Clinical outcomes of Fournier's gangrene from a tertiary hospital

Detalhes bibliográficos
Autor(a) principal: Corrêa Neto,Isaac José Felippe
Data de Publicação: 2012
Outros Autores: Sia,Otávio Nunes, Rolim,Alexander Sá, Souza,Rogério Freitas Lino, Watté,Hugo Henriques, Robles,Laércio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000400008
Resumo: Fournier's gangrene is a progressive polymicrobial necrotizing fasciitis, caused by aerobic and anaerobic organisms. It causes an endarteritis obliterans leading to vessel thrombosis and subsequent cutaneous and subcutaneous necrosis of the perineal region. OBJECTIVE: It was to describe the clinical outcomes of Fournier's gangrene treated at the Hospital Santa Marcelina, São Paulo (SP), Brazil. METHODS: This was a retrospective study conducted at the Hospital Santa Marcelina, in São Paulo (SP), Brazil, with patients with necrotizing fasciitis from September 2008 to March 2011. RESULTS: We included 13 patients, most were males, and the mean age was 51.8 years old. Five of them presented with systemic inflammatory response syndrome, only two had no comorbidities and 23% were obese. The most prevalent etiologic agent was E. coli, and the most common antibiotic regimen consisted of a combination of metronidazole with ciprofloxacin. The average number of surgical procedures performed by patient was 2.07, and 7 patients (53.8%) underwent colostomy formation. The mortality rate was 30.8%. CONCLUSIONS: Fournier's gangrene is a severe disease, with high mortality rates. The physician should suspect its diagnosis early and have an aggressive treatment approach to achieve better outcomes.
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spelling Clinical outcomes of Fournier's gangrene from a tertiary hospitalFournier gangreneperineumcolostomybacterial infectionsnecrosisFournier's gangrene is a progressive polymicrobial necrotizing fasciitis, caused by aerobic and anaerobic organisms. It causes an endarteritis obliterans leading to vessel thrombosis and subsequent cutaneous and subcutaneous necrosis of the perineal region. OBJECTIVE: It was to describe the clinical outcomes of Fournier's gangrene treated at the Hospital Santa Marcelina, São Paulo (SP), Brazil. METHODS: This was a retrospective study conducted at the Hospital Santa Marcelina, in São Paulo (SP), Brazil, with patients with necrotizing fasciitis from September 2008 to March 2011. RESULTS: We included 13 patients, most were males, and the mean age was 51.8 years old. Five of them presented with systemic inflammatory response syndrome, only two had no comorbidities and 23% were obese. The most prevalent etiologic agent was E. coli, and the most common antibiotic regimen consisted of a combination of metronidazole with ciprofloxacin. The average number of surgical procedures performed by patient was 2.07, and 7 patients (53.8%) underwent colostomy formation. The mortality rate was 30.8%. CONCLUSIONS: Fournier's gangrene is a severe disease, with high mortality rates. The physician should suspect its diagnosis early and have an aggressive treatment approach to achieve better outcomes.Sociedade Brasileira de Coloproctologia2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000400008Journal of Coloproctology (Rio de Janeiro) v.32 n.4 2012reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1590/S2237-93632012000400008info:eu-repo/semantics/openAccessCorrêa Neto,Isaac José FelippeSia,Otávio NunesRolim,Alexander SáSouza,Rogério Freitas LinoWatté,Hugo HenriquesRobles,Laércioeng2013-07-02T00:00:00Zoai:scielo:S2237-93632012000400008Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2013-07-02T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv Clinical outcomes of Fournier's gangrene from a tertiary hospital
title Clinical outcomes of Fournier's gangrene from a tertiary hospital
spellingShingle Clinical outcomes of Fournier's gangrene from a tertiary hospital
Corrêa Neto,Isaac José Felippe
Fournier gangrene
perineum
colostomy
bacterial infections
necrosis
title_short Clinical outcomes of Fournier's gangrene from a tertiary hospital
title_full Clinical outcomes of Fournier's gangrene from a tertiary hospital
title_fullStr Clinical outcomes of Fournier's gangrene from a tertiary hospital
title_full_unstemmed Clinical outcomes of Fournier's gangrene from a tertiary hospital
title_sort Clinical outcomes of Fournier's gangrene from a tertiary hospital
author Corrêa Neto,Isaac José Felippe
author_facet Corrêa Neto,Isaac José Felippe
Sia,Otávio Nunes
Rolim,Alexander Sá
Souza,Rogério Freitas Lino
Watté,Hugo Henriques
Robles,Laércio
author_role author
author2 Sia,Otávio Nunes
Rolim,Alexander Sá
Souza,Rogério Freitas Lino
Watté,Hugo Henriques
Robles,Laércio
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Corrêa Neto,Isaac José Felippe
Sia,Otávio Nunes
Rolim,Alexander Sá
Souza,Rogério Freitas Lino
Watté,Hugo Henriques
Robles,Laércio
dc.subject.por.fl_str_mv Fournier gangrene
perineum
colostomy
bacterial infections
necrosis
topic Fournier gangrene
perineum
colostomy
bacterial infections
necrosis
description Fournier's gangrene is a progressive polymicrobial necrotizing fasciitis, caused by aerobic and anaerobic organisms. It causes an endarteritis obliterans leading to vessel thrombosis and subsequent cutaneous and subcutaneous necrosis of the perineal region. OBJECTIVE: It was to describe the clinical outcomes of Fournier's gangrene treated at the Hospital Santa Marcelina, São Paulo (SP), Brazil. METHODS: This was a retrospective study conducted at the Hospital Santa Marcelina, in São Paulo (SP), Brazil, with patients with necrotizing fasciitis from September 2008 to March 2011. RESULTS: We included 13 patients, most were males, and the mean age was 51.8 years old. Five of them presented with systemic inflammatory response syndrome, only two had no comorbidities and 23% were obese. The most prevalent etiologic agent was E. coli, and the most common antibiotic regimen consisted of a combination of metronidazole with ciprofloxacin. The average number of surgical procedures performed by patient was 2.07, and 7 patients (53.8%) underwent colostomy formation. The mortality rate was 30.8%. CONCLUSIONS: Fournier's gangrene is a severe disease, with high mortality rates. The physician should suspect its diagnosis early and have an aggressive treatment approach to achieve better outcomes.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000400008
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S2237-93632012000400008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.32 n.4 2012
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
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reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
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