Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement

Detalhes bibliográficos
Autor(a) principal: Lopes, Sofia
Data de Publicação: 2018
Outros Autores: Vide, Júlia, Magina, Sofia, Cunha, Ana Paula, Azevedo, Filomena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.76.4.952
Resumo: Pyoderma gangrenosum is a chronic inflammatory disease characterized by the development of a painful deep ulcer with undermined borders. Head and neck are rarely affected regions of the body and also usually associated with a worse prognosis. Corticosteroids are the mainstay of treatment although available options are not specific nor completely effective in pyoderma gangrenosum. We report the case of a 46-year-old patient with an aggressive orbital pyoderma gangrenosum with progressive extension to the central nervous system and insufficient response to treatment, ultimately leading to patient’s death.
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spelling Fatal Orbital Pyoderma Gangrenosum with Central Nervous System InvolvementPioderma Gangrenoso Orbitário Fatal com Envolvimento do Sistema Nervoso CentralCentral Nervous System DiseasesOrbital DiseasesPyoderma GangrenosumDoenças OrbitáriasDoenças do Sistema Nervoso CentralPioderma GangrenosoPyoderma gangrenosum is a chronic inflammatory disease characterized by the development of a painful deep ulcer with undermined borders. Head and neck are rarely affected regions of the body and also usually associated with a worse prognosis. Corticosteroids are the mainstay of treatment although available options are not specific nor completely effective in pyoderma gangrenosum. We report the case of a 46-year-old patient with an aggressive orbital pyoderma gangrenosum with progressive extension to the central nervous system and insufficient response to treatment, ultimately leading to patient’s death.O pioderma gangrenoso é uma doença inflamatória crónica que se caracteriza pelo desenvolvimento de uma úlcera dolorosa e profunda com bordos mal delimitados. Cabeça e pescoço são regiões anatómicas raramente atingidas e geralmente associadas a um pior prognóstico. A corticoterapia é a base do tratamento desta dermatose, embora as opções disponíveis não sejam específicas nem inteiramente eficazes no pioderma gangrenoso. Relatamos o caso de um doente de 46 anos com pioderma gangrenoso orbitário de caráter agressivo, com extensão progressiva ao sistema nervoso central e resposta insuficiente ao tratamento, que culminou na morte do doente.Sociedade Portuguesa de Dermatologia e Venereologia2018-12-27T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfimage/jpegimage/jpegimage/jpegimage/jpeghttps://doi.org/10.29021/spdv.76.4.952oai:ojs.revista.spdv.com.pt:article/952Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 4 (2018): October - December; 435-438Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 4 (2018): Outubro - Dezembro; 435-4382182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spdv.com.pt/index.php/spdv/article/view/952https://doi.org/10.29021/spdv.76.4.952https://revista.spdv.com.pt/index.php/spdv/article/view/952/607https://revista.spdv.com.pt/index.php/spdv/article/view/952/750https://revista.spdv.com.pt/index.php/spdv/article/view/952/753https://revista.spdv.com.pt/index.php/spdv/article/view/952/754https://revista.spdv.com.pt/index.php/spdv/article/view/952/764Lopes, SofiaVide, JúliaMagina, SofiaCunha, Ana PaulaAzevedo, Filomenainfo:eu-repo/semantics/openAccess2022-10-06T12:35:09Zoai:ojs.revista.spdv.com.pt:article/952Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:07.669009Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
Pioderma Gangrenoso Orbitário Fatal com Envolvimento do Sistema Nervoso Central
title Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
spellingShingle Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
Lopes, Sofia
Central Nervous System Diseases
Orbital Diseases
Pyoderma Gangrenosum
Doenças Orbitárias
Doenças do Sistema Nervoso Central
Pioderma Gangrenoso
title_short Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
title_full Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
title_fullStr Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
title_full_unstemmed Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
title_sort Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
author Lopes, Sofia
author_facet Lopes, Sofia
Vide, Júlia
Magina, Sofia
Cunha, Ana Paula
Azevedo, Filomena
author_role author
author2 Vide, Júlia
Magina, Sofia
Cunha, Ana Paula
Azevedo, Filomena
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Sofia
Vide, Júlia
Magina, Sofia
Cunha, Ana Paula
Azevedo, Filomena
dc.subject.por.fl_str_mv Central Nervous System Diseases
Orbital Diseases
Pyoderma Gangrenosum
Doenças Orbitárias
Doenças do Sistema Nervoso Central
Pioderma Gangrenoso
topic Central Nervous System Diseases
Orbital Diseases
Pyoderma Gangrenosum
Doenças Orbitárias
Doenças do Sistema Nervoso Central
Pioderma Gangrenoso
description Pyoderma gangrenosum is a chronic inflammatory disease characterized by the development of a painful deep ulcer with undermined borders. Head and neck are rarely affected regions of the body and also usually associated with a worse prognosis. Corticosteroids are the mainstay of treatment although available options are not specific nor completely effective in pyoderma gangrenosum. We report the case of a 46-year-old patient with an aggressive orbital pyoderma gangrenosum with progressive extension to the central nervous system and insufficient response to treatment, ultimately leading to patient’s death.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-27T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.76.4.952
oai:ojs.revista.spdv.com.pt:article/952
url https://doi.org/10.29021/spdv.76.4.952
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/952
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/952
https://doi.org/10.29021/spdv.76.4.952
https://revista.spdv.com.pt/index.php/spdv/article/view/952/607
https://revista.spdv.com.pt/index.php/spdv/article/view/952/750
https://revista.spdv.com.pt/index.php/spdv/article/view/952/753
https://revista.spdv.com.pt/index.php/spdv/article/view/952/754
https://revista.spdv.com.pt/index.php/spdv/article/view/952/764
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
image/jpeg
image/jpeg
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image/jpeg
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 4 (2018): October - December; 435-438
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 4 (2018): Outubro - Dezembro; 435-438
2182-2409
2182-2395
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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