Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy

Detalhes bibliográficos
Autor(a) principal: Fragata,Claudia da Silva
Data de Publicação: 2015
Outros Autores: Matsumoto,Afonso Y., Ramires,Felix J. A., Fernandes,Fabio, Buck,Paula de Cássia, Salemi,Vera Maria C., Nastari,Luciano, Mady,Charles, Ianni,Barbara Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Cardiologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000028
Resumo: Background:Chagas disease is a cause of dilated cardiomyopathy, and information about left atrial (LA) function in this disease still lacks.Objective:To assess the different LA functions (reservoir, conduit and pump functions) and their correlation with the echocardiographic parameters of left ventricular (LV) systolic and diastolic functions.Methods:10 control subjects (CG), and patients with Chagas disease as follows: 26 with the indeterminate form (GI); 30 with ECG alterations (GII); and 19 with LV dysfunction (GIII). All patients underwent M-mode and two-dimensional echocardiography, pulsed-wave Doppler and tissue Doppler imaging.Results:Reservoir function (Total Emptying Fraction: TEF): (p <0.0001), lower in GIII as compared to CG (p = 0.003), GI (p <0.001) and GII (p <0.001). Conduit function (Passive Emptying Fraction: PEF): (p = 0.004), lower in GIII (GIII and CG, p = 0.06; GI and GII, p = 0.06; and GII and GIII, p = 0.07). Pump function (Active Emptying Fraction: AEF): (p = 0.0001), lower in GIII as compared to CG (p = 0.05), GI (p<0.0001) and GII (p = 0.002). There was a negative correlation of E/e’average with the reservoir and pump functions (TEF and AEF), and a positive correlation of e’average with s’ wave (both septal and lateral walls) and the reservoir, conduit and pump LA functions.Conclusion:An impairment of LA functions in Chagas cardiomyopathy was observed.
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spelling Left Atrial Function in Patients with Chronic Chagasic CardiomyopathyChagas DiseaseChagas CardiomyopathyVentricular DysfunctionAtrial Function/physiopathologyEchocardiographyDoppler/methodsBackground:Chagas disease is a cause of dilated cardiomyopathy, and information about left atrial (LA) function in this disease still lacks.Objective:To assess the different LA functions (reservoir, conduit and pump functions) and their correlation with the echocardiographic parameters of left ventricular (LV) systolic and diastolic functions.Methods:10 control subjects (CG), and patients with Chagas disease as follows: 26 with the indeterminate form (GI); 30 with ECG alterations (GII); and 19 with LV dysfunction (GIII). All patients underwent M-mode and two-dimensional echocardiography, pulsed-wave Doppler and tissue Doppler imaging.Results:Reservoir function (Total Emptying Fraction: TEF): (p <0.0001), lower in GIII as compared to CG (p = 0.003), GI (p <0.001) and GII (p <0.001). Conduit function (Passive Emptying Fraction: PEF): (p = 0.004), lower in GIII (GIII and CG, p = 0.06; GI and GII, p = 0.06; and GII and GIII, p = 0.07). Pump function (Active Emptying Fraction: AEF): (p = 0.0001), lower in GIII as compared to CG (p = 0.05), GI (p<0.0001) and GII (p = 0.002). There was a negative correlation of E/e’average with the reservoir and pump functions (TEF and AEF), and a positive correlation of e’average with s’ wave (both septal and lateral walls) and the reservoir, conduit and pump LA functions.Conclusion:An impairment of LA functions in Chagas cardiomyopathy was observed.Sociedade Brasileira de Cardiologia - SBC2015-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000028Arquivos Brasileiros de Cardiologia v.105 n.1 2015reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20150045info:eu-repo/semantics/openAccessFragata,Claudia da SilvaMatsumoto,Afonso Y.Ramires,Felix J. A.Fernandes,FabioBuck,Paula de CássiaSalemi,Vera Maria C.Nastari,LucianoMady,CharlesIanni,Barbara Mariaeng2015-10-19T00:00:00Zoai:scielo:S0066-782X2015002000028Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2015-10-19T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false
dc.title.none.fl_str_mv Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
title Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
spellingShingle Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
Fragata,Claudia da Silva
Chagas Disease
Chagas Cardiomyopathy
Ventricular Dysfunction
Atrial Function/physiopathology
Echocardiography
Doppler/methods
title_short Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
title_full Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
title_fullStr Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
title_full_unstemmed Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
title_sort Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy
author Fragata,Claudia da Silva
author_facet Fragata,Claudia da Silva
Matsumoto,Afonso Y.
Ramires,Felix J. A.
Fernandes,Fabio
Buck,Paula de Cássia
Salemi,Vera Maria C.
Nastari,Luciano
Mady,Charles
Ianni,Barbara Maria
author_role author
author2 Matsumoto,Afonso Y.
Ramires,Felix J. A.
Fernandes,Fabio
Buck,Paula de Cássia
Salemi,Vera Maria C.
Nastari,Luciano
Mady,Charles
Ianni,Barbara Maria
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fragata,Claudia da Silva
Matsumoto,Afonso Y.
Ramires,Felix J. A.
Fernandes,Fabio
Buck,Paula de Cássia
Salemi,Vera Maria C.
Nastari,Luciano
Mady,Charles
Ianni,Barbara Maria
dc.subject.por.fl_str_mv Chagas Disease
Chagas Cardiomyopathy
Ventricular Dysfunction
Atrial Function/physiopathology
Echocardiography
Doppler/methods
topic Chagas Disease
Chagas Cardiomyopathy
Ventricular Dysfunction
Atrial Function/physiopathology
Echocardiography
Doppler/methods
description Background:Chagas disease is a cause of dilated cardiomyopathy, and information about left atrial (LA) function in this disease still lacks.Objective:To assess the different LA functions (reservoir, conduit and pump functions) and their correlation with the echocardiographic parameters of left ventricular (LV) systolic and diastolic functions.Methods:10 control subjects (CG), and patients with Chagas disease as follows: 26 with the indeterminate form (GI); 30 with ECG alterations (GII); and 19 with LV dysfunction (GIII). All patients underwent M-mode and two-dimensional echocardiography, pulsed-wave Doppler and tissue Doppler imaging.Results:Reservoir function (Total Emptying Fraction: TEF): (p <0.0001), lower in GIII as compared to CG (p = 0.003), GI (p <0.001) and GII (p <0.001). Conduit function (Passive Emptying Fraction: PEF): (p = 0.004), lower in GIII (GIII and CG, p = 0.06; GI and GII, p = 0.06; and GII and GIII, p = 0.07). Pump function (Active Emptying Fraction: AEF): (p = 0.0001), lower in GIII as compared to CG (p = 0.05), GI (p<0.0001) and GII (p = 0.002). There was a negative correlation of E/e’average with the reservoir and pump functions (TEF and AEF), and a positive correlation of e’average with s’ wave (both septal and lateral walls) and the reservoir, conduit and pump LA functions.Conclusion:An impairment of LA functions in Chagas cardiomyopathy was observed.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/abc.20150045
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
dc.source.none.fl_str_mv Arquivos Brasileiros de Cardiologia v.105 n.1 2015
reponame:Arquivos Brasileiros de Cardiologia (Online)
instname:Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
instname_str Sociedade Brasileira de Cardiologia (SBC)
instacron_str SBC
institution SBC
reponame_str Arquivos Brasileiros de Cardiologia (Online)
collection Arquivos Brasileiros de Cardiologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)
repository.mail.fl_str_mv ||arquivos@cardiol.br
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