Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Cardiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420 |
Resumo: | Abstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers. |
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Arquivos Brasileiros de Cardiologia (Online) |
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Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography AngiographyCardiovascular Diseases/mortalityPlaque, AtheroscleroticCoronary Artery Disease/diagnosisCalcium SignalingCoronary, AngiotomographyRisk FactorsAbstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers.Sociedade Brasileira de Cardiologia - SBC2018-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420Arquivos Brasileiros de Cardiologia v.110 n.5 2018reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20180063info:eu-repo/semantics/openAccessGabriel,Fabíola SantosGonçalves,Luiz Flávio GalvãoMelo,Enaldo Vieira deSousa,Antônio Carlos SobralPinto,Ibraim Masciarelli FranciscoSantana,Sara Melo MacedoMatos,Carlos José Oliveira deSouto,Maria Júlia SilveiraConceição,Flávio Mateus do SacramentoOliveira,Joselina Luzia Menezeseng2018-05-30T00:00:00Zoai:scielo:S0066-782X2018000500420Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2018-05-30T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
title |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
spellingShingle |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography Gabriel,Fabíola Santos Cardiovascular Diseases/mortality Plaque, Atherosclerotic Coronary Artery Disease/diagnosis Calcium Signaling Coronary, Angiotomography Risk Factors |
title_short |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
title_full |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
title_fullStr |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
title_full_unstemmed |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
title_sort |
Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography |
author |
Gabriel,Fabíola Santos |
author_facet |
Gabriel,Fabíola Santos Gonçalves,Luiz Flávio Galvão Melo,Enaldo Vieira de Sousa,Antônio Carlos Sobral Pinto,Ibraim Masciarelli Francisco Santana,Sara Melo Macedo Matos,Carlos José Oliveira de Souto,Maria Júlia Silveira Conceição,Flávio Mateus do Sacramento Oliveira,Joselina Luzia Menezes |
author_role |
author |
author2 |
Gonçalves,Luiz Flávio Galvão Melo,Enaldo Vieira de Sousa,Antônio Carlos Sobral Pinto,Ibraim Masciarelli Francisco Santana,Sara Melo Macedo Matos,Carlos José Oliveira de Souto,Maria Júlia Silveira Conceição,Flávio Mateus do Sacramento Oliveira,Joselina Luzia Menezes |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Gabriel,Fabíola Santos Gonçalves,Luiz Flávio Galvão Melo,Enaldo Vieira de Sousa,Antônio Carlos Sobral Pinto,Ibraim Masciarelli Francisco Santana,Sara Melo Macedo Matos,Carlos José Oliveira de Souto,Maria Júlia Silveira Conceição,Flávio Mateus do Sacramento Oliveira,Joselina Luzia Menezes |
dc.subject.por.fl_str_mv |
Cardiovascular Diseases/mortality Plaque, Atherosclerotic Coronary Artery Disease/diagnosis Calcium Signaling Coronary, Angiotomography Risk Factors |
topic |
Cardiovascular Diseases/mortality Plaque, Atherosclerotic Coronary Artery Disease/diagnosis Calcium Signaling Coronary, Angiotomography Risk Factors |
description |
Abstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20180063 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.110 n.5 2018 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
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1752126568696643584 |