Degree of Agreement between Cardiovascular Risk Stratification Tools
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Cardiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000500427 |
Resumo: | Abstract Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Brazil, and primary prevention care may be guided by risk stratification tools. The Framingham (FRS) and QRISK-2 (QRS) risk scores estimate 10-year overall cardiovascular risk in asymptomatic individuals, but the instrument of choice may lead to different therapeutic strategies. Objective: To evaluate the degree of agreement between FRS and QRS in 10-year overall cardiovascular risk stratification in disease-free individuals. Methods: Cross-sectional, observational, descriptive and analytical study in a convenience sample of 74 individuals attending the outpatient care service of a university hospital in Brazil between January 2014 and January 2015. After application of FRS and QRS, patients were classified in low/moderate risk (< 20%) or high risk (≥ 20%). Results: The proportion of individuals classified as at high risk was higher in FRS than in QRS (33.7% vs 21.6%). A synergic effect of male gender with systemic arterial hypertension was observed in both tools, and with for geriatric age group in QRS (p < 0.05) in high-risk stratum. The Kappa index was 0.519 (95%CI = 0.386-0.652; p < 0.001) between both instruments. Conclusion: There was a moderate agreement between FRS and QRS in estimating 10-year overall cardiovascular risk. The risk scores used in this study can identify synergism between variables, and their behavior is influenced by the population in which it was derived. It is important to recognize the need for calibrating risk scores for the Brazilian population. |
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Degree of Agreement between Cardiovascular Risk Stratification ToolsCardiovascular Diseases / mortalityCardiovascular Diseases / morbidityRisk AssessmentCardiovascular Diseases / epidemiologyPeriod AnalysisAbstract Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Brazil, and primary prevention care may be guided by risk stratification tools. The Framingham (FRS) and QRISK-2 (QRS) risk scores estimate 10-year overall cardiovascular risk in asymptomatic individuals, but the instrument of choice may lead to different therapeutic strategies. Objective: To evaluate the degree of agreement between FRS and QRS in 10-year overall cardiovascular risk stratification in disease-free individuals. Methods: Cross-sectional, observational, descriptive and analytical study in a convenience sample of 74 individuals attending the outpatient care service of a university hospital in Brazil between January 2014 and January 2015. After application of FRS and QRS, patients were classified in low/moderate risk (< 20%) or high risk (≥ 20%). Results: The proportion of individuals classified as at high risk was higher in FRS than in QRS (33.7% vs 21.6%). A synergic effect of male gender with systemic arterial hypertension was observed in both tools, and with for geriatric age group in QRS (p < 0.05) in high-risk stratum. The Kappa index was 0.519 (95%CI = 0.386-0.652; p < 0.001) between both instruments. Conclusion: There was a moderate agreement between FRS and QRS in estimating 10-year overall cardiovascular risk. The risk scores used in this study can identify synergism between variables, and their behavior is influenced by the population in which it was derived. It is important to recognize the need for calibrating risk scores for the Brazilian population.Sociedade Brasileira de Cardiologia - SBC2017-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000500427Arquivos Brasileiros de Cardiologia v.108 n.5 2017reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20170057info:eu-repo/semantics/openAccessGarcia,Guilherme ThoméStamm,Ana Maria Nunes de FariaRosa,Ariel CórdovaMarasciulo,Antônio CarlosMarasciulo,Rodrigo ConillBattistella,CristianRemor,Alexandre Augusto de Costaeng2017-07-05T00:00:00Zoai:scielo:S0066-782X2017000500427Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2017-07-05T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
title |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
spellingShingle |
Degree of Agreement between Cardiovascular Risk Stratification Tools Garcia,Guilherme Thomé Cardiovascular Diseases / mortality Cardiovascular Diseases / morbidity Risk Assessment Cardiovascular Diseases / epidemiology Period Analysis |
title_short |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
title_full |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
title_fullStr |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
title_full_unstemmed |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
title_sort |
Degree of Agreement between Cardiovascular Risk Stratification Tools |
author |
Garcia,Guilherme Thomé |
author_facet |
Garcia,Guilherme Thomé Stamm,Ana Maria Nunes de Faria Rosa,Ariel Córdova Marasciulo,Antônio Carlos Marasciulo,Rodrigo Conill Battistella,Cristian Remor,Alexandre Augusto de Costa |
author_role |
author |
author2 |
Stamm,Ana Maria Nunes de Faria Rosa,Ariel Córdova Marasciulo,Antônio Carlos Marasciulo,Rodrigo Conill Battistella,Cristian Remor,Alexandre Augusto de Costa |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Garcia,Guilherme Thomé Stamm,Ana Maria Nunes de Faria Rosa,Ariel Córdova Marasciulo,Antônio Carlos Marasciulo,Rodrigo Conill Battistella,Cristian Remor,Alexandre Augusto de Costa |
dc.subject.por.fl_str_mv |
Cardiovascular Diseases / mortality Cardiovascular Diseases / morbidity Risk Assessment Cardiovascular Diseases / epidemiology Period Analysis |
topic |
Cardiovascular Diseases / mortality Cardiovascular Diseases / morbidity Risk Assessment Cardiovascular Diseases / epidemiology Period Analysis |
description |
Abstract Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Brazil, and primary prevention care may be guided by risk stratification tools. The Framingham (FRS) and QRISK-2 (QRS) risk scores estimate 10-year overall cardiovascular risk in asymptomatic individuals, but the instrument of choice may lead to different therapeutic strategies. Objective: To evaluate the degree of agreement between FRS and QRS in 10-year overall cardiovascular risk stratification in disease-free individuals. Methods: Cross-sectional, observational, descriptive and analytical study in a convenience sample of 74 individuals attending the outpatient care service of a university hospital in Brazil between January 2014 and January 2015. After application of FRS and QRS, patients were classified in low/moderate risk (< 20%) or high risk (≥ 20%). Results: The proportion of individuals classified as at high risk was higher in FRS than in QRS (33.7% vs 21.6%). A synergic effect of male gender with systemic arterial hypertension was observed in both tools, and with for geriatric age group in QRS (p < 0.05) in high-risk stratum. The Kappa index was 0.519 (95%CI = 0.386-0.652; p < 0.001) between both instruments. Conclusion: There was a moderate agreement between FRS and QRS in estimating 10-year overall cardiovascular risk. The risk scores used in this study can identify synergism between variables, and their behavior is influenced by the population in which it was derived. It is important to recognize the need for calibrating risk scores for the Brazilian population. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-05-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000500427 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000500427 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20170057 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.108 n.5 2017 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
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1752126567245414400 |