Total laryngectomy - Clinical outcomes and prognostic factors

Detalhes bibliográficos
Autor(a) principal: Pereira, Sónia
Data de Publicação: 2015
Outros Autores: Oliveira, Filipa, Costa, Eurico, Montalvão, Pedro, Magalhães, Miguel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.34631/sporl.583
Resumo: The choice between total laryngectomy (TL) and chemoradiotherapy in the treatment of advanced laryngeal and hypopharyngeal tumors remains controversial.Aiming to analyze clinical and functional outcomes of TL performed in our department, to identify prognostic factors and to verify the utility of computed tomography (CT) scan of the neck, we performed a retrospective study of TL performed between 2000 and 2004.From the 378 observed patients, most of them presented laryngeal tumors (72%) in advanced stage (90%). The CT scan of the neck allowed for correct staging in only 35% of the patients. The overall 5-year disease-specific survival rate was 59,5% and the prognostic factors identified were: laryngeal tumor, N0-N1 stage and previous tracheotomy.Given the high incidence of advanced tumors in our department and the limited value of neck CT scan, we recommend careful evaluation of such patients, in order to ensure adequate selection for chemoradiotherapy.
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spelling Total laryngectomy - Clinical outcomes and prognostic factorsLaringectomia total - Resultados clínicos e factores prognósticoslaryngeal and hypo pharyngeal tumorsadvanced stageCT scan of the necksurvivalprognostic factorstumores da laringe e hipofaringeestádio avançadotomografia computadorizada cervicalsobrevivênciafactores prognósticoThe choice between total laryngectomy (TL) and chemoradiotherapy in the treatment of advanced laryngeal and hypopharyngeal tumors remains controversial.Aiming to analyze clinical and functional outcomes of TL performed in our department, to identify prognostic factors and to verify the utility of computed tomography (CT) scan of the neck, we performed a retrospective study of TL performed between 2000 and 2004.From the 378 observed patients, most of them presented laryngeal tumors (72%) in advanced stage (90%). The CT scan of the neck allowed for correct staging in only 35% of the patients. The overall 5-year disease-specific survival rate was 59,5% and the prognostic factors identified were: laryngeal tumor, N0-N1 stage and previous tracheotomy.Given the high incidence of advanced tumors in our department and the limited value of neck CT scan, we recommend careful evaluation of such patients, in order to ensure adequate selection for chemoradiotherapy.A escolha entre laringectomia total (LT) e quimiorrradioterrapia no tratamento dos estadios avançados dos tumores da laringe e hipofaringe mantem-se controversa.No intuito de analisar resultados clínicos e funcionais das LT efectuadas no nosso serviço, avaliar eventuais factores com influência na sobrevivência e verificar o valor da tomografia computadorizada (TC) do pescoço no estadiamento, procedeu-se a estudo retrospectivo das LT efectuadas entre 2000 e 2004.Dos 378 processos observados, a maioria apresentava tumores da laringe (72%), em estadio avançado (90%). A TC cervical permitiu um estadiamento correcto em 35% (mais frequentemente subestadiamento). A sobrevivência doençaespecífica aos 5 anos foi 59,5% e os factores com influência na mesma foram: origem laríngea, estadio N0-N1 e traqueotomia prévia.Atendendo à elevada incidência de tumores em estadio avançado na nossa consulta e ao valor limitado da TC cervical, advoga-se atenção cuidada do Otorrinolaringologista por forma a garantir a selecção adequada dos doentes para quimiorradioterapia.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2015-12-08info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34631/sporl.583https://doi.org/10.34631/sporl.583Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 53 No. 2 (2015): Junho; 99-105Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 53 Núm. 2 (2015): Junho; 99-105Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 53 N.º 2 (2015): Junho; 99-1052184-6499reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://journalsporl.com/index.php/sporl/article/view/2749https://journalsporl.com/index.php/sporl/article/view/2749/752Pereira, SóniaOliveira, FilipaCosta, EuricoMontalvão, PedroMagalhães, Miguelinfo:eu-repo/semantics/openAccess2024-06-06T13:00:07Zoai:journalsporl.com:article/2749Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-06-06T13:00:07Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Total laryngectomy - Clinical outcomes and prognostic factors
Laringectomia total - Resultados clínicos e factores prognósticos
title Total laryngectomy - Clinical outcomes and prognostic factors
spellingShingle Total laryngectomy - Clinical outcomes and prognostic factors
Pereira, Sónia
laryngeal and hypo pharyngeal tumors
advanced stage
CT scan of the neck
survival
prognostic factors
tumores da laringe e hipofaringe
estádio avançado
tomografia computadorizada cervical
sobrevivência
factores prognóstico
title_short Total laryngectomy - Clinical outcomes and prognostic factors
title_full Total laryngectomy - Clinical outcomes and prognostic factors
title_fullStr Total laryngectomy - Clinical outcomes and prognostic factors
title_full_unstemmed Total laryngectomy - Clinical outcomes and prognostic factors
title_sort Total laryngectomy - Clinical outcomes and prognostic factors
author Pereira, Sónia
author_facet Pereira, Sónia
Oliveira, Filipa
Costa, Eurico
Montalvão, Pedro
Magalhães, Miguel
author_role author
author2 Oliveira, Filipa
Costa, Eurico
Montalvão, Pedro
Magalhães, Miguel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Sónia
Oliveira, Filipa
Costa, Eurico
Montalvão, Pedro
Magalhães, Miguel
dc.subject.por.fl_str_mv laryngeal and hypo pharyngeal tumors
advanced stage
CT scan of the neck
survival
prognostic factors
tumores da laringe e hipofaringe
estádio avançado
tomografia computadorizada cervical
sobrevivência
factores prognóstico
topic laryngeal and hypo pharyngeal tumors
advanced stage
CT scan of the neck
survival
prognostic factors
tumores da laringe e hipofaringe
estádio avançado
tomografia computadorizada cervical
sobrevivência
factores prognóstico
description The choice between total laryngectomy (TL) and chemoradiotherapy in the treatment of advanced laryngeal and hypopharyngeal tumors remains controversial.Aiming to analyze clinical and functional outcomes of TL performed in our department, to identify prognostic factors and to verify the utility of computed tomography (CT) scan of the neck, we performed a retrospective study of TL performed between 2000 and 2004.From the 378 observed patients, most of them presented laryngeal tumors (72%) in advanced stage (90%). The CT scan of the neck allowed for correct staging in only 35% of the patients. The overall 5-year disease-specific survival rate was 59,5% and the prognostic factors identified were: laryngeal tumor, N0-N1 stage and previous tracheotomy.Given the high incidence of advanced tumors in our department and the limited value of neck CT scan, we recommend careful evaluation of such patients, in order to ensure adequate selection for chemoradiotherapy.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-08
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.34631/sporl.583
https://doi.org/10.34631/sporl.583
url https://doi.org/10.34631/sporl.583
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://journalsporl.com/index.php/sporl/article/view/2749
https://journalsporl.com/index.php/sporl/article/view/2749/752
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
dc.source.none.fl_str_mv Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 53 No. 2 (2015): Junho; 99-105
Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 53 Núm. 2 (2015): Junho; 99-105
Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 53 N.º 2 (2015): Junho; 99-105
2184-6499
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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