Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties

Detalhes bibliográficos
Autor(a) principal: Chantereau, Guillaume
Data de Publicação: 2019
Outros Autores: Brown, Nettie, Dourges, Marie-Anne, Freire, Carmen S. R., Silvestre, Armando J. D., Sebe, Gilles, Coma, Véronique
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/37483
Resumo: In this work, we report a convenient method of grafting non-leachable bioactive amine functions onto the surface of bacterial cellulose (BC) nanofibrils, via a simple silylation treatment in water. Two different silylation protocols, involving different solvents and post-treatments were envisaged and compared, using 3-aminopropyl-trimethoxysilane (APS) and (2-aminoethyl)-3-aminopropyl-trimethoxysilane (AEAPS) as silylating agents. In aqueous and controlled conditions, water-leaching resistant amino functions could be successfully introduced into BC, via a simple freeze-drying process. The silylated material remained highly porous, hygroscopic and displayed sufficient thermal stability to support the sterilization treatments generally required in medical applications. The impact of the silylation treatment on the intrinsic anti-bacterial properties of BC was investigated against the growth of Escherichia coli and Staphylococcus aureus. The results obtained after the in vitro studies revealed a significant growth reduction of S. aureus within the material.
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spelling Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial propertiesBacterial celluloseNanocelluloseAminosilaneAnti-bacterialSilylationIn this work, we report a convenient method of grafting non-leachable bioactive amine functions onto the surface of bacterial cellulose (BC) nanofibrils, via a simple silylation treatment in water. Two different silylation protocols, involving different solvents and post-treatments were envisaged and compared, using 3-aminopropyl-trimethoxysilane (APS) and (2-aminoethyl)-3-aminopropyl-trimethoxysilane (AEAPS) as silylating agents. In aqueous and controlled conditions, water-leaching resistant amino functions could be successfully introduced into BC, via a simple freeze-drying process. The silylated material remained highly porous, hygroscopic and displayed sufficient thermal stability to support the sterilization treatments generally required in medical applications. The impact of the silylation treatment on the intrinsic anti-bacterial properties of BC was investigated against the growth of Escherichia coli and Staphylococcus aureus. The results obtained after the in vitro studies revealed a significant growth reduction of S. aureus within the material.Elsevier2023-05-03T14:54:13Z2019-09-15T00:00:00Z2019-09-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/37483eng0144-861710.1016/j.carbpol.2019.05.009Chantereau, GuillaumeBrown, NettieDourges, Marie-AnneFreire, Carmen S. R.Silvestre, Armando J. D.Sebe, GillesComa, Véroniqueinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-06T04:45:34Zoai:ria.ua.pt:10773/37483Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-06T04:45:34Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
title Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
spellingShingle Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
Chantereau, Guillaume
Bacterial cellulose
Nanocellulose
Aminosilane
Anti-bacterial
Silylation
title_short Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
title_full Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
title_fullStr Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
title_full_unstemmed Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
title_sort Silylation of bacterial cellulose to design membranes with intrinsic anti-bacterial properties
author Chantereau, Guillaume
author_facet Chantereau, Guillaume
Brown, Nettie
Dourges, Marie-Anne
Freire, Carmen S. R.
Silvestre, Armando J. D.
Sebe, Gilles
Coma, Véronique
author_role author
author2 Brown, Nettie
Dourges, Marie-Anne
Freire, Carmen S. R.
Silvestre, Armando J. D.
Sebe, Gilles
Coma, Véronique
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Chantereau, Guillaume
Brown, Nettie
Dourges, Marie-Anne
Freire, Carmen S. R.
Silvestre, Armando J. D.
Sebe, Gilles
Coma, Véronique
dc.subject.por.fl_str_mv Bacterial cellulose
Nanocellulose
Aminosilane
Anti-bacterial
Silylation
topic Bacterial cellulose
Nanocellulose
Aminosilane
Anti-bacterial
Silylation
description In this work, we report a convenient method of grafting non-leachable bioactive amine functions onto the surface of bacterial cellulose (BC) nanofibrils, via a simple silylation treatment in water. Two different silylation protocols, involving different solvents and post-treatments were envisaged and compared, using 3-aminopropyl-trimethoxysilane (APS) and (2-aminoethyl)-3-aminopropyl-trimethoxysilane (AEAPS) as silylating agents. In aqueous and controlled conditions, water-leaching resistant amino functions could be successfully introduced into BC, via a simple freeze-drying process. The silylated material remained highly porous, hygroscopic and displayed sufficient thermal stability to support the sterilization treatments generally required in medical applications. The impact of the silylation treatment on the intrinsic anti-bacterial properties of BC was investigated against the growth of Escherichia coli and Staphylococcus aureus. The results obtained after the in vitro studies revealed a significant growth reduction of S. aureus within the material.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-15T00:00:00Z
2019-09-15
2023-05-03T14:54:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/37483
url http://hdl.handle.net/10773/37483
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0144-8617
10.1016/j.carbpol.2019.05.009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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