Off-label prescriptions in diabetic foot

Detalhes bibliográficos
Autor(a) principal: Andrade,Luís Jesuíno de Oliveira
Data de Publicação: 2014
Outros Autores: França,Larissa Santos, Melo,Paulo Roberto Santana de, Araújo,Marcelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Vascular Brasileiro (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192
Resumo: Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.
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spelling Off-label prescriptions in diabetic footoff-label usediabetic footdiabetes mellitusPrescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192Jornal Vascular Brasileiro v.13 n.3 2014reponame:Jornal Vascular Brasileiro (Online)instname:Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)instacron:SBACV10.1590/jvb.2014.025info:eu-repo/semantics/openAccessAndrade,Luís Jesuíno de OliveiraFrança,Larissa SantosMelo,Paulo Roberto Santana deAraújo,Marceloeng2015-09-15T00:00:00Zoai:scielo:S1677-54492014000300192Revistahttp://www.scielo.br/jvbhttps://old.scielo.br/oai/scielo-oai.php||secretaria@sbacv.org.br1677-73011677-5449opendoar:2015-09-15T00:00Jornal Vascular Brasileiro (Online) - Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)false
dc.title.none.fl_str_mv Off-label prescriptions in diabetic foot
title Off-label prescriptions in diabetic foot
spellingShingle Off-label prescriptions in diabetic foot
Andrade,Luís Jesuíno de Oliveira
off-label use
diabetic foot
diabetes mellitus
title_short Off-label prescriptions in diabetic foot
title_full Off-label prescriptions in diabetic foot
title_fullStr Off-label prescriptions in diabetic foot
title_full_unstemmed Off-label prescriptions in diabetic foot
title_sort Off-label prescriptions in diabetic foot
author Andrade,Luís Jesuíno de Oliveira
author_facet Andrade,Luís Jesuíno de Oliveira
França,Larissa Santos
Melo,Paulo Roberto Santana de
Araújo,Marcelo
author_role author
author2 França,Larissa Santos
Melo,Paulo Roberto Santana de
Araújo,Marcelo
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade,Luís Jesuíno de Oliveira
França,Larissa Santos
Melo,Paulo Roberto Santana de
Araújo,Marcelo
dc.subject.por.fl_str_mv off-label use
diabetic foot
diabetes mellitus
topic off-label use
diabetic foot
diabetes mellitus
description Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.
publishDate 2014
dc.date.none.fl_str_mv 2014-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/jvb.2014.025
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
publisher.none.fl_str_mv Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
dc.source.none.fl_str_mv Jornal Vascular Brasileiro v.13 n.3 2014
reponame:Jornal Vascular Brasileiro (Online)
instname:Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
instacron:SBACV
instname_str Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
instacron_str SBACV
institution SBACV
reponame_str Jornal Vascular Brasileiro (Online)
collection Jornal Vascular Brasileiro (Online)
repository.name.fl_str_mv Jornal Vascular Brasileiro (Online) - Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
repository.mail.fl_str_mv ||secretaria@sbacv.org.br
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