MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network

Detalhes bibliográficos
Autor(a) principal: Battista, Migliori, G
Data de Publicação: 2020
Outros Autores: Tiberi, S, Zumla, A, Petersen, E, Muhwa Chakaya, J, Wejse, C, Muñoz Torrico, M, Duarte, R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/143204
Resumo: The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities.
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spelling MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis NetworkDiagnosis; MDR-TB; Prevention; Rehabilitation of sequelae; Treatment; XDR-TBThe continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities.Elsevier20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/143204eng1201-971210.1016/j.ijid.2020.01.042Battista, Migliori, GTiberi, SZumla, APetersen, EMuhwa Chakaya, JWejse, CMuñoz Torrico, MDuarte, Rinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:09:35Zoai:repositorio-aberto.up.pt:10216/143204Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:17:03.955703Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
title MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
spellingShingle MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
Battista, Migliori, G
Diagnosis; MDR-TB; Prevention; Rehabilitation of sequelae; Treatment; XDR-TB
title_short MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
title_full MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
title_fullStr MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
title_full_unstemmed MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
title_sort MDR/XDR-TB management of patients and contacts: challenges facing the new decade The 2020 clinical update by the Global Tuberculosis Network
author Battista, Migliori, G
author_facet Battista, Migliori, G
Tiberi, S
Zumla, A
Petersen, E
Muhwa Chakaya, J
Wejse, C
Muñoz Torrico, M
Duarte, R
author_role author
author2 Tiberi, S
Zumla, A
Petersen, E
Muhwa Chakaya, J
Wejse, C
Muñoz Torrico, M
Duarte, R
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Battista, Migliori, G
Tiberi, S
Zumla, A
Petersen, E
Muhwa Chakaya, J
Wejse, C
Muñoz Torrico, M
Duarte, R
dc.subject.por.fl_str_mv Diagnosis; MDR-TB; Prevention; Rehabilitation of sequelae; Treatment; XDR-TB
topic Diagnosis; MDR-TB; Prevention; Rehabilitation of sequelae; Treatment; XDR-TB
description The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/143204
url https://hdl.handle.net/10216/143204
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1201-9712
10.1016/j.ijid.2020.01.042
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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