Buschke-Loewenstein Tumor: a case series from Brazil
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of Coloproctology (Rio de Janeiro. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632014000400202 |
Resumo: | ABSTRACTBuschke-Loewenstein Tumor or giant condyloma acuminatum is a disease caused by a DNA virus, the self-inoculable human papilloma virus (HPV), being sexually transmitted. Histologically BLT is a benign tumor, but with malignant clinical behavior and a high propensity for local recurrence and malignant degeneration. The clinical picture consists of the presence of a cauliflower-like bulky condylomatous perianal mass with multiple fistulous tracts, which can cause great destruction of the anal canal, with invasion of adjacent tissues. Bleeding, foul odor, local pain and weight loss are also described. The diagnosis is established by biopsy, that should exclude the presence of malignant transformation, which occurs in 30-50% of cases. Associated with a biopsy, the hybridization test may be performed to diagnose HPV infection, especially subtypes 6 and 11, that are commonly related. The treatment of choice is radical surgical excision; however, those patients presenting with extensive fistulous lesions may require a temporary colostomy. Some authors advocate an abdominoperineal resection in cases of infiltration of the sphincter or rectum. This study was designed to evaluate the experience of the service of Coloproctology at a referral hospital in Northeastern Brazil with this rare entity, contributing to world literature in addressing this disease. |
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Buschke-Loewenstein Tumor: a case series from BrazilGiant condyloma acuminatumBuschke-Loewenstein TumorVerrucous carcinomaHuman papillomavirusABSTRACTBuschke-Loewenstein Tumor or giant condyloma acuminatum is a disease caused by a DNA virus, the self-inoculable human papilloma virus (HPV), being sexually transmitted. Histologically BLT is a benign tumor, but with malignant clinical behavior and a high propensity for local recurrence and malignant degeneration. The clinical picture consists of the presence of a cauliflower-like bulky condylomatous perianal mass with multiple fistulous tracts, which can cause great destruction of the anal canal, with invasion of adjacent tissues. Bleeding, foul odor, local pain and weight loss are also described. The diagnosis is established by biopsy, that should exclude the presence of malignant transformation, which occurs in 30-50% of cases. Associated with a biopsy, the hybridization test may be performed to diagnose HPV infection, especially subtypes 6 and 11, that are commonly related. The treatment of choice is radical surgical excision; however, those patients presenting with extensive fistulous lesions may require a temporary colostomy. Some authors advocate an abdominoperineal resection in cases of infiltration of the sphincter or rectum. This study was designed to evaluate the experience of the service of Coloproctology at a referral hospital in Northeastern Brazil with this rare entity, contributing to world literature in addressing this disease.Sociedade Brasileira de Coloproctologia2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632014000400202Journal of Coloproctology (Rio de Janeiro) v.34 n.4 2014reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2014.08.011info:eu-repo/semantics/openAccessLucena,Maurilio Toscano deGóis,Luciana HoraApel,AlineFilho,José FigueiroaSilva,Maurício José de Matos eJusto,Cláudia Rosali EsmeraldoCarvalho,Joaquim Herbênio CostaMonteiro,Fernandoeng2015-09-04T00:00:00Zoai:scielo:S2237-93632014000400202Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2015-09-04T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false |
dc.title.none.fl_str_mv |
Buschke-Loewenstein Tumor: a case series from Brazil |
title |
Buschke-Loewenstein Tumor: a case series from Brazil |
spellingShingle |
Buschke-Loewenstein Tumor: a case series from Brazil Lucena,Maurilio Toscano de Giant condyloma acuminatum Buschke-Loewenstein Tumor Verrucous carcinoma Human papillomavirus |
title_short |
Buschke-Loewenstein Tumor: a case series from Brazil |
title_full |
Buschke-Loewenstein Tumor: a case series from Brazil |
title_fullStr |
Buschke-Loewenstein Tumor: a case series from Brazil |
title_full_unstemmed |
Buschke-Loewenstein Tumor: a case series from Brazil |
title_sort |
Buschke-Loewenstein Tumor: a case series from Brazil |
author |
Lucena,Maurilio Toscano de |
author_facet |
Lucena,Maurilio Toscano de Góis,Luciana Hora Apel,Aline Filho,José Figueiroa Silva,Maurício José de Matos e Justo,Cláudia Rosali Esmeraldo Carvalho,Joaquim Herbênio Costa Monteiro,Fernando |
author_role |
author |
author2 |
Góis,Luciana Hora Apel,Aline Filho,José Figueiroa Silva,Maurício José de Matos e Justo,Cláudia Rosali Esmeraldo Carvalho,Joaquim Herbênio Costa Monteiro,Fernando |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Lucena,Maurilio Toscano de Góis,Luciana Hora Apel,Aline Filho,José Figueiroa Silva,Maurício José de Matos e Justo,Cláudia Rosali Esmeraldo Carvalho,Joaquim Herbênio Costa Monteiro,Fernando |
dc.subject.por.fl_str_mv |
Giant condyloma acuminatum Buschke-Loewenstein Tumor Verrucous carcinoma Human papillomavirus |
topic |
Giant condyloma acuminatum Buschke-Loewenstein Tumor Verrucous carcinoma Human papillomavirus |
description |
ABSTRACTBuschke-Loewenstein Tumor or giant condyloma acuminatum is a disease caused by a DNA virus, the self-inoculable human papilloma virus (HPV), being sexually transmitted. Histologically BLT is a benign tumor, but with malignant clinical behavior and a high propensity for local recurrence and malignant degeneration. The clinical picture consists of the presence of a cauliflower-like bulky condylomatous perianal mass with multiple fistulous tracts, which can cause great destruction of the anal canal, with invasion of adjacent tissues. Bleeding, foul odor, local pain and weight loss are also described. The diagnosis is established by biopsy, that should exclude the presence of malignant transformation, which occurs in 30-50% of cases. Associated with a biopsy, the hybridization test may be performed to diagnose HPV infection, especially subtypes 6 and 11, that are commonly related. The treatment of choice is radical surgical excision; however, those patients presenting with extensive fistulous lesions may require a temporary colostomy. Some authors advocate an abdominoperineal resection in cases of infiltration of the sphincter or rectum. This study was designed to evaluate the experience of the service of Coloproctology at a referral hospital in Northeastern Brazil with this rare entity, contributing to world literature in addressing this disease. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632014000400202 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632014000400202 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jcol.2014.08.011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Coloproctologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Coloproctologia |
dc.source.none.fl_str_mv |
Journal of Coloproctology (Rio de Janeiro) v.34 n.4 2014 reponame:Journal of Coloproctology (Rio de Janeiro. Online) instname:Sociedade Brasileira de Coloproctologia (SBCP) instacron:SBCP |
instname_str |
Sociedade Brasileira de Coloproctologia (SBCP) |
instacron_str |
SBCP |
institution |
SBCP |
reponame_str |
Journal of Coloproctology (Rio de Janeiro. Online) |
collection |
Journal of Coloproctology (Rio de Janeiro. Online) |
repository.name.fl_str_mv |
Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP) |
repository.mail.fl_str_mv |
||sbcp@sbcp.org.br |
_version_ |
1752126477479968768 |