Detecting traces of 17α-ethinylestradiol in complex water matrices

Detalhes bibliográficos
Autor(a) principal: Zagalo, Paulo Morgado
Data de Publicação: 2020
Outros Autores: Ribeiro, Paulo António, Raposo, Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/114273
Resumo: PTDC/FIS-NAN/0909/2014 UID/FIS/00068/2019
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spelling Detecting traces of 17α-ethinylestradiol in complex water matricesCapacitanceEE2Electric modulusHormoneImpedanceInterdigitated electrodesLayer-by-layer filmsLoss tangentPCASensorAnalytical ChemistryBiochemistryAtomic and Molecular Physics, and OpticsInstrumentationElectrical and Electronic EngineeringPTDC/FIS-NAN/0909/2014 UID/FIS/00068/2019Hormones have a harmful impact on the environment and their detection in water bodies is an urgent matter. In this work, we present and analyze a sensor device able to detect traces of the synthetic hormone 17α-ethinylestradiol (EE2) below 10−9 M in media of different complexities, namely, ultrapure, mineral and tap waters. This device consists of solid supports with interdigitated electrodes without and with a polyethylenimine (PEI) and poly (sodium 4-styrenesulfonate) (PSS) layer-by-layer film deposited on it. Device response was evaluated through capacitance, loss tangent and electric modulus spectra and the data were analyzed by principal component analysis method. While the three types of spectra were demonstrated to be able to clearly discriminate the different media, loss tangent spectra allow for the detection of EE2 concentration, with a sensitivity of −0.072 ± 0.009 and −0.44 ± 0.03 per decade of concentration, for mineral and tap water, respectively. Detection limits values were found to be lower than the ones present in the literature and presenting values of 8.6 fM (2.6 pg/L) and of 7.5 fM (22.2 pg/L) for tap and mineral waters, respectively. Moreover, the obtained response values follow the same behavior with EE2 concentration in any medium, meaning that loss tangent spectra allow the quantification of EE2 concentration in aqueous complex matrices.CeFITec – Centro de Física e Investigação TecnológicaDF – Departamento de FísicaRUNZagalo, Paulo MorgadoRibeiro, Paulo AntónioRaposo, Maria2021-03-22T23:27:23Z2020-12-022020-12-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article14application/pdfhttp://hdl.handle.net/10362/114273eng1424-8220PURE: 27345646https://doi.org/10.3390/s20247324info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:56:54Zoai:run.unl.pt:10362/114273Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:28.610379Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Detecting traces of 17α-ethinylestradiol in complex water matrices
title Detecting traces of 17α-ethinylestradiol in complex water matrices
spellingShingle Detecting traces of 17α-ethinylestradiol in complex water matrices
Zagalo, Paulo Morgado
Capacitance
EE2
Electric modulus
Hormone
Impedance
Interdigitated electrodes
Layer-by-layer films
Loss tangent
PCA
Sensor
Analytical Chemistry
Biochemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Electrical and Electronic Engineering
title_short Detecting traces of 17α-ethinylestradiol in complex water matrices
title_full Detecting traces of 17α-ethinylestradiol in complex water matrices
title_fullStr Detecting traces of 17α-ethinylestradiol in complex water matrices
title_full_unstemmed Detecting traces of 17α-ethinylestradiol in complex water matrices
title_sort Detecting traces of 17α-ethinylestradiol in complex water matrices
author Zagalo, Paulo Morgado
author_facet Zagalo, Paulo Morgado
Ribeiro, Paulo António
Raposo, Maria
author_role author
author2 Ribeiro, Paulo António
Raposo, Maria
author2_role author
author
dc.contributor.none.fl_str_mv CeFITec – Centro de Física e Investigação Tecnológica
DF – Departamento de Física
RUN
dc.contributor.author.fl_str_mv Zagalo, Paulo Morgado
Ribeiro, Paulo António
Raposo, Maria
dc.subject.por.fl_str_mv Capacitance
EE2
Electric modulus
Hormone
Impedance
Interdigitated electrodes
Layer-by-layer films
Loss tangent
PCA
Sensor
Analytical Chemistry
Biochemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Electrical and Electronic Engineering
topic Capacitance
EE2
Electric modulus
Hormone
Impedance
Interdigitated electrodes
Layer-by-layer films
Loss tangent
PCA
Sensor
Analytical Chemistry
Biochemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Electrical and Electronic Engineering
description PTDC/FIS-NAN/0909/2014 UID/FIS/00068/2019
publishDate 2020
dc.date.none.fl_str_mv 2020-12-02
2020-12-02T00:00:00Z
2021-03-22T23:27:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/114273
url http://hdl.handle.net/10362/114273
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1424-8220
PURE: 27345646
https://doi.org/10.3390/s20247324
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 14
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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