Vitamin D Deficiency and Cardiovascular Diseases
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Journal of Cardiovascular Sciences (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000400422 |
Resumo: | Abstract Vitamin D is considered a steroid hormone with a broad spectrum of action in the human body. Its action arises from the binding of its active metabolite (1α,25-dihydroxyvitamin D) to its receptor (VDR), which is present throughout the body, including vascular smooth muscle cells and cardiomyocytes. Initially, vitamin D deficiency was related only to changes in the musculoskeletal system, but in recent years, researchers have demonstrated its relationship with several pathologies related to other systems, such as cardiovascular diseases. The objective of this study is to review vitamin D’s pathophysiology, describe its relationship with cardiovascular diseases based on the most recent publications, and highlight the results of vitamin supplementation in the prevention of such pathologies. |
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International Journal of Cardiovascular Sciences (Online) |
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Vitamin D Deficiency and Cardiovascular DiseasesVitamin D Deficiency/physiopathologyCardiovascular DiseasesSolar RadiationCalciumPhosphorusAbstract Vitamin D is considered a steroid hormone with a broad spectrum of action in the human body. Its action arises from the binding of its active metabolite (1α,25-dihydroxyvitamin D) to its receptor (VDR), which is present throughout the body, including vascular smooth muscle cells and cardiomyocytes. Initially, vitamin D deficiency was related only to changes in the musculoskeletal system, but in recent years, researchers have demonstrated its relationship with several pathologies related to other systems, such as cardiovascular diseases. The objective of this study is to review vitamin D’s pathophysiology, describe its relationship with cardiovascular diseases based on the most recent publications, and highlight the results of vitamin supplementation in the prevention of such pathologies.Sociedade Brasileira de Cardiologia2018-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000400422International Journal of Cardiovascular Sciences v.31 n.4 2018reponame:International Journal of Cardiovascular Sciences (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/2359-4802.20180025info:eu-repo/semantics/openAccessJorge,Antonio José LagoeiroCordeiro,Jamerson ReisRosa,Maria Luiza GarciaBianchi,Diego Braga Camposeng2018-07-12T00:00:00Zoai:scielo:S2359-56472018000400422Revistahttp://publicacoes.cardiol.br/portal/ijcshttps://old.scielo.br/oai/scielo-oai.phptailanerodrigues@cardiol.br||revistaijcs@cardiol.br2359-56472359-4802opendoar:2018-07-12T00:00International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Vitamin D Deficiency and Cardiovascular Diseases |
title |
Vitamin D Deficiency and Cardiovascular Diseases |
spellingShingle |
Vitamin D Deficiency and Cardiovascular Diseases Jorge,Antonio José Lagoeiro Vitamin D Deficiency/physiopathology Cardiovascular Diseases Solar Radiation Calcium Phosphorus |
title_short |
Vitamin D Deficiency and Cardiovascular Diseases |
title_full |
Vitamin D Deficiency and Cardiovascular Diseases |
title_fullStr |
Vitamin D Deficiency and Cardiovascular Diseases |
title_full_unstemmed |
Vitamin D Deficiency and Cardiovascular Diseases |
title_sort |
Vitamin D Deficiency and Cardiovascular Diseases |
author |
Jorge,Antonio José Lagoeiro |
author_facet |
Jorge,Antonio José Lagoeiro Cordeiro,Jamerson Reis Rosa,Maria Luiza Garcia Bianchi,Diego Braga Campos |
author_role |
author |
author2 |
Cordeiro,Jamerson Reis Rosa,Maria Luiza Garcia Bianchi,Diego Braga Campos |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Jorge,Antonio José Lagoeiro Cordeiro,Jamerson Reis Rosa,Maria Luiza Garcia Bianchi,Diego Braga Campos |
dc.subject.por.fl_str_mv |
Vitamin D Deficiency/physiopathology Cardiovascular Diseases Solar Radiation Calcium Phosphorus |
topic |
Vitamin D Deficiency/physiopathology Cardiovascular Diseases Solar Radiation Calcium Phosphorus |
description |
Abstract Vitamin D is considered a steroid hormone with a broad spectrum of action in the human body. Its action arises from the binding of its active metabolite (1α,25-dihydroxyvitamin D) to its receptor (VDR), which is present throughout the body, including vascular smooth muscle cells and cardiomyocytes. Initially, vitamin D deficiency was related only to changes in the musculoskeletal system, but in recent years, researchers have demonstrated its relationship with several pathologies related to other systems, such as cardiovascular diseases. The objective of this study is to review vitamin D’s pathophysiology, describe its relationship with cardiovascular diseases based on the most recent publications, and highlight the results of vitamin supplementation in the prevention of such pathologies. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000400422 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000400422 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/2359-4802.20180025 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia |
dc.source.none.fl_str_mv |
International Journal of Cardiovascular Sciences v.31 n.4 2018 reponame:International Journal of Cardiovascular Sciences (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
International Journal of Cardiovascular Sciences (Online) |
collection |
International Journal of Cardiovascular Sciences (Online) |
repository.name.fl_str_mv |
International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
tailanerodrigues@cardiol.br||revistaijcs@cardiol.br |
_version_ |
1754732625277222912 |