Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/12421 |
Resumo: | Three different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent. |
id |
RCAP_fa1214dd55ff4146265647f1c8c0b7c8 |
---|---|
oai_identifier_str |
oai:bibliotecadigital.ipb.pt:10198/12421 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis WelwCochlospermum angolensisInfusion/pills/syrupPhenolic compoundsAntimicrobial activityClinical isolatesThree different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.The authors are grateful to Foundation for Science and Technology (FCT, Portugal) for financial support to the research center CIMO (strategic project PEst-OE/AGR/UI0690/2014) and L. Barros researcher contract under “Programa Compromisso com Ciência – 2008”.ElsevierBiblioteca Digital do IPBPereira, CarlaBarros, LillianAlves, Maria JoséPereira, LilianaSantos-Buelga, CelestinoFerreira, Isabel C.F.R.2015-11-25T15:52:37Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/12421engPereira, Carla; Barros, Lillian; Alves, Maria José; Pereira, Liliana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw. Industrial Crops and Products. ISSN 0926-6690. 74, p. 412-4160926-669010.1016/j.indcrop.2015.05.056info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:28:35Zoai:bibliotecadigital.ipb.pt:10198/12421Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:02:34.548476Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
title |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
spellingShingle |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw Pereira, Carla Cochlospermum angolensis Infusion/pills/syrup Phenolic compounds Antimicrobial activity Clinical isolates |
title_short |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
title_full |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
title_fullStr |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
title_full_unstemmed |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
title_sort |
Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw |
author |
Pereira, Carla |
author_facet |
Pereira, Carla Barros, Lillian Alves, Maria José Pereira, Liliana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author_role |
author |
author2 |
Barros, Lillian Alves, Maria José Pereira, Liliana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Pereira, Carla Barros, Lillian Alves, Maria José Pereira, Liliana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
dc.subject.por.fl_str_mv |
Cochlospermum angolensis Infusion/pills/syrup Phenolic compounds Antimicrobial activity Clinical isolates |
topic |
Cochlospermum angolensis Infusion/pills/syrup Phenolic compounds Antimicrobial activity Clinical isolates |
description |
Three different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-25T15:52:37Z 2015 2015-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/12421 |
url |
http://hdl.handle.net/10198/12421 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Pereira, Carla; Barros, Lillian; Alves, Maria José; Pereira, Liliana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw. Industrial Crops and Products. ISSN 0926-6690. 74, p. 412-416 0926-6690 10.1016/j.indcrop.2015.05.056 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1817552222762827776 |