Fattymess: fat diet-induced obesity in melanoma metastasis

Detalhes bibliográficos
Autor(a) principal: Correia, Joana
Data de Publicação: 2022
Outros Autores: Costa, Raquel, Prudêncio, Cristina, Soares, Raquel, Coelho, Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/23959
Resumo: Melanoma is the most aggressive skin cancer characterized by a high metastatic potential and poor survival rate, leading to major morbidity/mortality. Overweight, obesity and diet composition have been identified as risk factors for many types of cancers. However, there are cancers where obesity is associated with favorable outcomes and this has been coined the “obesity paradox”. Preliminary data obtained by our research group disclosed paradoxical findings unveiling that obesity act as a two-edged sword in melanoma: potentiating primary tumor growth, and vascularity/angiogenesis, but at the same time decrease metastatic potential, thus preventing secondary tumor growth. In this exploratory research project, we propose to further explore and deepen the impact that fat-rich diets and obesity partake in melanoma etiology
id RCAP_ff849f0842acb39c7be04e906f38653d
oai_identifier_str oai:recipp.ipp.pt:10400.22/23959
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Fattymess: fat diet-induced obesity in melanoma metastasisMelanoma is the most aggressive skin cancer characterized by a high metastatic potential and poor survival rate, leading to major morbidity/mortality. Overweight, obesity and diet composition have been identified as risk factors for many types of cancers. However, there are cancers where obesity is associated with favorable outcomes and this has been coined the “obesity paradox”. Preliminary data obtained by our research group disclosed paradoxical findings unveiling that obesity act as a two-edged sword in melanoma: potentiating primary tumor growth, and vascularity/angiogenesis, but at the same time decrease metastatic potential, thus preventing secondary tumor growth. In this exploratory research project, we propose to further explore and deepen the impact that fat-rich diets and obesity partake in melanoma etiologyESS | P. PORTO EdiçõesRepositório Científico do Instituto Politécnico do PortoCorreia, JoanaCosta, RaquelPrudêncio, CristinaSoares, RaquelCoelho, Pedro2023-11-23T14:42:14Z2022-012022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/23959engCorreia, J., Costa, R., Prudêncio, C., Soares, R., & Coelho, P. (2022). Fattymess: Fat diet-induced obesity in melanoma metastasis. Atas Do I Encontro de Investigação Da Escola Superior de Saúde Do Politécnico Do Porto, Pp. 3-8, ESS | P. PORTO Edições, 141–148. https://doi.org/10.26537/recipp-23959978-989-9045-31-6 e.ISBN 978-989-9045-30-910.26537/recipp-23959info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T01:47:43Zoai:recipp.ipp.pt:10400.22/23959Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:19:59.304907Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fattymess: fat diet-induced obesity in melanoma metastasis
title Fattymess: fat diet-induced obesity in melanoma metastasis
spellingShingle Fattymess: fat diet-induced obesity in melanoma metastasis
Correia, Joana
title_short Fattymess: fat diet-induced obesity in melanoma metastasis
title_full Fattymess: fat diet-induced obesity in melanoma metastasis
title_fullStr Fattymess: fat diet-induced obesity in melanoma metastasis
title_full_unstemmed Fattymess: fat diet-induced obesity in melanoma metastasis
title_sort Fattymess: fat diet-induced obesity in melanoma metastasis
author Correia, Joana
author_facet Correia, Joana
Costa, Raquel
Prudêncio, Cristina
Soares, Raquel
Coelho, Pedro
author_role author
author2 Costa, Raquel
Prudêncio, Cristina
Soares, Raquel
Coelho, Pedro
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Correia, Joana
Costa, Raquel
Prudêncio, Cristina
Soares, Raquel
Coelho, Pedro
description Melanoma is the most aggressive skin cancer characterized by a high metastatic potential and poor survival rate, leading to major morbidity/mortality. Overweight, obesity and diet composition have been identified as risk factors for many types of cancers. However, there are cancers where obesity is associated with favorable outcomes and this has been coined the “obesity paradox”. Preliminary data obtained by our research group disclosed paradoxical findings unveiling that obesity act as a two-edged sword in melanoma: potentiating primary tumor growth, and vascularity/angiogenesis, but at the same time decrease metastatic potential, thus preventing secondary tumor growth. In this exploratory research project, we propose to further explore and deepen the impact that fat-rich diets and obesity partake in melanoma etiology
publishDate 2022
dc.date.none.fl_str_mv 2022-01
2022-01-01T00:00:00Z
2023-11-23T14:42:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/23959
url http://hdl.handle.net/10400.22/23959
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Correia, J., Costa, R., Prudêncio, C., Soares, R., & Coelho, P. (2022). Fattymess: Fat diet-induced obesity in melanoma metastasis. Atas Do I Encontro de Investigação Da Escola Superior de Saúde Do Politécnico Do Porto, Pp. 3-8, ESS | P. PORTO Edições, 141–148. https://doi.org/10.26537/recipp-23959
978-989-9045-31-6 e.ISBN 978-989-9045-30-9
10.26537/recipp-23959
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv ESS | P. PORTO Edições
publisher.none.fl_str_mv ESS | P. PORTO Edições
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799135499072307200

Registros relacionados