Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography
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Publication Date: | 2016 |
Other Authors: | , , , , |
Format: | Article |
Language: | eng |
Source: | Arquivos Brasileiros de Cardiologia (Online) |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300299 |
Summary: | Abstract Background: Only a small proportion of patients referred for coronary angiography with suspected coronary artery disease (CAD) have the diagnosis of obstructive CAD confirmed by the exam. For this reason, further strategies for risk stratification are necessary. Objective: To investigate the relationship of the presence of fragmented QRS (fQRS) on admission electrocardiogram with angiographically detected CAD and CAD severity in patients without known vascular diseases and myocardial fibrosis, undergoing first diagnostic coronary angiography. Methods: We enrolled 336 consecutive patients undergoing coronary angiography for suspected CAD. The patients were divided into two groups according to the presence or absence of fQRS on admission. We compared the groups regarding the presence and severity of CAD. Results: Seventy-nine (23.5%) patients had fQRS on admission. There was not a statistically significant difference between patients with fQRS (41.8%) and non-fQRS (30.4%), regarding the presence of CAD (p = 0.059). However, there was a statistically significant difference between patients with fQRS and non-fQRS regarding the presence of stenotic CAD (40.5% vs. 10.5%, p<0.001) and multi vessel disease (25,3% vs. 5.1%, p<0.001). The frequency of fQRS was significantly higher in patients with SYNTAX score >22 compared to patients with SYNTAX score ≤22. Conclusions: Our findings suggest that fQRS may be an indicator of early-stage myocardial damage preceding the appearance of fibrosis and scar, and may be used for risk stratification in patients undergoing first diagnostic coronary angiography |
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Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary AngiographyCoronary Artery DiseaseCoronary AngiographyElectrocardiographyFragmented QRSSYNTAX scoreAbstract Background: Only a small proportion of patients referred for coronary angiography with suspected coronary artery disease (CAD) have the diagnosis of obstructive CAD confirmed by the exam. For this reason, further strategies for risk stratification are necessary. Objective: To investigate the relationship of the presence of fragmented QRS (fQRS) on admission electrocardiogram with angiographically detected CAD and CAD severity in patients without known vascular diseases and myocardial fibrosis, undergoing first diagnostic coronary angiography. Methods: We enrolled 336 consecutive patients undergoing coronary angiography for suspected CAD. The patients were divided into two groups according to the presence or absence of fQRS on admission. We compared the groups regarding the presence and severity of CAD. Results: Seventy-nine (23.5%) patients had fQRS on admission. There was not a statistically significant difference between patients with fQRS (41.8%) and non-fQRS (30.4%), regarding the presence of CAD (p = 0.059). However, there was a statistically significant difference between patients with fQRS and non-fQRS regarding the presence of stenotic CAD (40.5% vs. 10.5%, p<0.001) and multi vessel disease (25,3% vs. 5.1%, p<0.001). The frequency of fQRS was significantly higher in patients with SYNTAX score >22 compared to patients with SYNTAX score ≤22. Conclusions: Our findings suggest that fQRS may be an indicator of early-stage myocardial damage preceding the appearance of fibrosis and scar, and may be used for risk stratification in patients undergoing first diagnostic coronary angiographySociedade Brasileira de Cardiologia - SBC2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300299Arquivos Brasileiros de Cardiologia v.107 n.4 2016reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20160139info:eu-repo/semantics/openAccessEyuboglu,MehmetEkinci,Mehmet AkifKarakoyun,Suleymankucuk,UgurSenarslan,OmerAkdeniz,Bahrieng2016-11-09T00:00:00Zoai:scielo:S0066-782X2016004300299Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2016-11-09T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
title |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
spellingShingle |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography Eyuboglu,Mehmet Coronary Artery Disease Coronary Angiography Electrocardiography Fragmented QRS SYNTAX score |
title_short |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
title_full |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
title_fullStr |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
title_full_unstemmed |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
title_sort |
Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography |
author |
Eyuboglu,Mehmet |
author_facet |
Eyuboglu,Mehmet Ekinci,Mehmet Akif Karakoyun,Suleyman kucuk,Ugur Senarslan,Omer Akdeniz,Bahri |
author_role |
author |
author2 |
Ekinci,Mehmet Akif Karakoyun,Suleyman kucuk,Ugur Senarslan,Omer Akdeniz,Bahri |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Eyuboglu,Mehmet Ekinci,Mehmet Akif Karakoyun,Suleyman kucuk,Ugur Senarslan,Omer Akdeniz,Bahri |
dc.subject.por.fl_str_mv |
Coronary Artery Disease Coronary Angiography Electrocardiography Fragmented QRS SYNTAX score |
topic |
Coronary Artery Disease Coronary Angiography Electrocardiography Fragmented QRS SYNTAX score |
description |
Abstract Background: Only a small proportion of patients referred for coronary angiography with suspected coronary artery disease (CAD) have the diagnosis of obstructive CAD confirmed by the exam. For this reason, further strategies for risk stratification are necessary. Objective: To investigate the relationship of the presence of fragmented QRS (fQRS) on admission electrocardiogram with angiographically detected CAD and CAD severity in patients without known vascular diseases and myocardial fibrosis, undergoing first diagnostic coronary angiography. Methods: We enrolled 336 consecutive patients undergoing coronary angiography for suspected CAD. The patients were divided into two groups according to the presence or absence of fQRS on admission. We compared the groups regarding the presence and severity of CAD. Results: Seventy-nine (23.5%) patients had fQRS on admission. There was not a statistically significant difference between patients with fQRS (41.8%) and non-fQRS (30.4%), regarding the presence of CAD (p = 0.059). However, there was a statistically significant difference between patients with fQRS and non-fQRS regarding the presence of stenotic CAD (40.5% vs. 10.5%, p<0.001) and multi vessel disease (25,3% vs. 5.1%, p<0.001). The frequency of fQRS was significantly higher in patients with SYNTAX score >22 compared to patients with SYNTAX score ≤22. Conclusions: Our findings suggest that fQRS may be an indicator of early-stage myocardial damage preceding the appearance of fibrosis and scar, and may be used for risk stratification in patients undergoing first diagnostic coronary angiography |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300299 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016004300299 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20160139 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.107 n.4 2016 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
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1752126566310084608 |