June 2015. Data obtained was then processed using statistical software.Results: We analyzed 8146 microbiological isolations and found a prevalence of 23% of ‘problem’ microorganisms (in descending order of frequency: Enterococcus, Pseudomonas, Staphylococcus aureus e Streptococcus pneumonia), 57.55% of which isolated in male patients. The most frequent mechanism of drug resistance for the overall sample was the production of extended-spectrum beta-lactamase, and resistance to oxacillin for ‘problem’ microorganisms.Discussion: In this sample, we observed a much higher prevalence of ‘problem’ microorganisms than that reported in other countries, which shows the need of improvement of surveillance mechanisms and treatment of these cases. Microorganisms that showed higher resistance were Staphylococcus aureus (resistant to oxacillin) and Enterococcus (resistant to vancomycin). Those were isolated in patients with a higher mean age compared to non-resistant microorganisms. Most of these microorganisms were isolated in hospitalized patients or intermediate and intensive care units, what relates them with healthcare associated infections.Conclusion: The prevalence of infection by ‘problem’ microorganisms during the studied period was 23%. The detection and control of the spread of these microorganisms are paramount due to its impact on health costs, morbidity and survival of patients.Introdução: As infeções são um problema cada vez mais frequente e a presença de microrganismos resistentes cria impacto clínico e económico. Este estudo tem por objetivo determinar o perfil epidemiológico dos microrganismos ‘problema’ isolados num hospital do norte de Portugal.Material e Métodos: Foram analisados todos os isolamentos microbiológicos, entre janeiro de 2014 a junho de 2015. Os dados foram tratados em software estatístico.Resultados: Analisaram-se 8146 isolamentos microbiológicos, nos quais se obtiveram 23% de isolamentos de microrganismos ‘problema’ (por ordem decrescente de frequência: Enterococcus, Pseudomonas, Staphylococcus aureus e Streptococcus pneumonia), sendo 57,55% em doentes do sexo masculino. O mecanismo de resistência mais frequente foi a produção de betalactamase de espectro estendido no global dos isolamentos e a resistência à oxacilina nos microrganismos ‘problema’.Discussão: Nesta amostra, observou-se uma incidência bastante superior de microrganismos problema àquela publicada noutros países, o que remete para a necessidade da melhoria de mecanismos de vigilância e tratamento destes casos. Os microrganismos que apresentaram mais resistências foram o Staphylococcus aureus (resistente à oxacilina) e o Enterococcus (resistente à vancomicina), tendo-se verificado que a média de idades nestes casos era superior à dos não resistentes. A maioria destes microrganismos foi isolada no internamento e unidades de cuidados diferenciados, o que os relaciona a infeções associadas aos cuidados de saúde.Conclusão: A prevalência de infeção por microrganismos ‘problema’ no período estudado foi de 23%. É importante a deteção e o controle da disseminação destes microrganismos pelo seu impacto nos custos em saúde, morbilidade e sobrevida dos doentes.Ordem dos Médicos2019-09-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfimage/pngimage/pngimage/pngapplication/mswordapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838oai:ojs.www.actamedicaportuguesa.com:article/10838Acta Médica Portuguesa; Vol. 32 No. 9 (2019): September; 600-605Acta Médica Portuguesa; Vol. 32 N.º 9 (2019): Setembro; 600-6051646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/5757https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/5758https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10379https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10380https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10381https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10382https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10425https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/11360https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/11389Direitos de Autor (c) 2019 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessAtilano Carvalho, PedroMonteiro, AnaAlmeida, BrunoCorreia, Filomena HortaResende, VeraNunes, CarlaLopes, Sílvia2022-12-20T11:06:06Zoai:ojs.www.actamedicaportuguesa.com:article/10838Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:57.222284Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms Perfil Epidemiológico dos Isolamentos dos Microrganismos ‘Problema’ |
title |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
spellingShingle |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms Atilano Carvalho, Pedro Drug Resistance Microbial Infection/epidemiology Portugal Infecção/epidemiologia Portugal Resistência Microbiana a Medicamentos |
title_short |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
title_full |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
title_fullStr |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
title_full_unstemmed |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
title_sort |
The Epidemiological Profile of the Isolation of ‘Problem’ Microorganisms |
author |
Atilano Carvalho, Pedro |
author_facet |
Atilano Carvalho, Pedro Monteiro, Ana Almeida, Bruno Correia, Filomena Horta Resende, Vera Nunes, Carla Lopes, Sílvia |
author_role |
author |
author2 |
Monteiro, Ana Almeida, Bruno Correia, Filomena Horta Resende, Vera Nunes, Carla Lopes, Sílvia |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Atilano Carvalho, Pedro Monteiro, Ana Almeida, Bruno Correia, Filomena Horta Resende, Vera Nunes, Carla Lopes, Sílvia |
dc.subject.por.fl_str_mv |
Drug Resistance Microbial Infection/epidemiology Portugal Infecção/epidemiologia Portugal Resistência Microbiana a Medicamentos |
topic |
Drug Resistance Microbial Infection/epidemiology Portugal Infecção/epidemiologia Portugal Resistência Microbiana a Medicamentos |
description |
Introduction: Infections are a major problem and the presence of drug-resistant microorganisms has significant clinical and economic impact. The present study aims to evaluate the epidemiological profile of “problem” microorganisms isolated in a hospital in the north of Portugal.Material and Methods: All isolated microorganisms were analyzed, between January 2014 and June 2015. Data obtained was then processed using statistical software.Results: We analyzed 8146 microbiological isolations and found a prevalence of 23% of ‘problem’ microorganisms (in descending order of frequency: Enterococcus, Pseudomonas, Staphylococcus aureus e Streptococcus pneumonia), 57.55% of which isolated in male patients. The most frequent mechanism of drug resistance for the overall sample was the production of extended-spectrum beta-lactamase, and resistance to oxacillin for ‘problem’ microorganisms.Discussion: In this sample, we observed a much higher prevalence of ‘problem’ microorganisms than that reported in other countries, which shows the need of improvement of surveillance mechanisms and treatment of these cases. Microorganisms that showed higher resistance were Staphylococcus aureus (resistant to oxacillin) and Enterococcus (resistant to vancomycin). Those were isolated in patients with a higher mean age compared to non-resistant microorganisms. Most of these microorganisms were isolated in hospitalized patients or intermediate and intensive care units, what relates them with healthcare associated infections.Conclusion: The prevalence of infection by ‘problem’ microorganisms during the studied period was 23%. The detection and control of the spread of these microorganisms are paramount due to its impact on health costs, morbidity and survival of patients. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09-02 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838 oai:ojs.www.actamedicaportuguesa.com:article/10838 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838 |
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oai:ojs.www.actamedicaportuguesa.com:article/10838 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/5757 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/5758 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10379 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10380 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10381 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10382 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/10425 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/11360 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10838/11389 |
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Direitos de Autor (c) 2019 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2019 Acta Médica Portuguesa |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 32 No. 9 (2019): September; 600-605 Acta Médica Portuguesa; Vol. 32 N.º 9 (2019): Setembro; 600-605 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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