Intestinal Microbiota and Cardiovascular Diseases
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Journal of Cardiovascular Sciences (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000500462 |
Resumo: | Abstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the absorption and metabolism of foods (protein, fat and carbohydrate). One example of the multiple actions of the gut microbiota is the bidirectional relationship between the intestine and the brain, the so-called “gut/brain axis”. Furthermore, metabolites produced by gut microbiota can induce effects locally or at distance, which suggests that the intestine is an endocrine organ. Given the participation of the gut microbiota in several diseases, there is great interest in strategies that may positively affect the gut flora and prevent or even treat diseases. Among these strategies, lifestyle change, but specially diet modulation has gained importance. In this article, we review the mechanisms through which intestinal microbiota participates in cardiovascular diseases and possible therapeutic interventions. |
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International Journal of Cardiovascular Sciences (Online) |
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Intestinal Microbiota and Cardiovascular DiseasesCardiovascular DiseasesGastrointestinal Microbiome/physiologyRisk FactorsHypertensionDiabetes MellitusObesityNeoplasmsAlzheimer DiseaseMetabolismAtherosclerosisDiet, MediterraneanAbstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the absorption and metabolism of foods (protein, fat and carbohydrate). One example of the multiple actions of the gut microbiota is the bidirectional relationship between the intestine and the brain, the so-called “gut/brain axis”. Furthermore, metabolites produced by gut microbiota can induce effects locally or at distance, which suggests that the intestine is an endocrine organ. Given the participation of the gut microbiota in several diseases, there is great interest in strategies that may positively affect the gut flora and prevent or even treat diseases. Among these strategies, lifestyle change, but specially diet modulation has gained importance. In this article, we review the mechanisms through which intestinal microbiota participates in cardiovascular diseases and possible therapeutic interventions.Sociedade Brasileira de Cardiologia2020-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000500462International Journal of Cardiovascular Sciences v.33 n.5 2020reponame:International Journal of Cardiovascular Sciences (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.36660/ijcs.20200043info:eu-repo/semantics/openAccessLuz,Protásio L. daHaas,Elisa AlbertonFavarato,Desiderioeng2020-11-23T00:00:00Zoai:scielo:S2359-56472020000500462Revistahttp://publicacoes.cardiol.br/portal/ijcshttps://old.scielo.br/oai/scielo-oai.phptailanerodrigues@cardiol.br||revistaijcs@cardiol.br2359-56472359-4802opendoar:2020-11-23T00:00International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Intestinal Microbiota and Cardiovascular Diseases |
title |
Intestinal Microbiota and Cardiovascular Diseases |
spellingShingle |
Intestinal Microbiota and Cardiovascular Diseases Luz,Protásio L. da Cardiovascular Diseases Gastrointestinal Microbiome/physiology Risk Factors Hypertension Diabetes Mellitus Obesity Neoplasms Alzheimer Disease Metabolism Atherosclerosis Diet, Mediterranean |
title_short |
Intestinal Microbiota and Cardiovascular Diseases |
title_full |
Intestinal Microbiota and Cardiovascular Diseases |
title_fullStr |
Intestinal Microbiota and Cardiovascular Diseases |
title_full_unstemmed |
Intestinal Microbiota and Cardiovascular Diseases |
title_sort |
Intestinal Microbiota and Cardiovascular Diseases |
author |
Luz,Protásio L. da |
author_facet |
Luz,Protásio L. da Haas,Elisa Alberton Favarato,Desiderio |
author_role |
author |
author2 |
Haas,Elisa Alberton Favarato,Desiderio |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Luz,Protásio L. da Haas,Elisa Alberton Favarato,Desiderio |
dc.subject.por.fl_str_mv |
Cardiovascular Diseases Gastrointestinal Microbiome/physiology Risk Factors Hypertension Diabetes Mellitus Obesity Neoplasms Alzheimer Disease Metabolism Atherosclerosis Diet, Mediterranean |
topic |
Cardiovascular Diseases Gastrointestinal Microbiome/physiology Risk Factors Hypertension Diabetes Mellitus Obesity Neoplasms Alzheimer Disease Metabolism Atherosclerosis Diet, Mediterranean |
description |
Abstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the absorption and metabolism of foods (protein, fat and carbohydrate). One example of the multiple actions of the gut microbiota is the bidirectional relationship between the intestine and the brain, the so-called “gut/brain axis”. Furthermore, metabolites produced by gut microbiota can induce effects locally or at distance, which suggests that the intestine is an endocrine organ. Given the participation of the gut microbiota in several diseases, there is great interest in strategies that may positively affect the gut flora and prevent or even treat diseases. Among these strategies, lifestyle change, but specially diet modulation has gained importance. In this article, we review the mechanisms through which intestinal microbiota participates in cardiovascular diseases and possible therapeutic interventions. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000500462 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000500462 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.36660/ijcs.20200043 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia |
dc.source.none.fl_str_mv |
International Journal of Cardiovascular Sciences v.33 n.5 2020 reponame:International Journal of Cardiovascular Sciences (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
International Journal of Cardiovascular Sciences (Online) |
collection |
International Journal of Cardiovascular Sciences (Online) |
repository.name.fl_str_mv |
International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
tailanerodrigues@cardiol.br||revistaijcs@cardiol.br |
_version_ |
1754732626560679936 |