Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Cardiovascular Surgery (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000100003 |
Resumo: | Abstract Objective: Transcatheter aortic valve replacement has been an alternative to invasive treatment for symptomatic severe aortic stenosis in high risk patients. The primary endpoint was 30-day and 1-year mortality from any cause. Secondary endpoints were to compare the clinical and echocardiographic variation pre-and post- transcatheter aortic valve replacement, and the occurrence of complications throughout a 4-year follow-up period. Methods: This prospective cohort, nestled to a multicenter study (Registro Brasileiro de Implante de Bioprótese por Cateter), describes the experience of a public tertiary center in transcatheter aortic valve replacement. All patients who underwent this procedure between October 2011 and February 2016 were included. Results: Fifty-eight patients underwent transcatheter aortic valve replacement. The 30-day all-cause mortality was 5.2% (n=3) and after 1 year was 17.2% (n=10). A significant improvement in New York Heart Association functional classification was observed when comparing pre-and post- transcatheter aortic valve replacement (III or IV 84.4% versus 5.8%; P<0.001). A decline in peak was observed (P<0.001) and mean (P<0.001) systolic transaortic gradient. The results of peak and mean post-implant transaortic gradient were sustained after one year (P=0.29 and P=0.36, respectively). Left ventricular ejection fraction did not change significantly during follow-up (P=0.41). The most frequent complications were bleeding (28.9%), the need for permanent pacemaker (27.6%) and acute renal injury (20.6%). Conclusion: Mortality and complications in this study were consistent with worldwide experience. Transcatheter aortic valve replacement had positive clinical and hemodynamic results, when comparing pre-and post-procedure, and the hemodynamic profile of the prosthesis was sustained throughout follow-up. |
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Brazilian Journal of Cardiovascular Surgery (Online) |
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Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care CenterTranscatheter Aortic Valve ReplacementHeart Valve Prosthesis ImplantationAortic Valve Stenosis/surgeryAbstract Objective: Transcatheter aortic valve replacement has been an alternative to invasive treatment for symptomatic severe aortic stenosis in high risk patients. The primary endpoint was 30-day and 1-year mortality from any cause. Secondary endpoints were to compare the clinical and echocardiographic variation pre-and post- transcatheter aortic valve replacement, and the occurrence of complications throughout a 4-year follow-up period. Methods: This prospective cohort, nestled to a multicenter study (Registro Brasileiro de Implante de Bioprótese por Cateter), describes the experience of a public tertiary center in transcatheter aortic valve replacement. All patients who underwent this procedure between October 2011 and February 2016 were included. Results: Fifty-eight patients underwent transcatheter aortic valve replacement. The 30-day all-cause mortality was 5.2% (n=3) and after 1 year was 17.2% (n=10). A significant improvement in New York Heart Association functional classification was observed when comparing pre-and post- transcatheter aortic valve replacement (III or IV 84.4% versus 5.8%; P<0.001). A decline in peak was observed (P<0.001) and mean (P<0.001) systolic transaortic gradient. The results of peak and mean post-implant transaortic gradient were sustained after one year (P=0.29 and P=0.36, respectively). Left ventricular ejection fraction did not change significantly during follow-up (P=0.41). The most frequent complications were bleeding (28.9%), the need for permanent pacemaker (27.6%) and acute renal injury (20.6%). Conclusion: Mortality and complications in this study were consistent with worldwide experience. Transcatheter aortic valve replacement had positive clinical and hemodynamic results, when comparing pre-and post-procedure, and the hemodynamic profile of the prosthesis was sustained throughout follow-up.Sociedade Brasileira de Cirurgia Cardiovascular2018-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000100003Brazilian Journal of Cardiovascular Surgery v.33 n.1 2018reponame:Brazilian Journal of Cardiovascular Surgery (Online)instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)instacron:SBCCV10.21470/1678-9741-2017-0117info:eu-repo/semantics/openAccessAzevedo,Fabiula SchwartzCorrea,Marcelo GoulartPaula,Débora Holanda GonçalvesFelix,Alex dos SantosBelém,Luciano Herman JuaçabaMendes,Ana Paula ChedidSilva,Valeria GonçalvesMarques,Bruno MirandaMonteiro,Andrey José de OliveiraWeksler,ClaraColafranceschi,Alexandre SicilianoKasal,Daniel Arthur Barataeng2018-03-27T00:00:00Zoai:scielo:S0102-76382018000100003Revistahttp://www.rbccv.org.br/https://old.scielo.br/oai/scielo-oai.php||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br1678-97410102-7638opendoar:2018-03-27T00:00Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)false |
dc.title.none.fl_str_mv |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
title |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
spellingShingle |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center Azevedo,Fabiula Schwartz Transcatheter Aortic Valve Replacement Heart Valve Prosthesis Implantation Aortic Valve Stenosis/surgery |
title_short |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
title_full |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
title_fullStr |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
title_full_unstemmed |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
title_sort |
Transcatheter Aortic Valve Replacement: The Experience of One Brazilian Health Care Center |
author |
Azevedo,Fabiula Schwartz |
author_facet |
Azevedo,Fabiula Schwartz Correa,Marcelo Goulart Paula,Débora Holanda Gonçalves Felix,Alex dos Santos Belém,Luciano Herman Juaçaba Mendes,Ana Paula Chedid Silva,Valeria Gonçalves Marques,Bruno Miranda Monteiro,Andrey José de Oliveira Weksler,Clara Colafranceschi,Alexandre Siciliano Kasal,Daniel Arthur Barata |
author_role |
author |
author2 |
Correa,Marcelo Goulart Paula,Débora Holanda Gonçalves Felix,Alex dos Santos Belém,Luciano Herman Juaçaba Mendes,Ana Paula Chedid Silva,Valeria Gonçalves Marques,Bruno Miranda Monteiro,Andrey José de Oliveira Weksler,Clara Colafranceschi,Alexandre Siciliano Kasal,Daniel Arthur Barata |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Azevedo,Fabiula Schwartz Correa,Marcelo Goulart Paula,Débora Holanda Gonçalves Felix,Alex dos Santos Belém,Luciano Herman Juaçaba Mendes,Ana Paula Chedid Silva,Valeria Gonçalves Marques,Bruno Miranda Monteiro,Andrey José de Oliveira Weksler,Clara Colafranceschi,Alexandre Siciliano Kasal,Daniel Arthur Barata |
dc.subject.por.fl_str_mv |
Transcatheter Aortic Valve Replacement Heart Valve Prosthesis Implantation Aortic Valve Stenosis/surgery |
topic |
Transcatheter Aortic Valve Replacement Heart Valve Prosthesis Implantation Aortic Valve Stenosis/surgery |
description |
Abstract Objective: Transcatheter aortic valve replacement has been an alternative to invasive treatment for symptomatic severe aortic stenosis in high risk patients. The primary endpoint was 30-day and 1-year mortality from any cause. Secondary endpoints were to compare the clinical and echocardiographic variation pre-and post- transcatheter aortic valve replacement, and the occurrence of complications throughout a 4-year follow-up period. Methods: This prospective cohort, nestled to a multicenter study (Registro Brasileiro de Implante de Bioprótese por Cateter), describes the experience of a public tertiary center in transcatheter aortic valve replacement. All patients who underwent this procedure between October 2011 and February 2016 were included. Results: Fifty-eight patients underwent transcatheter aortic valve replacement. The 30-day all-cause mortality was 5.2% (n=3) and after 1 year was 17.2% (n=10). A significant improvement in New York Heart Association functional classification was observed when comparing pre-and post- transcatheter aortic valve replacement (III or IV 84.4% versus 5.8%; P<0.001). A decline in peak was observed (P<0.001) and mean (P<0.001) systolic transaortic gradient. The results of peak and mean post-implant transaortic gradient were sustained after one year (P=0.29 and P=0.36, respectively). Left ventricular ejection fraction did not change significantly during follow-up (P=0.41). The most frequent complications were bleeding (28.9%), the need for permanent pacemaker (27.6%) and acute renal injury (20.6%). Conclusion: Mortality and complications in this study were consistent with worldwide experience. Transcatheter aortic valve replacement had positive clinical and hemodynamic results, when comparing pre-and post-procedure, and the hemodynamic profile of the prosthesis was sustained throughout follow-up. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000100003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382018000100003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21470/1678-9741-2017-0117 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
dc.source.none.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery v.33 n.1 2018 reponame:Brazilian Journal of Cardiovascular Surgery (Online) instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV |
instname_str |
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
instacron_str |
SBCCV |
institution |
SBCCV |
reponame_str |
Brazilian Journal of Cardiovascular Surgery (Online) |
collection |
Brazilian Journal of Cardiovascular Surgery (Online) |
repository.name.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
repository.mail.fl_str_mv |
||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br |
_version_ |
1752126599878148096 |