Approach to paraneoplastic hyperhidrosis in palliative care: a literature review

• Autor(a) principal: Ribeiro, Sandra
• Data de Publicação: 2023
• Outros Autores: Pinto Sousa, Sara Inês, Moutinho Ferreira , Sara Alexandra, Sapateiro Luis , Michael
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.31877/on.2023.47.01
• topic: Hipersudorese; Hiperidrose; Cuidados paliativos; Medicina paliativa; Cuidados de conforto; Sweating; Hyperhidrosis; Palliative Care; Palliative Medicine; Hospice Care

Introduction: This article reviews the current scientific evidence on the approach to paraneoplastic hyperhidrosis in patients receiving palliative care. Methods: Our search was conducted in MEDLINE/Pubmed®, Cochrane, DARE®, BMJ EBM®, NICE®, CMAJ® and Bandolier, using the MeSH terms “Sweating”, “Hyperhidrosis”, “Palliative Care”, and “Palliative Medicine”. We used the Oxford scale to assess the quality of the included studies. Results: This review includes 13 articles on the therapeutic approach to paraneoplastic hyperhidrosis using the following interventions: thioridazine, thalidomide, olanzapine, gabapentin, cannabinoids, acupuncture and Chinese herbal medicine. We obtained heterogeneous results and, while these interventions are in general beneficial for controlling paraneoplastic hyperhidrosis in palliative care, no robust evidence exists that unequivocally demonstrates one approach is more beneficial than another. Conclusions: At present, the available evidence on the therapeutic approach to paraneoplastic hyperhidrosis in palliative care has low quality (Level of Evidence 4; Strength of Recommendation C).