Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats

Detalhes bibliográficos
Autor(a) principal: Lima,Ana Laura Sanches
Data de Publicação: 2020
Outros Autores: Gianini,Beatriz Schorro, Santana,Bruna Miranda, Santos,Carlos Henrique Marques dos, Dourado,Doroty Mesquita, Falcão,Juliano Seger, Bannwart,Lucas, Câmara,Sara Jéssica Falcão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100056
Resumo: Abstract Rationale Fistulotomy is a procedure widely used in the treatment of anal fistulas but is associated with varying degrees of fecal incontinence that could be minimized by previous use of sedentum, and the material used may influence the outcome. Purpouse To compare cotton and silastic used as setons in the spacing of the sphincter cables of rats subjected to fistulotomy. Method Thirty Wistar rats were used, which after 30 days of fistula production were distributed in: Control Group (GC): the steel wire was removed, followed by fistulotomy; Cotton Group (GA) and Silastic Group (GS), in which were applied cotton and silastic setons respectively for 30 days when fistulotomy was performed; after seven days, euthanasia and removal of the specimens were performed for histological study, and the results were submitted to statistical assessment using Kruskal–Wallis non-parametric test, establishing a significance level of p < 0.05. Results The distance between the muscular cables was 107.9 µm in the GC, 82.4 µm in the GA and 53.5 µm in the GS (p = 0.00001). The mean inflammation scores were 1.9 in the CG, 1.0 in the GA and 0 in the GS (p < 0.05). The fibrosis scores were 1.1 in GC, 0.9 in GA and 0.6 in GS (p > 0.05). Conclusion The silastic seton prior to fistulotomy caused less detachment of the muscular cables and less local inflammatory process.
id SBCP-1_01027b2e176c0ccfca6db281d164c544
oai_identifier_str oai:scielo:S2237-93632020000100056
network_acronym_str SBCP-1
network_name_str Journal of Coloproctology (Rio de Janeiro. Online)
repository_id_str
spelling Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in ratsRectal fistulaCottonSilasticFistulotomyFecal incontinenceAbstract Rationale Fistulotomy is a procedure widely used in the treatment of anal fistulas but is associated with varying degrees of fecal incontinence that could be minimized by previous use of sedentum, and the material used may influence the outcome. Purpouse To compare cotton and silastic used as setons in the spacing of the sphincter cables of rats subjected to fistulotomy. Method Thirty Wistar rats were used, which after 30 days of fistula production were distributed in: Control Group (GC): the steel wire was removed, followed by fistulotomy; Cotton Group (GA) and Silastic Group (GS), in which were applied cotton and silastic setons respectively for 30 days when fistulotomy was performed; after seven days, euthanasia and removal of the specimens were performed for histological study, and the results were submitted to statistical assessment using Kruskal–Wallis non-parametric test, establishing a significance level of p < 0.05. Results The distance between the muscular cables was 107.9 µm in the GC, 82.4 µm in the GA and 53.5 µm in the GS (p = 0.00001). The mean inflammation scores were 1.9 in the CG, 1.0 in the GA and 0 in the GS (p < 0.05). The fibrosis scores were 1.1 in GC, 0.9 in GA and 0.6 in GS (p > 0.05). Conclusion The silastic seton prior to fistulotomy caused less detachment of the muscular cables and less local inflammatory process.Sociedade Brasileira de Coloproctologia2020-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100056Journal of Coloproctology (Rio de Janeiro) v.40 n.1 2020reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2019.09.002info:eu-repo/semantics/openAccessLima,Ana Laura SanchesGianini,Beatriz SchorroSantana,Bruna MirandaSantos,Carlos Henrique Marques dosDourado,Doroty MesquitaFalcão,Juliano SegerBannwart,LucasCâmara,Sara Jéssica Falcãoeng2020-03-19T00:00:00Zoai:scielo:S2237-93632020000100056Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2020-03-19T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
title Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
spellingShingle Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
Lima,Ana Laura Sanches
Rectal fistula
Cotton
Silastic
Fistulotomy
Fecal incontinence
title_short Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
title_full Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
title_fullStr Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
title_full_unstemmed Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
title_sort Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats
author Lima,Ana Laura Sanches
author_facet Lima,Ana Laura Sanches
Gianini,Beatriz Schorro
Santana,Bruna Miranda
Santos,Carlos Henrique Marques dos
Dourado,Doroty Mesquita
Falcão,Juliano Seger
Bannwart,Lucas
Câmara,Sara Jéssica Falcão
author_role author
author2 Gianini,Beatriz Schorro
Santana,Bruna Miranda
Santos,Carlos Henrique Marques dos
Dourado,Doroty Mesquita
Falcão,Juliano Seger
Bannwart,Lucas
Câmara,Sara Jéssica Falcão
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lima,Ana Laura Sanches
Gianini,Beatriz Schorro
Santana,Bruna Miranda
Santos,Carlos Henrique Marques dos
Dourado,Doroty Mesquita
Falcão,Juliano Seger
Bannwart,Lucas
Câmara,Sara Jéssica Falcão
dc.subject.por.fl_str_mv Rectal fistula
Cotton
Silastic
Fistulotomy
Fecal incontinence
topic Rectal fistula
Cotton
Silastic
Fistulotomy
Fecal incontinence
description Abstract Rationale Fistulotomy is a procedure widely used in the treatment of anal fistulas but is associated with varying degrees of fecal incontinence that could be minimized by previous use of sedentum, and the material used may influence the outcome. Purpouse To compare cotton and silastic used as setons in the spacing of the sphincter cables of rats subjected to fistulotomy. Method Thirty Wistar rats were used, which after 30 days of fistula production were distributed in: Control Group (GC): the steel wire was removed, followed by fistulotomy; Cotton Group (GA) and Silastic Group (GS), in which were applied cotton and silastic setons respectively for 30 days when fistulotomy was performed; after seven days, euthanasia and removal of the specimens were performed for histological study, and the results were submitted to statistical assessment using Kruskal–Wallis non-parametric test, establishing a significance level of p < 0.05. Results The distance between the muscular cables was 107.9 µm in the GC, 82.4 µm in the GA and 53.5 µm in the GS (p = 0.00001). The mean inflammation scores were 1.9 in the CG, 1.0 in the GA and 0 in the GS (p < 0.05). The fibrosis scores were 1.1 in GC, 0.9 in GA and 0.6 in GS (p > 0.05). Conclusion The silastic seton prior to fistulotomy caused less detachment of the muscular cables and less local inflammatory process.
publishDate 2020
dc.date.none.fl_str_mv 2020-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100056
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100056
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2019.09.002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.40 n.1 2020
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
institution SBCP
reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
_version_ 1752126478745600000