Peri-operative management of a pregnant patient with hereditary angioedema submitted to a cesarean-section: case report

• Autor(a) principal: Estevens,Teresa Maria Ramos Nunes
• Data de Publicação: 2020
• Outros Autores: Serrano,Angel, Amaro,Solange, Ribeiro,João
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista Brasileira de Anestesiologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942020000100048
• topic: Hereditary angioedema; Anesthetic management; Pregnant patient; Cesarean section

Abstract Hereditary angioedema is an autosomal dominant disorder, presenting as sudden and recurring episodes of variable severity of subcutaneous and mucosa edema that may occur spontaneously or in response to triggers. There are three knwon types of hereditary angioedema. The disorder is caused by decrease in the plasma level or change in the functional capacity of C1 inhibitor, with increase in bradykinin and in vascular permeability, and consequent edema. Several measures are required in the perioperative period in order to avoid an acute attack. Prophylaxis should be carried out throughout pregnancy before any surgical procedure, before dental procedures, upon airway handling, on patients with previous episodes of angioedema, and when there are significant changes in volemia. The literature is scarce in regard to the association between hereditary angioedema and pregnancy. We describe a successful case of a pregnant patient with type I hereditary angioedema submitted to a C-section.