Oxidative stress in relation to aging and exercise
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/44676 |
Resumo: | Definition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age. |
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Oxidative stress in relation to aging and exerciseOxidative stressAgingExerciseGlutathioneSuperoxide dismutaseReactive oxygen speciesAntioxidantsCortisolStress oxidativoEnvelhecimentoExercício físicoSuperóxido dismutaseEspécies reativas de oxigénioAntioxidantesHidrocortisonaDefinition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age.MDPIRepositório ComumVerhaegen, DimphnaSmits, KellyOsório, NádiaCaseiro, Armando2023-04-28T15:56:16Z2022-08-252022-08-25T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/44676eng2673-8392https://doi.org/10.3390/ encyclopedia2030105info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-05-04T02:15:23Zoai:comum.rcaap.pt:10400.26/44676Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:50:31.126654Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Oxidative stress in relation to aging and exercise |
title |
Oxidative stress in relation to aging and exercise |
spellingShingle |
Oxidative stress in relation to aging and exercise Verhaegen, Dimphna Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
title_short |
Oxidative stress in relation to aging and exercise |
title_full |
Oxidative stress in relation to aging and exercise |
title_fullStr |
Oxidative stress in relation to aging and exercise |
title_full_unstemmed |
Oxidative stress in relation to aging and exercise |
title_sort |
Oxidative stress in relation to aging and exercise |
author |
Verhaegen, Dimphna |
author_facet |
Verhaegen, Dimphna Smits, Kelly Osório, Nádia Caseiro, Armando |
author_role |
author |
author2 |
Smits, Kelly Osório, Nádia Caseiro, Armando |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Verhaegen, Dimphna Smits, Kelly Osório, Nádia Caseiro, Armando |
dc.subject.por.fl_str_mv |
Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
topic |
Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
description |
Definition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-25 2022-08-25T00:00:00Z 2023-04-28T15:56:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/44676 |
url |
http://hdl.handle.net/10400.26/44676 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2673-8392 https://doi.org/10.3390/ encyclopedia2030105 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131584719224832 |