Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses

Detalhes bibliográficos
Autor(a) principal: Pimenta, José da Costa
Data de Publicação: 2021
Outros Autores: Saavedra, Maria José, Silva, Gabriela Jorge da, Cotovio, Mário
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/105312
https://doi.org/10.5455/OVJ.2021.v11.i4.9
Resumo: Many emergent pathogenic agents are cross-transmitted from animals to humans. Horses are considered as potential reservoirs of commensal, zoonotic, and multidrug-resistant bacteria. Equine bites could lead to infections caused by these agents, considering equine species as a public health concern. The more it is known about the equine oral microbiota the best secondary problems created by their commensal flora can be controlled. There are very few reports of Serratia rubidaea, a zoonotic and opportunistic bacterium, both in human and veterinary medicine. Aim: This study aimed to evaluate the Gram-negative microbiota of healthy equine oral cavities and their antimicrobial susceptibility. Methods: During equine routine oral procedures, eight healthy horses were selected for this study, after discarding any abnormal dental conditions. Samples were collected from the subgingival space and gingival margin from the tooth 406 and both the identification and antimicrobial susceptibility test of Gram-negative bacteria were performed. Results: This study reports the isolation of 32 Gram-negative agents, 27 of which were multidrug-resistant to the antimicrobial classes tested. High resistance rates were obtained to commonly used antimicrobial drugs, particularly macrolides and aminoglycosides as to carbapenems that are specific to human medicine. Two multi-drug resistance strains of S. rubidaea were found in the mouth of two healthy horses. Conclusion: Most Gram-negative isolates found in healthy horses were zoonotic and multi-drug resistant. This is a strong reason to consider the horse as an animal with a major place in the “One Health” concept. Equine clinicians should take precautions when working with horses’ mouths. Antimicrobial sensitivity tests should be taken into consideration when finding the appropriate antimicrobial therapy protocol. To the authors’ best knowledge, this is the first report about isolation of S. rubidaea from the mouth of the equine species.
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spelling Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horsesAntimicrobial ResistanceHorseOral microbiotaSerratiaAnimalsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHorsesSerratiaAnti-Infective AgentsMicrobiotaMany emergent pathogenic agents are cross-transmitted from animals to humans. Horses are considered as potential reservoirs of commensal, zoonotic, and multidrug-resistant bacteria. Equine bites could lead to infections caused by these agents, considering equine species as a public health concern. The more it is known about the equine oral microbiota the best secondary problems created by their commensal flora can be controlled. There are very few reports of Serratia rubidaea, a zoonotic and opportunistic bacterium, both in human and veterinary medicine. Aim: This study aimed to evaluate the Gram-negative microbiota of healthy equine oral cavities and their antimicrobial susceptibility. Methods: During equine routine oral procedures, eight healthy horses were selected for this study, after discarding any abnormal dental conditions. Samples were collected from the subgingival space and gingival margin from the tooth 406 and both the identification and antimicrobial susceptibility test of Gram-negative bacteria were performed. Results: This study reports the isolation of 32 Gram-negative agents, 27 of which were multidrug-resistant to the antimicrobial classes tested. High resistance rates were obtained to commonly used antimicrobial drugs, particularly macrolides and aminoglycosides as to carbapenems that are specific to human medicine. Two multi-drug resistance strains of S. rubidaea were found in the mouth of two healthy horses. Conclusion: Most Gram-negative isolates found in healthy horses were zoonotic and multi-drug resistant. This is a strong reason to consider the horse as an animal with a major place in the “One Health” concept. Equine clinicians should take precautions when working with horses’ mouths. Antimicrobial sensitivity tests should be taken into consideration when finding the appropriate antimicrobial therapy protocol. To the authors’ best knowledge, this is the first report about isolation of S. rubidaea from the mouth of the equine species.Faculty of Veterinary Journal, University of Tripoli2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/105312http://hdl.handle.net/10316/105312https://doi.org/10.5455/OVJ.2021.v11.i4.9eng2226-4485Pimenta, José da CostaSaavedra, Maria JoséSilva, Gabriela Jorge daCotovio, Márioinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-02-16T11:08:13Zoai:estudogeral.uc.pt:10316/105312Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:21:54.490420Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
title Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
spellingShingle Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
Pimenta, José da Costa
Antimicrobial Resistance
Horse
Oral microbiota
Serratia
Animals
Anti-Bacterial Agents
Drug Resistance, Multiple, Bacterial
Horses
Serratia
Anti-Infective Agents
Microbiota
title_short Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
title_full Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
title_fullStr Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
title_full_unstemmed Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
title_sort Multidrug-resistant Serratia rubidaea strains in the oral microbiota of healthy horses
author Pimenta, José da Costa
author_facet Pimenta, José da Costa
Saavedra, Maria José
Silva, Gabriela Jorge da
Cotovio, Mário
author_role author
author2 Saavedra, Maria José
Silva, Gabriela Jorge da
Cotovio, Mário
author2_role author
author
author
dc.contributor.author.fl_str_mv Pimenta, José da Costa
Saavedra, Maria José
Silva, Gabriela Jorge da
Cotovio, Mário
dc.subject.por.fl_str_mv Antimicrobial Resistance
Horse
Oral microbiota
Serratia
Animals
Anti-Bacterial Agents
Drug Resistance, Multiple, Bacterial
Horses
Serratia
Anti-Infective Agents
Microbiota
topic Antimicrobial Resistance
Horse
Oral microbiota
Serratia
Animals
Anti-Bacterial Agents
Drug Resistance, Multiple, Bacterial
Horses
Serratia
Anti-Infective Agents
Microbiota
description Many emergent pathogenic agents are cross-transmitted from animals to humans. Horses are considered as potential reservoirs of commensal, zoonotic, and multidrug-resistant bacteria. Equine bites could lead to infections caused by these agents, considering equine species as a public health concern. The more it is known about the equine oral microbiota the best secondary problems created by their commensal flora can be controlled. There are very few reports of Serratia rubidaea, a zoonotic and opportunistic bacterium, both in human and veterinary medicine. Aim: This study aimed to evaluate the Gram-negative microbiota of healthy equine oral cavities and their antimicrobial susceptibility. Methods: During equine routine oral procedures, eight healthy horses were selected for this study, after discarding any abnormal dental conditions. Samples were collected from the subgingival space and gingival margin from the tooth 406 and both the identification and antimicrobial susceptibility test of Gram-negative bacteria were performed. Results: This study reports the isolation of 32 Gram-negative agents, 27 of which were multidrug-resistant to the antimicrobial classes tested. High resistance rates were obtained to commonly used antimicrobial drugs, particularly macrolides and aminoglycosides as to carbapenems that are specific to human medicine. Two multi-drug resistance strains of S. rubidaea were found in the mouth of two healthy horses. Conclusion: Most Gram-negative isolates found in healthy horses were zoonotic and multi-drug resistant. This is a strong reason to consider the horse as an animal with a major place in the “One Health” concept. Equine clinicians should take precautions when working with horses’ mouths. Antimicrobial sensitivity tests should be taken into consideration when finding the appropriate antimicrobial therapy protocol. To the authors’ best knowledge, this is the first report about isolation of S. rubidaea from the mouth of the equine species.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/105312
http://hdl.handle.net/10316/105312
https://doi.org/10.5455/OVJ.2021.v11.i4.9
url http://hdl.handle.net/10316/105312
https://doi.org/10.5455/OVJ.2021.v11.i4.9
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2226-4485
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Faculty of Veterinary Journal, University of Tripoli
publisher.none.fl_str_mv Faculty of Veterinary Journal, University of Tripoli
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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