Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw

Detalhes bibliográficos
Autor(a) principal: Pereira, Carla
Data de Publicação: 2015
Outros Autores: Barros, Lillian, Alves, Maria José, Pereira, Liliana, Santos-Buelga, Celestino, Ferreira, Isabel C.F.R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/12421
Resumo: Three different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.
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spelling Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis WelwCochlospermum angolensisInfusion/pills/syrupPhenolic compoundsAntimicrobial activityClinical isolatesThree different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.The authors are grateful to Foundation for Science and Technology (FCT, Portugal) for financial support to the research center CIMO (strategic project PEst-OE/AGR/UI0690/2014) and L. Barros researcher contract under “Programa Compromisso com Ciência – 2008”.ElsevierBiblioteca Digital do IPBPereira, CarlaBarros, LillianAlves, Maria JoséPereira, LilianaSantos-Buelga, CelestinoFerreira, Isabel C.F.R.2015-11-25T15:52:37Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/12421engPereira, Carla; Barros, Lillian; Alves, Maria José; Pereira, Liliana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw. Industrial Crops and Products. ISSN 0926-6690. 74, p. 412-4160926-669010.1016/j.indcrop.2015.05.056info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:28:35Zoai:bibliotecadigital.ipb.pt:10198/12421Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:02:34.548476Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
title Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
spellingShingle Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
Pereira, Carla
Cochlospermum angolensis
Infusion/pills/syrup
Phenolic compounds
Antimicrobial activity
Clinical isolates
title_short Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
title_full Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
title_fullStr Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
title_full_unstemmed Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
title_sort Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw
author Pereira, Carla
author_facet Pereira, Carla
Barros, Lillian
Alves, Maria José
Pereira, Liliana
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
author_role author
author2 Barros, Lillian
Alves, Maria José
Pereira, Liliana
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Pereira, Carla
Barros, Lillian
Alves, Maria José
Pereira, Liliana
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
dc.subject.por.fl_str_mv Cochlospermum angolensis
Infusion/pills/syrup
Phenolic compounds
Antimicrobial activity
Clinical isolates
topic Cochlospermum angolensis
Infusion/pills/syrup
Phenolic compounds
Antimicrobial activity
Clinical isolates
description Three different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.
publishDate 2015
dc.date.none.fl_str_mv 2015-11-25T15:52:37Z
2015
2015-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/12421
url http://hdl.handle.net/10198/12421
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pereira, Carla; Barros, Lillian; Alves, Maria José; Pereira, Liliana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw. Industrial Crops and Products. ISSN 0926-6690. 74, p. 412-416
0926-6690
10.1016/j.indcrop.2015.05.056
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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