Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Anestesiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000300231 |
Resumo: | ABSTRACT Colonoscopy is one of the most common procedures. Sedation and analgesia decrease anxiety and discomfort and minimize risks. Therefore, patients prefer to be sedated when undergoing examination, although the best combination of drugs has not been determined. The combination of opioids and benzodiazepines is used to relieve the patient's pain and discomfort. More recently, propofol has assumed a prominent position. This randomized prospective study is unique in medical literature that specifically compared the use of propofol and fentanyl with or without midazolam for colonoscopy sedation performed by anesthesiologists. The aim of this study was to evaluate the side effects of sedation, discharge conditions, quality of sedation, and propofol consumption during colonoscopy, with or without midazolam as preanesthetic. The study involved 140 patients who underwent colonoscopy at the University Hospital of the Federal University of Juiz de Fora. Patients were divided into two groups: Group I received intravenous midazolam as preanesthetic 5 min before sedation, followed by fentanyl and propofol; Group II received intravenous anesthesia with fentanyl and propofol. Patients in Group II had a higher incidence of reaction (motor or verbal) to the colonoscope introduction, bradycardia, hypotension, and increased propofol consumption. Patient satisfaction was higher in Group I. According to the methodology used, the combination of midazolam, fentanyl, and propofol for colonoscopy sedation reduces propofol consumption and provides greater patient satisfaction. |
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Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolamSedationColonoscopyPropofolFentanilMidazolamABSTRACT Colonoscopy is one of the most common procedures. Sedation and analgesia decrease anxiety and discomfort and minimize risks. Therefore, patients prefer to be sedated when undergoing examination, although the best combination of drugs has not been determined. The combination of opioids and benzodiazepines is used to relieve the patient's pain and discomfort. More recently, propofol has assumed a prominent position. This randomized prospective study is unique in medical literature that specifically compared the use of propofol and fentanyl with or without midazolam for colonoscopy sedation performed by anesthesiologists. The aim of this study was to evaluate the side effects of sedation, discharge conditions, quality of sedation, and propofol consumption during colonoscopy, with or without midazolam as preanesthetic. The study involved 140 patients who underwent colonoscopy at the University Hospital of the Federal University of Juiz de Fora. Patients were divided into two groups: Group I received intravenous midazolam as preanesthetic 5 min before sedation, followed by fentanyl and propofol; Group II received intravenous anesthesia with fentanyl and propofol. Patients in Group II had a higher incidence of reaction (motor or verbal) to the colonoscope introduction, bradycardia, hypotension, and increased propofol consumption. Patient satisfaction was higher in Group I. According to the methodology used, the combination of midazolam, fentanyl, and propofol for colonoscopy sedation reduces propofol consumption and provides greater patient satisfaction.Sociedade Brasileira de Anestesiologia2016-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000300231Revista Brasileira de Anestesiologia v.66 n.3 2016reponame:Revista Brasileira de Anestesiologia (Online)instname:Sociedade Brasileira de Anestesiologia (SBA)instacron:SBA10.1016/j.bjane.2014.09.014info:eu-repo/semantics/openAccessNeves,Jose Francisco Nunes Pereira dasAraújo,Mariana Moraes Pereira das NevesAraújo,Fernando de PaivaFerreira,Clarice MartinsDuarte,Fabiana Baeta NevesPace,Fabio HelenoOrnellas,Laura CottaBaron,Todd H.Ferreira,Lincoln Eduardo Villela Vieira de Castroeng2016-05-30T00:00:00Zoai:scielo:S0034-70942016000300231Revistahttps://www.sbahq.org/revista/https://old.scielo.br/oai/scielo-oai.php||sba2000@openlink.com.br1806-907X0034-7094opendoar:2016-05-30T00:00Revista Brasileira de Anestesiologia (Online) - Sociedade Brasileira de Anestesiologia (SBA)false |
dc.title.none.fl_str_mv |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
title |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
spellingShingle |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam Neves,Jose Francisco Nunes Pereira das Sedation Colonoscopy Propofol Fentanil Midazolam |
title_short |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
title_full |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
title_fullStr |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
title_full_unstemmed |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
title_sort |
Colonoscopy sedation: clinical trial comparing propofol and fentanyl with or without midazolam |
author |
Neves,Jose Francisco Nunes Pereira das |
author_facet |
Neves,Jose Francisco Nunes Pereira das Araújo,Mariana Moraes Pereira das Neves Araújo,Fernando de Paiva Ferreira,Clarice Martins Duarte,Fabiana Baeta Neves Pace,Fabio Heleno Ornellas,Laura Cotta Baron,Todd H. Ferreira,Lincoln Eduardo Villela Vieira de Castro |
author_role |
author |
author2 |
Araújo,Mariana Moraes Pereira das Neves Araújo,Fernando de Paiva Ferreira,Clarice Martins Duarte,Fabiana Baeta Neves Pace,Fabio Heleno Ornellas,Laura Cotta Baron,Todd H. Ferreira,Lincoln Eduardo Villela Vieira de Castro |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Neves,Jose Francisco Nunes Pereira das Araújo,Mariana Moraes Pereira das Neves Araújo,Fernando de Paiva Ferreira,Clarice Martins Duarte,Fabiana Baeta Neves Pace,Fabio Heleno Ornellas,Laura Cotta Baron,Todd H. Ferreira,Lincoln Eduardo Villela Vieira de Castro |
dc.subject.por.fl_str_mv |
Sedation Colonoscopy Propofol Fentanil Midazolam |
topic |
Sedation Colonoscopy Propofol Fentanil Midazolam |
description |
ABSTRACT Colonoscopy is one of the most common procedures. Sedation and analgesia decrease anxiety and discomfort and minimize risks. Therefore, patients prefer to be sedated when undergoing examination, although the best combination of drugs has not been determined. The combination of opioids and benzodiazepines is used to relieve the patient's pain and discomfort. More recently, propofol has assumed a prominent position. This randomized prospective study is unique in medical literature that specifically compared the use of propofol and fentanyl with or without midazolam for colonoscopy sedation performed by anesthesiologists. The aim of this study was to evaluate the side effects of sedation, discharge conditions, quality of sedation, and propofol consumption during colonoscopy, with or without midazolam as preanesthetic. The study involved 140 patients who underwent colonoscopy at the University Hospital of the Federal University of Juiz de Fora. Patients were divided into two groups: Group I received intravenous midazolam as preanesthetic 5 min before sedation, followed by fentanyl and propofol; Group II received intravenous anesthesia with fentanyl and propofol. Patients in Group II had a higher incidence of reaction (motor or verbal) to the colonoscope introduction, bradycardia, hypotension, and increased propofol consumption. Patient satisfaction was higher in Group I. According to the methodology used, the combination of midazolam, fentanyl, and propofol for colonoscopy sedation reduces propofol consumption and provides greater patient satisfaction. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000300231 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000300231 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjane.2014.09.014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Anestesiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Anestesiologia |
dc.source.none.fl_str_mv |
Revista Brasileira de Anestesiologia v.66 n.3 2016 reponame:Revista Brasileira de Anestesiologia (Online) instname:Sociedade Brasileira de Anestesiologia (SBA) instacron:SBA |
instname_str |
Sociedade Brasileira de Anestesiologia (SBA) |
instacron_str |
SBA |
institution |
SBA |
reponame_str |
Revista Brasileira de Anestesiologia (Online) |
collection |
Revista Brasileira de Anestesiologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Anestesiologia (Online) - Sociedade Brasileira de Anestesiologia (SBA) |
repository.mail.fl_str_mv |
||sba2000@openlink.com.br |
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1752126628676239360 |