Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography

Detalhes bibliográficos
Autor(a) principal: Gabriel,Fabíola Santos
Data de Publicação: 2018
Outros Autores: Gonçalves,Luiz Flávio Galvão, Melo,Enaldo Vieira de, Sousa,Antônio Carlos Sobral, Pinto,Ibraim Masciarelli Francisco, Santana,Sara Melo Macedo, Matos,Carlos José Oliveira de, Souto,Maria Júlia Silveira, Conceição,Flávio Mateus do Sacramento, Oliveira,Joselina Luzia Menezes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Cardiologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420
Resumo: Abstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers.
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spelling Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography AngiographyCardiovascular Diseases/mortalityPlaque, AtheroscleroticCoronary Artery Disease/diagnosisCalcium SignalingCoronary, AngiotomographyRisk FactorsAbstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers.Sociedade Brasileira de Cardiologia - SBC2018-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420Arquivos Brasileiros de Cardiologia v.110 n.5 2018reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20180063info:eu-repo/semantics/openAccessGabriel,Fabíola SantosGonçalves,Luiz Flávio GalvãoMelo,Enaldo Vieira deSousa,Antônio Carlos SobralPinto,Ibraim Masciarelli FranciscoSantana,Sara Melo MacedoMatos,Carlos José Oliveira deSouto,Maria Júlia SilveiraConceição,Flávio Mateus do SacramentoOliveira,Joselina Luzia Menezeseng2018-05-30T00:00:00Zoai:scielo:S0066-782X2018000500420Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2018-05-30T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false
dc.title.none.fl_str_mv Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
title Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
spellingShingle Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
Gabriel,Fabíola Santos
Cardiovascular Diseases/mortality
Plaque, Atherosclerotic
Coronary Artery Disease/diagnosis
Calcium Signaling
Coronary, Angiotomography
Risk Factors
title_short Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
title_full Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
title_fullStr Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
title_full_unstemmed Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
title_sort Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography
author Gabriel,Fabíola Santos
author_facet Gabriel,Fabíola Santos
Gonçalves,Luiz Flávio Galvão
Melo,Enaldo Vieira de
Sousa,Antônio Carlos Sobral
Pinto,Ibraim Masciarelli Francisco
Santana,Sara Melo Macedo
Matos,Carlos José Oliveira de
Souto,Maria Júlia Silveira
Conceição,Flávio Mateus do Sacramento
Oliveira,Joselina Luzia Menezes
author_role author
author2 Gonçalves,Luiz Flávio Galvão
Melo,Enaldo Vieira de
Sousa,Antônio Carlos Sobral
Pinto,Ibraim Masciarelli Francisco
Santana,Sara Melo Macedo
Matos,Carlos José Oliveira de
Souto,Maria Júlia Silveira
Conceição,Flávio Mateus do Sacramento
Oliveira,Joselina Luzia Menezes
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gabriel,Fabíola Santos
Gonçalves,Luiz Flávio Galvão
Melo,Enaldo Vieira de
Sousa,Antônio Carlos Sobral
Pinto,Ibraim Masciarelli Francisco
Santana,Sara Melo Macedo
Matos,Carlos José Oliveira de
Souto,Maria Júlia Silveira
Conceição,Flávio Mateus do Sacramento
Oliveira,Joselina Luzia Menezes
dc.subject.por.fl_str_mv Cardiovascular Diseases/mortality
Plaque, Atherosclerotic
Coronary Artery Disease/diagnosis
Calcium Signaling
Coronary, Angiotomography
Risk Factors
topic Cardiovascular Diseases/mortality
Plaque, Atherosclerotic
Coronary Artery Disease/diagnosis
Calcium Signaling
Coronary, Angiotomography
Risk Factors
description Abstract Background: In view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature. Objective: To evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA). Methods: This is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted. Results: The frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable. Conclusions: The frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500420
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/abc.20180063
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
dc.source.none.fl_str_mv Arquivos Brasileiros de Cardiologia v.110 n.5 2018
reponame:Arquivos Brasileiros de Cardiologia (Online)
instname:Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
instname_str Sociedade Brasileira de Cardiologia (SBC)
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reponame_str Arquivos Brasileiros de Cardiologia (Online)
collection Arquivos Brasileiros de Cardiologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)
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