Nutritional risks and colorectal cancer in a Portuguese population

Detalhes bibliográficos
Autor(a) principal: Ravasco, Paula
Data de Publicação: 2005
Outros Autores: Monteiro Grillo, isabel, Marques-Vidal, Pedro, Camilo, Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/47663
Resumo: Licencia creative commons: Open Access bajo la licencia Creative Commons 4.4 CC BY-NC-SA
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spelling Nutritional risks and colorectal cancer in a Portuguese populationColorectal cancerRisk factorsDietNutrientsAlcoholTobaccoLicencia creative commons: Open Access bajo la licencia Creative Commons 4.4 CC BY-NC-SABackground: Food and nutrition as major causes of colorectal cancer (CRC) are still debatable. Aim of the study: This cross-sectional study in a Portuguese population aimed to characterize and identify "high-risk" diets/life-styles and explore their associations with colorectal cancer. Methods: In 70 colorectal cancer patients and 70 sex, age-matched subjects without cancer history, we evaluated: diet history and detailed nutrient intake (DIET-PLAN5 2002, UK), alcohol (amount, type, years), smoking (number packages/year, years), physical activity, co-morbidities and body mass index. Age-adjusted Relative Risks were calculated, Proportional Hazards models adjusted the analysis for multiple risk factors. Results: Smoking was a risk factor (1.90). Increased colorectal cancer risk regarding the lowest vs the highest intake quartile emerged for: vitamin B12 (3.41), cholesterol (3.15), total fat (2.87), saturated fat (1.98), animal protein (1.95), energy (1.85), alcohol (1.70), iron (1.49), refined carbohydrates (1.39). Reduced colorectal cancer risk for the highest vs the lowest intake quartile was found for: n-3 fatty acids (0.10), insoluble fiber/folate (0.15), flavonoids/vitamin E (0.25), isoflavones/beta-carotene (0.30), selenium (0.36), copper (0.41), vitamin B6 (0.46). Conclusion: Our results corroborated well-established risk factors and identified emergent nutrients. Prolonged excessive intake of macronutrients and some micronutrients concurrent with marked deficits of fiber and protective compounds were dominant in colorectal cancer and more significant than alcohol and smoking. The interaction diet-colorectal cancer is consistent and the relevance of new nutrients is emerging.Arán EdicionesRepositório da Universidade de LisboaRavasco, PaulaMonteiro Grillo, isabelMarques-Vidal, PedroCamilo, Maria2021-05-05T14:43:05Z20052005-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/47663engNutr Hosp. 2005 May-Jun;20(3):165-1720212-1611info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:50:45Zoai:repositorio.ul.pt:10451/47663Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:59:40.155650Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nutritional risks and colorectal cancer in a Portuguese population
title Nutritional risks and colorectal cancer in a Portuguese population
spellingShingle Nutritional risks and colorectal cancer in a Portuguese population
Ravasco, Paula
Colorectal cancer
Risk factors
Diet
Nutrients
Alcohol
Tobacco
title_short Nutritional risks and colorectal cancer in a Portuguese population
title_full Nutritional risks and colorectal cancer in a Portuguese population
title_fullStr Nutritional risks and colorectal cancer in a Portuguese population
title_full_unstemmed Nutritional risks and colorectal cancer in a Portuguese population
title_sort Nutritional risks and colorectal cancer in a Portuguese population
author Ravasco, Paula
author_facet Ravasco, Paula
Monteiro Grillo, isabel
Marques-Vidal, Pedro
Camilo, Maria
author_role author
author2 Monteiro Grillo, isabel
Marques-Vidal, Pedro
Camilo, Maria
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Ravasco, Paula
Monteiro Grillo, isabel
Marques-Vidal, Pedro
Camilo, Maria
dc.subject.por.fl_str_mv Colorectal cancer
Risk factors
Diet
Nutrients
Alcohol
Tobacco
topic Colorectal cancer
Risk factors
Diet
Nutrients
Alcohol
Tobacco
description Licencia creative commons: Open Access bajo la licencia Creative Commons 4.4 CC BY-NC-SA
publishDate 2005
dc.date.none.fl_str_mv 2005
2005-01-01T00:00:00Z
2021-05-05T14:43:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/47663
url http://hdl.handle.net/10451/47663
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Nutr Hosp. 2005 May-Jun;20(3):165-172
0212-1611
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Arán Ediciones
publisher.none.fl_str_mv Arán Ediciones
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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