Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Mauer
Data de Publicação: 2024
Outros Autores: Pedro, João Mário, Silva, Carina, Magalhães, Pedro, Brito, Miguel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/16751
Resumo: The present study was supported by: Camões, Institute of Cooperation and Language, Portugal; Calouste Gulbenkian Foundation, Portugal; Government of Bengo Province, Angola; and the Angolan Ministry of Health.
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spelling Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy AngolansIndex of Cardiac Electrophysiological BalanceSmokingAngolaThe present study was supported by: Camões, Institute of Cooperation and Language, Portugal; Calouste Gulbenkian Foundation, Portugal; Government of Bengo Province, Angola; and the Angolan Ministry of Health.Background: Tobacco use accelerates atherosclerosis and is one of the predictors of death from ischemic heart disease, arrhythmias, heart failure, and sudden death. A new non-invasive parameter, the Index of Cardiac Electrophysiological Balance (iCEB) between depolarization and repolarization of the action potential, was considered a new biomarker for the identification of patients at increased arrhythmic risk. Objectives: We aimed to evaluate the iCEB in apparently healthy Angolans with habitual cigarette smoking compared to non-smokers. Subjects and methods: Data were obtained from the CardioBengo study, a cross-sectional community-based study in which a random sample of individuals aged between 15 and 84 years was selected. In total, 214 healthy subjects, 102 smokers, and 112 non-smokers in the same age group were included in the final analysis. Results: The average age of the participants was 42.17±13.04 years old and 26.6% of the sample was female. Smoking subjects had higher iCEB and corrected Index of Cardiac Electrophysiological Balance (iCEBc) values compared with non-smoking controls (4.39 vs. 4.25; p=0.024, respectively), and (4.74 vs. 4.57; p=0.030, respectively). Conclusions: In summary, iCEB and iCEBc were significantly higher in habitual smokers than in nonsmokers, which represents an increased risk of ventricular arrhythmogenesis in healthy habitual smokers. To the best of our knowledge, this is the first study performed in Africa to evaluate iCEB in smokers, making this type of study very important in low- and middle-income countries in the context of epidemiological transition.Magdi Yacoub InsituteRCIPLGonçalves, MauerPedro, João MárioSilva, CarinaMagalhães, PedroBrito, Miguel2024-01-03T12:26:22Z2024-012024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/16751engGonçalves M, Pedro JM, Silva C, Magalhães P, Brito M. Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans. Global Cardiol Sci Pract. 2024;2024(1):e202405.10.21542/gcsp.2024.5info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-06T02:15:59Zoai:repositorio.ipl.pt:10400.21/16751Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:31:12.499564Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
title Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
spellingShingle Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
Gonçalves, Mauer
Index of Cardiac Electrophysiological Balance
Smoking
Angola
title_short Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
title_full Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
title_fullStr Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
title_full_unstemmed Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
title_sort Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans
author Gonçalves, Mauer
author_facet Gonçalves, Mauer
Pedro, João Mário
Silva, Carina
Magalhães, Pedro
Brito, Miguel
author_role author
author2 Pedro, João Mário
Silva, Carina
Magalhães, Pedro
Brito, Miguel
author2_role author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Gonçalves, Mauer
Pedro, João Mário
Silva, Carina
Magalhães, Pedro
Brito, Miguel
dc.subject.por.fl_str_mv Index of Cardiac Electrophysiological Balance
Smoking
Angola
topic Index of Cardiac Electrophysiological Balance
Smoking
Angola
description The present study was supported by: Camões, Institute of Cooperation and Language, Portugal; Calouste Gulbenkian Foundation, Portugal; Government of Bengo Province, Angola; and the Angolan Ministry of Health.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-03T12:26:22Z
2024-01
2024-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/16751
url http://hdl.handle.net/10400.21/16751
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Gonçalves M, Pedro JM, Silva C, Magalhães P, Brito M. Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans. Global Cardiol Sci Pract. 2024;2024(1):e202405.
10.21542/gcsp.2024.5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Magdi Yacoub Insitute
publisher.none.fl_str_mv Magdi Yacoub Insitute
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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