Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened

Detalhes bibliográficos
Autor(a) principal: Etibor, Temitope Akhigbe
Data de Publicação: 2023
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/152700
Resumo: Influenza A virus (IAV) is relevant to human and veterinary health as it causes seasonal epidemic and sporadic pandemics with excess mortality (Hampson and Mackenzie, 2006; Martin-Benito and Ortin, 2013; Vale-Costa et al., 2016a; Silvia Vale-Costa and Amorim, 2016). A way to reduce the risks of IAV disease is the yearly vaccination programmes, which has a reported 40-60% efficiency, pointing to the need for a more efficacious solution. This is only possible by gaining thorough understanding of IAV biology at the fundamental level, which could then inform the development of new antiviral therapeutics.
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spelling Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically HardenedInfluenzavirusDomínio/Área Científica::Ciências NaturaisInfluenza A virus (IAV) is relevant to human and veterinary health as it causes seasonal epidemic and sporadic pandemics with excess mortality (Hampson and Mackenzie, 2006; Martin-Benito and Ortin, 2013; Vale-Costa et al., 2016a; Silvia Vale-Costa and Amorim, 2016). A way to reduce the risks of IAV disease is the yearly vaccination programmes, which has a reported 40-60% efficiency, pointing to the need for a more efficacious solution. This is only possible by gaining thorough understanding of IAV biology at the fundamental level, which could then inform the development of new antiviral therapeutics.Amorim, Maria JoãoRUNEtibor, Temitope Akhigbe2023-03-282023-032026-02-28T00:00:00Z2023-03-28T00:00:00Zdoctoral thesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10362/152700TID:101736746enginfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:11:25Zoai:run.unl.pt:10362/152700Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:11:25Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
title Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
spellingShingle Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
Etibor, Temitope Akhigbe
Influenza
virus
Domínio/Área Científica::Ciências Naturais
title_short Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
title_full Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
title_fullStr Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
title_full_unstemmed Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
title_sort Influenza A virus Inclusions are Liquid Condensates that can be Pharmacologically Hardened
author Etibor, Temitope Akhigbe
author_facet Etibor, Temitope Akhigbe
author_role author
dc.contributor.none.fl_str_mv Amorim, Maria João
RUN
dc.contributor.author.fl_str_mv Etibor, Temitope Akhigbe
dc.subject.por.fl_str_mv Influenza
virus
Domínio/Área Científica::Ciências Naturais
topic Influenza
virus
Domínio/Área Científica::Ciências Naturais
description Influenza A virus (IAV) is relevant to human and veterinary health as it causes seasonal epidemic and sporadic pandemics with excess mortality (Hampson and Mackenzie, 2006; Martin-Benito and Ortin, 2013; Vale-Costa et al., 2016a; Silvia Vale-Costa and Amorim, 2016). A way to reduce the risks of IAV disease is the yearly vaccination programmes, which has a reported 40-60% efficiency, pointing to the need for a more efficacious solution. This is only possible by gaining thorough understanding of IAV biology at the fundamental level, which could then inform the development of new antiviral therapeutics.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-28
2023-03
2023-03-28T00:00:00Z
2026-02-28T00:00:00Z
dc.type.driver.fl_str_mv doctoral thesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/152700
TID:101736746
url http://hdl.handle.net/10362/152700
identifier_str_mv TID:101736746
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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