Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections

Detalhes bibliográficos
Autor(a) principal: Oliveira,Alexandre Faraco de
Data de Publicação: 2014
Outros Autores: Oliveira Filho,Horácio de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Vascular Brasileiro (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000400289
Resumo: Introduction:Diabetic foot infections are a difficult problem to solve, often requiring hospitalization and exposing patients to the risk of amputations. Identification of the most prevalent pathogens is useful for administration of antibiotic therapy, and can reduce mutilations.Objective:To identify the microbiological profile and resistance to antimicrobial drugs in a series of patients with infected diabetic feet.Material and methods:an epidemiological, retrospective and descriptive study based on analysis of medical records from diabetic patients with plantar lesions who underwent surgical treatment over a 24-month period at a public hospital. Data were collected on age, sex, length of hospital stay, cultures from lesions, antibiotic therapy administered, bacterial resistance and surgeries conducted, with statistical analysis of means and standard deviations.Results:There were 66 admissions of diabetic patients, the majority elderly people (77%). Hospital stays ranged from 2 to 29 days, with a mean of 12.42. There were 91 surgical procedures, resulting in some kind of amputation in 65% of cases. The most common bacterial group was enterobacteria (47%), followed by staphylococci (27%). Three patients (4.5%) had multi-resistant organisms. Resistance to clindamycin was the most common at 39 admissions (59%), followed by resistance to cephalexin, seen in 24 admissions (36%).Conclusions:Diabetic foot infections were most often caused by germs found in the community, in particular the enterococci. Bacterial resistance was very widespread and was most commonly associated with drugs for oral administration, in particular clindamycin and cephalexin.
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spelling Microbiological species and antimicrobial resistance profile in patients with diabetic foot infectionsdiabetic footbacterial drug resistancediabetes complicationsIntroduction:Diabetic foot infections are a difficult problem to solve, often requiring hospitalization and exposing patients to the risk of amputations. Identification of the most prevalent pathogens is useful for administration of antibiotic therapy, and can reduce mutilations.Objective:To identify the microbiological profile and resistance to antimicrobial drugs in a series of patients with infected diabetic feet.Material and methods:an epidemiological, retrospective and descriptive study based on analysis of medical records from diabetic patients with plantar lesions who underwent surgical treatment over a 24-month period at a public hospital. Data were collected on age, sex, length of hospital stay, cultures from lesions, antibiotic therapy administered, bacterial resistance and surgeries conducted, with statistical analysis of means and standard deviations.Results:There were 66 admissions of diabetic patients, the majority elderly people (77%). Hospital stays ranged from 2 to 29 days, with a mean of 12.42. There were 91 surgical procedures, resulting in some kind of amputation in 65% of cases. The most common bacterial group was enterobacteria (47%), followed by staphylococci (27%). Three patients (4.5%) had multi-resistant organisms. Resistance to clindamycin was the most common at 39 admissions (59%), followed by resistance to cephalexin, seen in 24 admissions (36%).Conclusions:Diabetic foot infections were most often caused by germs found in the community, in particular the enterococci. Bacterial resistance was very widespread and was most commonly associated with drugs for oral administration, in particular clindamycin and cephalexin.Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000400289Jornal Vascular Brasileiro v.13 n.4 2014reponame:Jornal Vascular Brasileiro (Online)instname:Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)instacron:SBACV10.1590/1677-5449.0015info:eu-repo/semantics/openAccessOliveira,Alexandre Faraco deOliveira Filho,Horácio deeng2015-09-15T00:00:00Zoai:scielo:S1677-54492014000400289Revistahttp://www.scielo.br/jvbhttps://old.scielo.br/oai/scielo-oai.php||secretaria@sbacv.org.br1677-73011677-5449opendoar:2015-09-15T00:00Jornal Vascular Brasileiro (Online) - Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)false
dc.title.none.fl_str_mv Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
title Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
spellingShingle Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
Oliveira,Alexandre Faraco de
diabetic foot
bacterial drug resistance
diabetes complications
title_short Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
title_full Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
title_fullStr Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
title_full_unstemmed Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
title_sort Microbiological species and antimicrobial resistance profile in patients with diabetic foot infections
author Oliveira,Alexandre Faraco de
author_facet Oliveira,Alexandre Faraco de
Oliveira Filho,Horácio de
author_role author
author2 Oliveira Filho,Horácio de
author2_role author
dc.contributor.author.fl_str_mv Oliveira,Alexandre Faraco de
Oliveira Filho,Horácio de
dc.subject.por.fl_str_mv diabetic foot
bacterial drug resistance
diabetes complications
topic diabetic foot
bacterial drug resistance
diabetes complications
description Introduction:Diabetic foot infections are a difficult problem to solve, often requiring hospitalization and exposing patients to the risk of amputations. Identification of the most prevalent pathogens is useful for administration of antibiotic therapy, and can reduce mutilations.Objective:To identify the microbiological profile and resistance to antimicrobial drugs in a series of patients with infected diabetic feet.Material and methods:an epidemiological, retrospective and descriptive study based on analysis of medical records from diabetic patients with plantar lesions who underwent surgical treatment over a 24-month period at a public hospital. Data were collected on age, sex, length of hospital stay, cultures from lesions, antibiotic therapy administered, bacterial resistance and surgeries conducted, with statistical analysis of means and standard deviations.Results:There were 66 admissions of diabetic patients, the majority elderly people (77%). Hospital stays ranged from 2 to 29 days, with a mean of 12.42. There were 91 surgical procedures, resulting in some kind of amputation in 65% of cases. The most common bacterial group was enterobacteria (47%), followed by staphylococci (27%). Three patients (4.5%) had multi-resistant organisms. Resistance to clindamycin was the most common at 39 admissions (59%), followed by resistance to cephalexin, seen in 24 admissions (36%).Conclusions:Diabetic foot infections were most often caused by germs found in the community, in particular the enterococci. Bacterial resistance was very widespread and was most commonly associated with drugs for oral administration, in particular clindamycin and cephalexin.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000400289
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000400289
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1677-5449.0015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
publisher.none.fl_str_mv Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
dc.source.none.fl_str_mv Jornal Vascular Brasileiro v.13 n.4 2014
reponame:Jornal Vascular Brasileiro (Online)
instname:Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
instacron:SBACV
instname_str Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
instacron_str SBACV
institution SBACV
reponame_str Jornal Vascular Brasileiro (Online)
collection Jornal Vascular Brasileiro (Online)
repository.name.fl_str_mv Jornal Vascular Brasileiro (Online) - Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
repository.mail.fl_str_mv ||secretaria@sbacv.org.br
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